Biotin is a water soluble vitamin necessary for growth, development, and energy production and may support healthy hair, skin, and nails. Biotin also acts as a cofactor for 5 carboxylases and plays an important role in balancing immune responses. Biotin is synthesized from tryptophan by intestinal bacteria and can also be found in foods such as meat, beans, milk, and cereal grains. Interestingly, when the human body is deficient in biotin, intestinal cells can actually increase the biotin uptake process, allowing the human host to feed off of biotin produced by the gut microbiome. Bacteroides fragilis, Prevotella copri, and several members of the Proteobacteria phylum possess a vitamin B7 biosynthesis pathway. In contrast, species belonging to Prevotella, Bifidobacterium, Clostridium, Ruminococcus, Faecalibacterium, and Lactobacillus are unable to produce biotin yet need it for survival, suggesting that these bacteria may compete with the host for biotin utilization.
Free biotin in the gut can change the composition of the gut microbiome and is linked to the overgrowth of Lactobacillus murinus and unfavorable outcomes. Furthermore, Bifidobacterium longum produces a B7 precursor that enhances vitamin B7 production by other intestinal bacteria. Gut bacteria only contribute about 5% of the daily recommended intake of B7 for adults, so it is important to ensure adequate biotin intake from the diet and/or supplementation.
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Elevated levels of Vitamin B7 (Biotin) on a BiomeFx test generally do not signify a health concern. Here are the key points:
While elevated biotin levels are generally not a cause for concern, it's important to note that extremely high levels could potentially affect the gut microbiome composition. As with any test result, it's advisable to consult with a healthcare professional for personalized interpretation and advice, especially if there are concerns about excessive supplementation or potential impacts on gut health.
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When biotin levels appear low on a BiomeFX panel, it indicates a potential deficiency. This could impact various bodily functions and the balance of the gut microbiome. If you notice low biotin levels, consider discussing dietary changes or supplementation with a healthcare professional.
Biotin, also known as vitamin B7, is a water-soluble vitamin essential for growth, development, and energy production. It supports healthy hair, skin, and nails, and plays a vital role in balancing immune responses. Importantly, biotin acts as a cofactor for five carboxylases - enzymes crucial for various metabolic processes in the body.
Biotin is found in foods such as meat, beans, milk, and cereal grains. Interestingly, it can also be synthesized from tryptophan by certain intestinal bacteria. When the human body is deficient in biotin, intestinal cells can increase their biotin uptake, allowing the host to utilize biotin produced by the gut microbiome.
The relationship between biotin and gut bacteria is complex:
While gut bacteria contribute to biotin production, they only provide about 5% of the daily recommended intake for adults. Therefore, ensuring adequate biotin intake from diet and/or supplementation is crucial for maintaining overall health and a balanced gut microbiome.
Biotin plays a significant role in both overall health and gut microbiome balance. While some gut bacteria can produce biotin, dietary sources remain crucial. Understanding the interplay between biotin, gut bacteria, and host health can help in maintaining optimal wellness and a balanced microbiome.
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Acetate production, Akkermansia muciniphila, Alpha Diversity, Ammonia production, Beta Diversity, Bifidobacterium adolescentis, Bifidobacterium longum, Bifidobacterium pseudocatenulatum, Bilophila wadsworthia, Butyrate production, Clostridium scindens, Escherichia coli, Estrogen recycling (Estrobolome), Eubacterium rectale, Faecalibacterium prausnitzii, Firmicutes:Bacteroidetes Ratio, GABA production, Glutathione production, Gut Microbiome Index (GMI), Histamine production, Hydrogen Sulfide (H2S) production, Indole production, Lactate production, Limosilactobacillus reuteri, Methane Production, Oxalobacter formigenes, P-Cresol (Phenol), Parabacteroides goldsteinii, Parabacteroides merdae, Pathogen Control Index, Phocaeicola vulgatus, Polyamine production, Prevotella:Bacteroides Ratio, Propionate production, Proteobacteria:Actinobacteria Ratio, Resistome Occurrence Index, Roseburia intestinalis, Ruminococcus bromii, Sutterella wadsworthensis, Vit B1 Thiamin, Vit B12 Cobalamin, Vit B2 Riboflavin, Vit B5 Pantothenic acid, Vit B6 Pyridoxine, Vit B7 Biotin, Vit B9 Folate, Vit K2 Menaquinone
