Explore our database of over 4000 laboratory markers.

Search and Understand 4000+ Biomarkers

Isocitrate

3301 Organix Comprehensive Profile - Urine (mmol/mol creatinine), Genova Diagnostics

Optimal range:   22 - 65 mmol/mol creatinine

Citric acid, cis-aconitic acid, and isocitric acid are the first three metabolites in the Krebs Citric Acid energy production cycle, which operates in the mitochondria of your cells. 

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Isocitrate

Urine

Organic Acids Profile (US BioTek), US BioTek

Optimal range:   19.94 - 74.88 ug/mg creatinine

Citric acid, cis-aconitic acid, and isocitric acid are the first three metabolites in the Krebs Citric Acid energy production cycle, which operates in the mitochondria of your cells. 

Citrate, cis-Aconitate (and Isocitrate) are involved in both energy production and removal of toxic ammonia.

High levels can indicate ammonia toxicity. Chronic loss of these valuable compounds can contribute to loss of organ reserve and disturbances in neurological function. If they are low they can indicate a need for essential amino acids, especially arginine.

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Isocitric

Organic Acids, Comprehensive, Quantitative, Quest Diagnostics

Optimal range:   10 - 131 mmol/mol creatinine

A two-carbon group from Acetyl-CoA is transferred to oxaloacetate to form citric acid. Citric acid is then converted to isocitric acid through a cis-aconitic intermediate using the enzyme aconitase. Aconitase is an iron-sulfate protein that controls iron homeostasis.

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Isocitric Acid

Urine

NutriStat Basic Profile, US BioTek

Optimal range:   19 - 79.2 ug/mgCR

A two-carbon group from Acetyl-CoA is transferred to oxaloacetate to form citric acid. Citric acid is then converted to isocitric acid through a cis-aconitic intermediate using the enzyme aconitase. Aconitase is an iron-sulfate protein that controls iron homeostasis.

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Isocitric Acid

OMX Organic Metabolomics / Diagnostic Solutions, Diagnostic Solutions Laboratory

Optimal range:   137.1 - 794.9 nmol/mg Creatinine

Citric acid, cis-aconitic acid, and isocitric acid are the first three metabolites in the Krebs Citric Acid energy production cycle, which operates in the mitochondria of your cells. 

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Isocitric Acid

Organic Acids Metabolomic Mapping, NutriPATH

Optimal range:   35 - 143 ug/mgCR

Citric acid, cis-aconitic acid, and isocitric acid are the first three metabolites in the Krebs Citric Acid energy production cycle, which operates in the mitochondria of your cells. 

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Isocitric Acid

Metabolimix+, Genova Diagnostics

Optimal range:   22 - 65 mmol/mol creatinine

A two-carbon group from Acetyl-CoA is transferred to oxaloacetate to form citric acid. Citric acid is then converted to isocitric acid through a cis-aconitic intermediate using the enzyme aconitase. Aconitase is an iron-sulfate protein that controls iron homeostasis.

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Isocitric Acid

Metabolic Analysis Markers (Urine)

Optimal range:   22 - 65 mmol/mol creatinine

Citric acid, cis-aconitic acid, and isocitric acid are the first three metabolites in the Krebs Citric Acid energy production cycle, which operates in the mitochondria of your cells. 

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Isocyanate IgG+IgA

Array 11 – Chemical Immune Reactivity Screen, Cyrex Laboratories

Optimal range:   0.2 - 1.5 ELISA Index

Isocyanates are a family of highly reactive, low molecular weight chemicals.

Exposure to toluene diisocyanate (TDI) and other isocyanates can cause irritation of the mucous membranes, eyes, upper respiratory tract, and skin.

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Isocyanate IgM

Array 11 – Chemical Immune Reactivity Screen, Cyrex Laboratories

Optimal range:   0.2 - 2.1 ELISA Index

Isocyanates are a family of highly reactive, low molecular weight chemicals.

Exposure to toluene diisocyanate (TDI) and other isocyanates can cause irritation of the mucous membranes, eyes, upper respiratory tract, and skin.

