Explore our database of over 10000 laboratory markers.

Search and Understand 10000 Biomarkers

StoneRisk Diagnostic Profile

Optimal range:   12 - 293 mg/24 hr

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Malate

Urine

Organic Acids Profile (US BioTek), US BioTek

Optimal range:   0 - 2.62 ug/mg creatinine

Malate is involved in the citric acid cycle (aka. Krebs cycle). The citric acid cycle is a series of reactions that occur in the mitochondrion to generate chemical energy that fuels the metabolism.

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Organix Comprehensive Profile - Urine, Genova Diagnostics

Optimal range:   0 - 3.1 mcg/mg creatinine

Malate is involved in the citric acid cycle (aka. Krebs cycle). The citric acid cycle is a series of reactions that occur in the mitochondrion to generate chemical energy that fuels the metabolism.

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3301 Organix Comprehensive Profile - Urine (mmol/mol creatinine), Genova Diagnostics

Optimal range:   0 - 3 mmol/mol creatinine

Malate is involved in the citric acid cycle (aka. Krebs cycle). The citric acid cycle is a series of reactions that occur in the mitochondrion to generate chemical energy that fuels the metabolism.

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2200 GI Effects Comprehensive Profile - Stool, Genova Diagnostics

Optimal range:   0 - 2 Score

Biomarkers:

Products of Protein Breakdown - Products of Protein Breakdown are markers of undigested protein reaching the colon.

Pancreatic Elastase - Pancreatic Elastase-1 is a marker of exocrine pancreatic function.

Fecal Fats - Fecal Fat is a marker of fat breakdown and absorption.

Score explanation:

The functional imbalance scores are generated using weighted algorithms that incorporate biomarkers belonging to each functional category. 

0 to 2: This represents a low need for support.

2 to 3: This represents an optional need for support.

4 to 6: This represents moderate need for support.

7 to 10: This represents high need for support.

Therapeutic Support Options: 

Therapeutic support options are static to serve as potential treatment ideas. Clinician discretion is advised when selecting appropriate therapeutics for individual patients.

- Digestive Enzymes

- Betaine HCl

- Bile Salts

- Apple Cider Vinegar

- Mindful Eating Habits

- Digestive Bitters

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Organic Acids Test (OAT) - Nutritional and Metabolic Profile, Mosaic Diagnostics

Optimal range:   0.06 - 1.8 mmol/mol creatinine

Malic Acid is involved in the citric acid cycle (aka. Krebs cycle). The citric acid cycle is a series of reactions that occur in the mitochondrion to generate chemical energy that fuels the metabolism.

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Organic Acids, Comprehensive, Quantitative, Quest Diagnostics

Optimal range:   0 - 3 mmol/mol creatinine

Fumaric acid uses the fumarase enzyme to become malic acid. Malate dehydrogenase catalyzes the conversion of malic acid into oxaloacetate. Two forms of this enzyme exist in eukaryotes. One operates within the mitochondria to contribute to the Citric Acid Cycle; the other is in the cytosol where it participates in the malate/ aspartate shuttle. Riboflavin is an important cofactor for this enzyme and overall mitochondrial energy production and cellular function. At the end of each Citric Acid Cycle, the four-carbon oxaloacetate has been regenerated, and the cycle continues.

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Organic Acids Test (OAT) - Nutritional and Metabolic Profile, Mosaic Diagnostics

Optimal range:   0 - 1.1 mmol/mol creatinine

Malic Acid is involved in the citric acid cycle (aka. Krebs cycle). The citric acid cycle is a series of reactions that occur in the mitochondrion to generate chemical energy that fuels the metabolism.

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Organic Acids Test (OAT) - Nutritional and Metabolic Profile, Mosaic Diagnostics

Optimal range:   0 - 2.3 mmol/mol creatinine

Malic Acid is involved in the citric acid cycle (aka. Krebs cycle). The citric acid cycle is a series of reactions that occur in the mitochondrion to generate chemical energy that fuels the metabolism.

