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Tau/Tau-P Ratio

Cerebrospinal fluid

Cerebrospinal Fluid (CSF) Analysis

Optimal range:   0.5 - 3 Ratio

Tau/Tau-P Ratio is a cerebrospinal fluid (CSF) biomarker used to evaluate the relationship between total tau and phosphorylated tau (pTau), providing critical insights into the underlying pathology of neurodegenerative diseases, particularly Alzheimer’s disease. This ratio reflects both the extent of neuronal damage (indicated by total tau) and the degree of tau protein hyperphosphorylation (indicated by pTau).

The Tau/Tau-P ratio enhances the diagnostic specificity of Alzheimer’s disease when interpreted alongside amyloid-beta (Aβ42) levels and other CSF biomarkers. It helps differentiate Alzheimer’s from other dementias or neurodegenerative conditions, making it a valuable tool in early diagnosis, treatment planning, and monitoring disease progression.

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Taurine

Urine

Amino Acids; Urine 24-hour (Doctor's Data), Doctor's Data

Optimal range:   350 - 1850 qmol/24 hours

Taurine is a crucial amino acid that serves multiple roles in the body:

(1) It acts as a powerful antioxidant, helping to protect cells from damage caused by harmful molecules known as free radicals.

(2) Taurine also aids in the regulation of minerals such as calcium within cells

(3) and supports the healthy function of the heart and blood vessels.

(4) Additionally, it is vital for the proper functioning of the brain and eyes.

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Taurine

Blood

NutriStat Basic Profile, US BioTek

Optimal range:   89.9 - 301 umol/L

Taurine differs from other amino acids because a sulfur group replaces the carboxyl group of what would be the nonessential amino acid, β-alanine. It takes part in biochemical reactions and is not fully incorporated into proteins. In most tissues, it remains a free amino acid.

Taurine’s highest concentration is in muscle, platelets, and the central nervous system. Taurine is mainly obtained via dietary sources (dairy, shellfish, turkey, energy drinks), but can also come from sulfur amino acid metabolism (methionine and cysteine).

It has been proposed that taurine acts as an antioxidant, intracellular osmolyte, membrane stabilizer, and a neurotransmitter.

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Taurine

Urine

Neuro Basic Profile (Labrix, Doctor's Data), Doctor's Data

Optimal range:   320 - 1000 umol/g

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TAURINE

Urine

Amino Acid Analysis, LC/MS, Quest Diagnostics

Optimal range:   0 - 269 mmol/mol creatinine

Taurine differs from other amino acids because a sulfur group replaces the carboxyl group of what would be the nonessential amino acid, β-alanine. It takes part in biochemical reactions and is not fully incorporated into proteins. In most tissues, it remains a free amino acid.

Taurine’s highest concentration is in muscle, platelets, and the central nervous system. Taurine is mainly obtained via dietary sources (dairy, shellfish, turkey, energy drinks), but can also come from sulfur amino acid metabolism (methionine and cysteine).

It has been proposed that taurine acts as an antioxidant, intracellular osmolyte, membrane stabilizer, and a neurotransmitter.

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Taurine

OMX Organic Metabolomics / Diagnostic Solutions, Diagnostic Solutions Laboratory

Optimal range:   39.2 - 2436.6 nmol/mg Creatinine

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Taurine

Methylation Panel, Genova Diagnostics

Optimal range:   50 - 139 micromol/L

Taurine differs from other amino acids because a sulfur group replaces the carboxyl group of what would be the non-essential amino acid, β-alanine. It takes part in biochemical reactions and is not fully incorporated into proteins. In most tissues, it remains a free amino acid. Taurine’s highest concentration is in muscle, platelets, and the central nervous system. Taurine is mainly obtained via dietary sources (dairy, shellfish, turkey, energy drinks), but can also come from sulfur amino acid metabolism (methionine and cysteine). [L], [L]

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Taurine

Neurotransmitters

Optimal range:   52 - 1025 uMol/gCr

Taurine important for proper heart function, healthy sleep and promoting calmness.

Taurine is an amino sulfonic acid, but it is often referred to as an amino acid, a chemical that is a required building block of protein. Taurine is found in large amounts in the brain, retina, heart, and blood cells called platelets. 

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Taurine

Amino Acid Analysis, Quest Diagnostics

Optimal range:   31 - 102 umol/L

Taurine differs from other amino acids because a sulfur group replaces the carboxyl group of what would be the nonessential amino acid, β-alanine. It takes part in biochemical reactions and is not fully incorporated into proteins. In most tissues, it remains a free amino acid.

Taurine’s highest concentration is in muscle, platelets, and the central nervous system. Taurine is mainly obtained via dietary sources (dairy, shellfish, turkey, energy drinks), but can also come from sulfur amino acid metabolism (methionine and cysteine).

It has been proposed that taurine acts as an antioxidant, intracellular osmolyte, membrane stabilizer, and a neurotransmitter.

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Taurine

Amino Acid Profile, Qn (Urine), LabCorp

Optimal range:   24.2 - 5335.7 umol/g Cr

Taurine differs from other amino acids because a sulfur group replaces the carboxyl group of what would be the nonessential amino acid, β-alanine. It takes part in biochemical reactions and is not fully incorporated into proteins. In most tissues, it remains a free amino acid.