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Isoleucine

Amino Acids test [Great Plains Laboratory / Doctor's Data], Doctor's Data

Optimal range:   5 - 30 qM/g creatinine

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Isoleucine

Amino Acid Profile, Qn (Plasma), LabCorp

Optimal range:   32.8 - 88.3 umol/L

Isoleucine is one of the three branched-chain amino acids (BCAAs) alongside both leucine and valine.

Isoleucine is a common component of proteins, peptides and hormones. Leucine is catabolized as a source of carbon for energy production during exercise in skeletal muscle.

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Isoleucine

NutrEval Plasma - Urine and Blood, Genova Diagnostics

Optimal range:   4.09 - 17.43 Units

Branched Chain Amino Acids (Isoleucine, Leucine, Valine) are the three branched chain amino acids (BCAAs).

Branched chain amino acids (BCAA) are essential amino acids and must be obtained from the diet (mainly meat, grains, and dairy). 

Not only do the BCAAs account for almost 50% of muscle protein, but they have many metabolic functions. 

BCAAs act as substrates for protein synthesis, energy production, neurotransmitter production, glucose metabolism, and the immune response. They are also involved in stimulation of albumin and glycogen synthesis, improvement of insulin resistance, inhibition of free radical production, and hepatocyte apoptosis with liver regeneration.

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Isoleucine

Metabolimix+, Genova Diagnostics

Optimal range:   3 - 25 micromol/g creatinine

Branched Chain Amino Acids (Isoleucine, Leucine, Valine) are the three branched chain amino acids (BCAAs). Branched chain amino acids (BCAA) are essential amino acids and must be obtained from the diet (mainly meat, grains, and dairy).

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Isoleucine

Amino Acid Analysis, Quest Diagnostics

Optimal range:   34 - 98 umol/L

Branched Chain Amino Acids (Isoleucine, Leucine, Valine) are the three branched chain amino acids (BCAAs). Branched chain amino acids (BCAA) are essential amino acids and must be obtained from the diet (mainly meat, grains, and dairy).

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Isoleucine

Amino Acid Profile, Qn (Urine), LabCorp

Optimal range:   5 - 48.1 umol/g Cr

Branched Chain Amino Acids (Isoleucine, Leucine, Valine) are the three branched chain amino acids (BCAAs).

Branched chain amino acids (BCAA) are essential amino acids and must be obtained from the diet (mainly meat, grains, and dairy). 

Not only do the BCAAs account for almost 50% of muscle protein, but they have many metabolic functions. 

BCAAs act as substrates for protein synthesis, energy production, neurotransmitter production, glucose metabolism, and the immune response. They are also involved in stimulation of albumin and glycogen synthesis, improvement of insulin resistance, inhibition of free radical production, and hepatocyte apoptosis with liver regeneration.

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Isoleucine

3102 ION (Blood/Urine) Amino Acids 40, Genova Diagnostics

Optimal range:   4.09 - 17.43 qmol/dL

Branched Chain Amino Acids (Isoleucine, Leucine, Valine) are the three branched chain amino acids (BCAAs). Branched chain amino acids (BCAA) are essential amino acids and must be obtained from the diet (mainly meat, grains, and dairy).

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ISOLEUCINE

Urine

Amino Acid Analysis, LC/MS, Quest Diagnostics

Optimal range:   0 - 4 mmol/mol creatinine

Branched Chain Amino Acids (Isoleucine, Leucine, Valine) are the three branched chain amino acids (BCAAs). Branched chain amino acids (BCAA) are essential amino acids and must be obtained from the diet (mainly meat, grains, and dairy).

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Isoleucine

Male Comprehensive Metabolic Performance Profile (Urine) Physicians Lab, Physicians Lab

Optimal range:   447.7 - 1211.3 ng/mg CR

Branched Chain Amino Acids (Isoleucine, Leucine, Valine) are the three branched chain amino acids (BCAAs). Branched chain amino acids (BCAA) are essential amino acids and must be obtained from the diet (mainly meat, grains, and dairy).

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Isoleucine

Urine

Amino Acids; Urine 24-hour (Doctor's Data), Doctor's Data

Optimal range:   6 - 32 qmol/24 hours

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