The Thyrotropin Receptor Ab test detects the autoantibody that's associated with Graves' disease. An antibody is a specialized protein made by your immune system. Antibodies are custom made to kill pathogens in your body, such as viruses or bacteria.

Thyrotropin is also called thyroid-stimulating hormone, or TSH. TSH binds to receptors on the thyroid gland to tell it to produce thyroid hormone. The thyrotropin receptor antibody mimics TSH, so when it's present, it directs the thyroid to keep releasing hormone when your body doesn't need it. That results in high levels of thyroid hormones, which is what causes symptoms. If the thyrotropin receptor antibody is present, it's an indicator of Graves' disease.

Thyroid-binding globulin (TBG) is produced in the liver and is the primary circulating (transport) protein that binds thyroid hormones3,5,3’-triiodothyronine (T3) and thyroxine (T4) and carries them in the bloodstream.

Thyroid-binding globulin (TBG) is produced in the liver and is the primary circulating (transport) protein that binds thyroid hormones3,5,3’-triiodothyronine (T3) and thyroxine (T4) and carries them in the bloodstream.

Tiglylglycine is a marker for mitochondrial dysfunction. Mutations of mitochondria DNA may result from exposure to toxic chemicals, infections, inflammation, and nutritional deficiencies.

SOURCES:

Found in manufacturing, food, packaging, solder, bronzing, dyeing textiles, plastics, PVC pipes, fungicides, toothpaste, perfume, soap, food additives, electronic, cigarette aerosol, and dyes. Naturally present and rocks and nearby air, water, and soil. Seafood is the primary route of human exposure to tin compounds. Tin is found in both organic and inorganic forms. Inorganic tin is generally regarded as safe by the FDA as a food additive for human consumption.

Nutrient interactions:

Tin disturbs copper, zinc, and iron metabolism.

SOURCES:

Found in manufacturing, food, packaging, solder, bronzing, dyeing textiles, plastics, PVC pipes, fungicides, toothpaste, perfume, soap, food additives, electronic, cigarette aerosol, and dyes. Naturally present and rocks and nearby air, water, and soil. Seafood is the primary route of human exposure to tin compounds. Tin is found in both organic and inorganic forms. Inorganic tin is generally regarded as safe by the FDA as a food additive for human consumption.

Nutrient interactions:

Tin disturbs copper, zinc, and iron metabolism.

Hair Tin (Sn) levels have been found to correlate with environmental exposure. Depending on chemical form, Sn is a potentially toxic element. Inorganic Sn has a low degree of toxicity, while organic Sn has appreciable toxicity. Inorganic Sn is used as flame-proofing treatment in textiles, as a wood preservative, and has various uses in the glass industry. Sn is also used in tin plate electrolysis for Sn alloy coatings.

Urinary tin (Sn) provides an indication of recent or ongoing exposure to the metal, and endogenous detoxification to a lesser extent. Sn has no known physiological function in the body. Inorganic Sn has a low potential for toxicity, while organic Sn may have appreciable toxic effects.

Metallic Sn and inorganic Sn compounds are normally found in small amounts in soil, food and air. Exposure to Sn compounds may be much higher in close proximity to hazardous waste sites. Inorganic Sn is poorly absorbed from the gut. The main source of Sn is food. Canned tomatoes, tomato products, pineapple, pears and similar fruits contain the highest concentrations of Sn. The Sn concentrations of food increase with storage in opened cans.

Sources of exposure:

Toothpastes, perfumes, soaps, food additives and dyes, plastics, food packages, plastic pipes, pesticides, paints, and pest repellents; air, water, and soil near places where naturally present in rocks.

Health Effects:

Stomach ache, anemia, liver and kidney problems, reproduction, skin and eye irritation, affects brain and nervous system

A tissue transglutaminase (tTG) IgA and/or IgG test is used as part of an evaluation for certain autoimmune conditions, most notably celiac disease.

An autoimmune disease can occur when the body’s immune system mistakenly perceives a nonthreatening substance. In the case of people with celiac disease, gluten (a protein found in wheat, barley, rye, and oats) is seen as a foreign invader and is attacked by the immune system. This immune system response in celiac disease also involves the production of antibodies directed against an enzyme normally present in the intestines called tissue transglutaminase (tTG).