Parabacteroides merdae is a prominent bacterium in the human gut microbiota, often assessed in gut health panels due to its significant role in maintaining digestive health and contributing to the gut’s metabolic activities. This anaerobic bacterium is known for its involvement in the fermentation of dietary fibers, leading to the production of beneficial short-chain fatty acids (SCFAs) such as acetate and propionate, which are crucial for colon health. Parabacteroides merdae also plays a part in modulating the immune system and protecting against pathogenic bacteria. Its presence in balanced levels is often considered a marker of a healthy and diverse microbiota. Alterations in its abundance can be associated with various gastrointestinal conditions, including inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), and metabolic disorders. Monitoring Parabacteroides merdae on a gut test panel provides valuable insights into an individual’s gut health and can guide dietary and therapeutic interventions to restore and maintain a balanced gut ecosystem.
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Increased Levels of Parabacteroides merdae on a BiomeFx Panel:
Significance:
Conditions Associated with Increased Levels:
Possible Reasons for Increased Levels:
Potential Treatment Considerations:
Dietary Adjustments:
Lifestyle Modifications:
Medical Interventions:
Other Biomarkers That Are Correlated:
Nutrient Associations:
Specific Considerations:
Males vs. Females:
Young vs. Old:
Summary
Increased levels of Parabacteroides merdae indicate a potential imbalance in the gut microbiome, associated with several health conditions and influenced by diet, lifestyle, and medications. Addressing this imbalance typically involves dietary changes, lifestyle modifications, and sometimes medical interventions, with specific considerations based on age and gender.
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Low Levels of Parabacteroides merdae
What Low Levels Could Signify:
Gut Microbiota Imbalance: Low levels of Parabacteroides merdae may indicate an overall imbalance in the gut microbiota, known as dysbiosis. This imbalance can disrupt normal gut functions and lead to various health issues.
Reduced SCFA Production: Parabacteroides merdae is involved in the fermentation of dietary fibers, producing beneficial short-chain fatty acids (SCFAs) such as acetate and propionate. Low levels of this bacterium could result in decreased SCFA production, which is crucial for colon health, energy metabolism, and maintaining a healthy gut lining.
Weakened Immune Modulation: This bacterium plays a role in modulating the immune system. Low levels might be associated with impaired immune function in the gut, potentially making the gut more susceptible to infections and inflammatory conditions.
Increased Susceptibility to Pathogens: Parabacteroides merdae helps protect against pathogenic bacteria. Reduced levels may lead to a higher risk of colonization and overgrowth of harmful bacteria, contributing to gastrointestinal disorders.
Gastrointestinal Conditions: Alterations in the abundance of Parabacteroides merdae, including low levels, have been associated with various gastrointestinal conditions such as inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), and other metabolic disorders.
What To Do About It:
To address low levels of Parabacteroides merdae, consider the following steps:
Dietary Adjustments:
Probiotics and Prebiotics:
Monitor and Manage Gut Health:
Consult Healthcare Professionals:
Lifestyle Modifications:
Addressing low levels of Parabacteroides merdae involves a comprehensive approach to diet, gut health, and overall lifestyle. Working with healthcare professionals can provide tailored advice and support for restoring and maintaining a balanced gut ecosystem.
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Acetate production, Akkermansia muciniphila, Alpha Diversity, Ammonia production, Beta Diversity, Bifidobacterium adolescentis, Bifidobacterium longum, Bifidobacterium pseudocatenulatum, Bilophila wadsworthia, Butyrate production, Clostridium scindens, Escherichia coli, Estrogen recycling (Estrobolome), Eubacterium rectale, Faecalibacterium prausnitzii, Firmicutes:Bacteroidetes Ratio, GABA production, Glutathione production, Gut Microbiome Index (GMI), Histamine production, Hydrogen Sulfide (H2S) production, Indole production, Lactate production, Limosilactobacillus reuteri, Methane Production, Oxalobacter formigenes, P-Cresol (Phenol), Parabacteroides goldsteinii, Parabacteroides merdae, Pathogen Control Index, Phocaeicola vulgatus, Polyamine production, Prevotella:Bacteroides Ratio, Propionate production, Proteobacteria:Actinobacteria Ratio, Resistome Occurrence Index, Roseburia intestinalis, Ruminococcus bromii, Sutterella wadsworthensis, Vit B1 Thiamin, Vit B12 Cobalamin, Vit B2 Riboflavin, Vit B5 Pantothenic acid, Vit B6 Pyridoxine, Vit B7 Biotin, Vit B9 Folate, Vit K2 Menaquinone
