Immature Grans (Abs)

Other names: Immature Granulocytes (Absolute)

check icon Optimal Result: 0 - 0.1 x10E3/µL.

Immature granulocytes (IGs) are precursor white blood cells that appear in the bloodstream during heightened immune responses, particularly in severe infections or inflammatory conditions. Their presence in a complete blood count (CBC) provides valuable diagnostic information about immune system activity.

What Are Immature Granulocytes?

Granulocytes are a subset of white blood cells containing enzyme-filled granules used to combat pathogens. The three main types are:

- Neutrophils

- Eosinophils

- Basophils

Immature granulocytes are the underdeveloped forms of these cells. In healthy individuals, IGs are typically absent or present at very low levels. Their appearance indicates accelerated bone marrow production and release of white blood cells, often in response to:

- Infections

- Inflammation

- Bone marrow stressors

Clinical Significance

Elevated IG counts serve as an important marker for early detection of various conditions:

- Bacterial infections

- Sepsis

- Inflammatory disorders

- Certain cancers

An increased IG level signifies an active immune response, potentially indicating an underlying health issue.

Indications for Testing

IG count is a crucial parameter in CBC tests, especially for immunocompromised patients. Testing is frequently recommended for:

- Chemotherapy patients

- Individuals with HIV/AIDS

- ICU patients

- Those suspected of severe infection or sepsis

Interpreting IG Levels

The normal reference range for IGs is typically <2%. Values exceeding this threshold suggest a severe immune response or ongoing bone marrow activity.

White Blood Cell Type Normal Range (%) Normal Range (×10-9/l)
Neutrophils 40–80 2.0–7.0
Lymphocytes 20–40 1.0–3.0
Monocytes 2–10 0.2–1.0
Eosinophils 1–6 0.02–0.5
Basophils <1–2 0.02–0.1

 

Importance of IG Testing

Monitoring IG levels is crucial for:

- Assessing immune response severity

- Guiding treatment decisions

- Enabling timely interventions in critical situations like sepsis or severe inflammation

Early detection of elevated IG levels can significantly improve patient outcomes by prompting rapid medical intervention.

Keywords: immature granulocytes, IG biomarker, infection detection, bone marrow activity, sepsis monitoring, neonatal hematology, immune response markers, peripheral blood analysis

What does it mean if your Immature Grans (Abs) result is too high?

Understanding Elevated Immature Granulocytes (IG) Levels

Immature granulocytes (IG) in peripheral blood serve as a valuable biomarker for diagnosing and monitoring various medical conditions. Typically low or undetectable in healthy individuals, elevated IG levels often indicate underlying health issues.

Clinical Significance of Immature Granulocytes

Immature granulocytes, including promyelocytes, myelocytes, and metamyelocytes, are precursors to mature white blood cells. Their presence in peripheral blood signifies an early immune response, reflecting increased bone marrow activity in reaction to perceived threats. The IG count serves as an early marker for:

- Infection

- Inflammation

- Other marrow-stimulating events

While IG levels can aid in detecting severe conditions like sepsis, they should not be used as a sole diagnostic criterion.

Several conditions can lead to increased IG levels:

  1. Bacterial infections
  2. Acute inflammatory disorders
  3. Cancer and bone marrow metastasis
  4. Tissue necrosis (e.g., myocardial infarction, severe trauma)
  5. Acute transplant rejection
  6. Surgical and orthopedic trauma
  7. Myeloproliferative neoplasms
  8. Steroid use
  9. Pregnancy

Special Considerations in IG Monitoring

Neonates and Children

Premature infants and newborns under seven days old may exhibit higher IG levels due to immature immune systems. Interpretation requires caution in this population.

Elderly Patients

Older adults may show elevated IG levels without a corresponding increase in neutrophils, complicating diagnosis. This can result from age-related changes in bone marrow function or myelosuppressive conditions.

Patients with Myelosuppression (Bone marrow suppression)

Individuals undergoing chemotherapy or with bone marrow suppression may display increased IG counts even without infection or inflammation, necessitating careful clinical evaluation.

Limitations of IG Measurement

While valuable, IG count should not be used as a standalone diagnostic tool. It should be considered alongside other laboratory markers such as:

IG measurement is particularly useful for monitoring treatment effectiveness rather than as a primary diagnostic marker.

Elevated immature granulocyte levels in peripheral blood indicate an early-stage response to various stimuli. While offering promising diagnostic value, IG measurement should be interpreted cautiously, considering factors such as:

- Age

- Medical history

- Concurrent treatments

A comprehensive understanding of IG count variations can aid clinicians in making informed decisions for diagnosing and managing diverse health conditions.

All Your Lab Results.
One Simple Dashboard.

What does it mean if your Immature Grans (Abs) result is too low?