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NutriStat Basic Profile, US BioTek

Optimal range:   0 - 3.59 ug/mgCR

Fumaric acid uses the fumarase enzyme to become malic acid. Malate dehydrogenase catalyzes the conversion of malic acid into oxaloacetate. Two forms of this enzyme exist in eukaryotes. One operates within the mitochondria to contribute to the Citric Acid Cycle; the other is in the cytosol where it participates in the malate/ aspartate shuttle. Riboflavin is an important cofactor for this enzyme and overall mitochondrial energy production and cellular function. At the end of each Citric Acid Cycle, the four-carbon oxaloacetate has been regenerated, and the cycle continues.

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OMX Organic Metabolomics / Diagnostic Solutions, Diagnostic Solutions Laboratory | GI-MAP & Food Sensitivity Tests

Optimal range:   1 - 27.1 nmol/mg Creatinine

Malic Acid is involved in the citric acid cycle (aka. Krebs cycle). The citric acid cycle is a series of reactions that occur in the mitochondrion to generate chemical energy that fuels the metabolism.

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Metabolimix+, Genova Diagnostics

Optimal range:   0 - 3 mmol/mol creatinine

Fumaric acid uses the fumarase enzyme to become malic acid. Malate dehydrogenase catalyzes the conversion of malic acid into oxaloacetate. Two forms of this enzyme exist in eukaryotes. One operates within the mitochondria to contribute to the Citric Acid Cycle; the other is in the cytosol where it participates in the malate/ aspartate shuttle. Riboflavin is an important cofactor for this enzyme and overall mitochondrial energy production and cellular function. At the end of each Citric Acid Cycle, the four-carbon oxaloacetate has been regenerated, and the cycle continues.

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Organic Acids, Vibrant Wellness

Optimal range:   0.08 - 1.74 mmol/mol

Fumaric acid uses the fumarase enzyme to become malic acid. Malate dehydrogenase catalyzes the conversion of malic acid into oxaloacetate. Two forms of this enzyme exist in eukaryotes. One operates within the mitochondria to contribute to the Citric Acid Cycle; the other is in the cytosol where it participates in the malate/ aspartate shuttle.

Riboflavin is an important cofactor for this enzyme and overall mitochondrial energy production and cellular function. Riboflavin (also known as vitamin B2) is one of the B vitamins, which are all water soluble.

At the end of each Citric Acid Cycle, the four-carbon oxaloacetate has been regenerated, and the cycle continues.

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Metabolic Analysis Markers (Urine)

Optimal range:   0 - 3 mmol/mol creatinine

Malic Acid is involved in the citric acid cycle (aka. Krebs cycle). The citric acid cycle is a series of reactions that occur in the mitochondrion to generate chemical energy that fuels the metabolism.

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Organic Acids Test (OAT) - Nutritional and Metabolic Profile, Mosaic Diagnostics

Optimal range:   0 - 9.7 mmol/mol creatinine

Malonic acid is found to be associated with malonyl-CoA decarboxylase deficiency, which is an inborn error of metabolism. The name “Malonic” originates from Latin malum, meaning apple. Malonic acid is the archetypal example of a competitive inhibitor: it acts against succinate dehydrogenase (complex II) in the respiratory electron transport chain. 

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Organic Acids, Comprehensive, Quantitative, Quest Diagnostics

Optimal range:   0 - 0 mmol/mol creatinine

Malonic acid is found to be associated with malonyl-CoA decarboxylase deficiency, which is an inborn error of metabolism. The name “Malonic” originates from Latin malum, meaning apple. Malonic acid is the archetypal example of a competitive inhibitor: it acts against succinate dehydrogenase (complex II) in the respiratory electron transport chain. 

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Organic Acids Test (OAT) - Nutritional and Metabolic Profile, Mosaic Diagnostics

Optimal range:   0 - 9.9 mmol/mol creatinine

Malonic acid is found to be associated with malonyl-CoA decarboxylase deficiency, which is an inborn error of metabolism. The name “Malonic” originates from Latin malum, meaning apple. Malonic acid is the archetypal example of a competitive inhibitor: it acts against succinate dehydrogenase (complex II) in the respiratory electron transport chain. 

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