Taurine’s highest concentration is in muscle, platelets, and the central nervous system. Taurine is mainly obtained via dietary sources (dairy, shellfish, turkey, energy drinks), but can also come from sulfur amino acid metabolism (methionine and cysteine).

It has been proposed that taurine acts as an antioxidant, intracellular osmolyte, membrane stabilizer, and a neurotransmitter.

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Taurine

3102 ION (Blood/Urine) Amino Acids 40, Genova Diagnostics

Optimal range:   4.41 - 10.99 qmol/dL

Taurine differs from other amino acids because a sulfur group replaces the carboxyl group of what would be the nonessential amino acid, β-alanine. It takes part in biochemical reactions and is not fully incorporated into proteins. In most tissues, it remains a free amino acid.

Taurine’s highest concentration is in muscle, platelets, and the central nervous system. Taurine is mainly obtained via dietary sources (dairy, shellfish, turkey, energy drinks), but can also come from sulfur amino acid metabolism (methionine and cysteine).

It has been proposed that taurine acts as an antioxidant, intracellular osmolyte, membrane stabilizer, and a neurotransmitter.

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Taurine

Amino Acids test [Great Plains Laboratory / Doctor's Data], Doctor's Data

Optimal range:   200 - 1400 qM/g creatinine

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Taurine

Amino Acid Profile, Qn (Plasma), LabCorp

Optimal range:   29.2 - 132.3 umol/L

Taurine is a sulfur-containing amino acid required for bile formation.

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Taurine

ZRT Laboratory (Urinary Neurotransmitters), ZRT Laboratory

Optimal range:   24.5 - 134.1 µg/g creatinine

Taurine improves sleep, relieves anxiety, and has neuroprotective properties.

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Taurine

NutrEval Plasma - Urine and Blood, Genova Diagnostics

Optimal range:   4.41 - 10.99 Units

Taurine differs from other amino acids because a sulfur group replaces the carboxyl group of what would be the nonessential amino acid, β-alanine. It takes part in biochemical reactions and is not fully incorporated into proteins.

In most tissues, it remains a free amino acid. Taurine’s highest concentration is in muscle, platelets, and the central nervous system.

Taurine is mainly obtained via dietary sources (dairy, shellfish, turkey, energy drinks), but can also come from sulfur amino acid metabolism (methionine and cysteine).

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Taurine

Metabolimix+, Genova Diagnostics

Optimal range:   39 - 568 micromol/g creatinine

Taurine differs from other amino acids because a sulfur group replaces the carboxyl group of what would be the nonessential amino acid, β-alanine. It takes part in biochemical reactions and is not fully incorporated into proteins. In most tissues, it remains a free amino acid.

Taurine’s highest concentration is in muscle, platelets, and the central nervous system. Taurine is mainly obtained via dietary sources (dairy, shellfish, turkey, energy drinks), but can also come from sulfur amino acid metabolism (methionine and cysteine).

It has been proposed that taurine acts as an antioxidant, intracellular osmolyte, membrane stabilizer, and a neurotransmitter.

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Taurine (Plasma)

OMX Organic Metabolomics / Diagnostic Solutions, Diagnostic Solutions Laboratory

Optimal range:   25.9 - 107.2 nmol/ML

Taurine differs from other amino acids because a sulfur group replaces the carboxyl group of what would be the nonessential amino acid, β-alanine. It takes part in biochemical reactions and is not fully incorporated into proteins. In most tissues, it remains a free amino acid.

Taurine’s highest concentration is in muscle, platelets, and the central nervous system. Taurine is mainly obtained via dietary sources (dairy, shellfish, turkey, energy drinks), but can also come from sulfur amino acid metabolism (methionine and cysteine).

It has been proposed that taurine acts as an antioxidant, intracellular osmolyte, membrane stabilizer, and a neurotransmitter.

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Taurine (Plasma)

Amino Acids 40 Profile, Genova Diagnostics

Optimal range:   29 - 136 µmol/L , 2.90 - 13.60 µmol/dL

Taurine is a sulfur-containing amino acid required for bile formation.

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Taurine (Urine)

Amino Acids Analysis, Genova Diagnostics

Optimal range:   21 - 424 micromol/g creatinine

Taurine is a sulfur-containing amino acid required for bile formation.

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TB1-NIL

Immune System

Optimal range:   0 - 0.35 IU/ml

The TB1-NIL biomarker is integral to the QuantiFERON-TB Gold Plus (QFT-Plus) assay, a diagnostic tool used to detect Mycobacterium tuberculosis infection. In this context, 'NIL' refers to the baseline interferon-gamma (IFN-γ) level measured without antigen stimulation, serving as a negative control to account for non-specific background activity. The TB1 tube contains antigens that primarily stimulate CD4+ T-cell responses. By subtracting the NIL value from the TB1-stimulated IFN-γ level (TB1-NIL), clinicians can assess the specific immune response to TB antigens. A TB1-NIL value of 0.35 IU/mL or higher typically indicates a positive result, suggesting a TB infection. This method enhances the accuracy of TB diagnosis by distinguishing specific immune responses from background noise.

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