There is no health issue associated with low granulocyte counts.

Laboratories

Bring All Your Lab Results Together — In One Place

We accept reports from any lab, so you can easily collect and organize all your health information in one secure spot.

lab corp logo
genova diagnostics logo
quest diagnostics logo
dutch test logo
doctors data logo
vibrant america logo
diagnostic solutions logo
zrt laboratory logo
the great plains laboratory logo
cyrex laboratories logo
spectracell logo

Pricing Table

decoration

Personal plans

$15/ month

Complete Plan

Access your lab reports, explanations, and tracking tools.

  • Import lab results from any provider
  • Track all results with visual tools
  • Customize your reference ranges
  • Export your full lab history anytime
  • Share results securely with anyone
  • Begin with first report entered
  • Cancel or upgrade anytime

$250/ once

Unlimited Account

Pay once, access everything—no monthly fees, no limits.

  • Import lab results from any provider
  • Track all results with visual tools
  • Customize your reference ranges
  • Export your full lab history anytime
  • Share results securely with anyone
  • Receive 10 reports entered for you
  • Skip the $15/month subscription — no recurring payments ever

$45/ month

Pro Monthly

Designed for professionals managing their clients' lab reports

  • Import lab results from any provider
  • Track lab results for multiple clients
  • Customize reference ranges per client
  • Export lab histories and reports
  • Begin with first report entered by us
  • Cancel or upgrade anytime

About membership

What's included in a Healthmatters membership

microscope icon Import Lab Results from Any Source

person icon See Your Health Timeline

book icon Understand What Your Results Mean

textbook icon

textbook icon Visualize Your Results

folder icon

folder icon

card icon Securely Share With Anyone You Trust

Let Your Lab Results Tell the Full Story

What Healthmatters Members Are Saying

5 stars rating

I have been using Healthmatters.io since 2021. I travel all over the world and use different doctors and health facilities. This site has allowed me to consolidate all my various test results over 14 years in one place. And every doctor that I show this to has been impressed. Because with  any health professional I talk to, I can pull up historical results in seconds. It is invaluable. Even going back to the same doctor, they usually do not have the historical results from their facility in a graph format. That has been very helpful.

Anthony

Unlimited Plan Member since 2021

5 stars rating

What fantastic service and great, easy-to-follow layouts! I love your website; it makes it so helpful to see patterns in my health data. It's truly a pleasure to use. I only wish the NHS was as organized and quick as Healthmatters.io. You've set a new standard for health tracking!

Karin

Advanced Plan Member since 2020

5 stars rating

As a PRO member and medical practitioner, Healthmatters.io has been an invaluable tool for tracking my clients' data. The layout is intuitive, making it easy to monitor trends and spot patterns over time. The ability to customize reports and charts helps me present information clearly to my clients, improving communication and outcomes. It's streamlined my workflow, saving me time and providing insights at a glance. Highly recommended for any practitioner looking for a comprehensive and user-friendly solution to track patient labs!

Paul

Healthmatters Pro Member since 2024

Use promo code to save 10% off any plan.

Frequently asked questions

Healthmatters is a personal health dashboard that helps you organize and understand your lab results. It collects and displays your medical test data from any lab in one secure, easy-to-use platform.

  • Individuals who want to track and understand their health over time.
  • Health professionals, such as doctors, nutritionists, and wellness coaches, need to manage and interpret lab data for their clients.

With a Healthmatters account, you can:

  • Upload lab reports from any lab
  • View your data in interactive graphs, tables, and timelines
  • Track trends and monitor changes over time
  • Customize your reference ranges
  • Export and share your full lab history
  • Access your results anytime, from any device

Professionals can also analyze client data more efficiently and save time managing lab reports.

Healthmatters.io personal account provides in-depth research on 4000+ biomarkers, including information and suggestions for test panels such as, but not limited to:

  • The GI Effects® Comprehensive Stool Profile,
  • GI-MAP,
  • The NutrEval FMV®,
  • The ION Profile,
  • Amino Acids Profile,
  • Dried Urine Test for Comprehensive Hormones (DUTCH),
  • Organic Acids Test,
  • Organix Comprehensive Profile,
  • Toxic Metals,
  • Complete Blood Count (CBC),
  • Metabolic panel,
  • Thyroid panel,
  • Lipid Panel,
  • Urinalysis,
  • And many, many more.

You can combine all test reports inside your Healthmatters account and keep them in one place. It gives you an excellent overview of all your health data. Once you retest, you can add new results and compare them.

If you are still determining whether Healthmatters support your lab results, the rule is that if you can test it, you can upload it to Healthmatters.

shield icon

We implement proven measures to keep your data safe.

At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.

gdpr compliance image hipaa compliance image