Adrenal reserve, represented by the marker THE+5α-THF+THF (tetrahydrocortisone, 5-alpha-tetrahydrocortisol, and tetrahydrocortisol) on a dried urine essential hormone profile, is a critical indicator of adrenal gland function, particularly in women during the luteal phase of their menstrual cycle. This phase, which occurs after ovulation and before menstruation, is characterized by significant hormonal fluctuations that can influence adrenal function. The adrenal reserve marker provides valuable insights into the body's ability to produce and metabolize cortisol, a vital stress hormone. Tetrahydrocortisone (THE), 5-alpha-tetrahydrocortisol (5α-THF), and tetrahydrocortisol (THF) are metabolites of cortisol and cortisone, and their levels in dried urine samples offer a non-invasive method to assess adrenal activity. Elevated levels of these metabolites may indicate heightened adrenal activity, which could be a response to chronic stress, illness, or other physiological demands. Conversely, low levels might suggest adrenal insufficiency or a reduced ability to cope with stress. This marker is particularly important in the context of the luteal phase, as hormonal imbalances during this period can exacerbate stress responses and impact overall health. Therefore, monitoring THE+5α-THF+THF levels can be instrumental in diagnosing adrenal disorders, guiding therapeutic interventions, and understanding the intricate relationship between menstrual cycle phases and adrenal health in women.
Low levels of the adrenal reserve markers THE+5α-THF+THF (tetrahydrocortisone, 5-alpha-tetrahydrocortisol, and tetrahydrocortisol) in a dried urine essential hormone profile can indicate adrenal insufficiency, a condition where the adrenal glands do not produce adequate amounts of stress hormones, particularly cortisol. This condition can manifest as chronic fatigue, weakness, and an inability to cope with stress. It is especially concerning in women during the luteal phase of their menstrual cycle, a time when the body naturally undergoes hormonal changes and may require a more robust adrenal response.
Treatment for low adrenal reserve often focuses on lifestyle changes and nutritional support. This can include stress reduction techniques such as yoga, meditation, or counseling to manage stressors more effectively. Adequate sleep and regular, moderate exercise are also beneficial. Nutritionally, a diet rich in vitamins and minerals, particularly B vitamins, vitamin C, zinc, and magnesium, supports adrenal function. Adaptogenic herbs like ashwagandha, rhodiola, and licorice root may be used under the guidance of a healthcare professional to help modulate the body's stress response.
In some cases, hormone replacement therapy may be necessary, but this should be approached cautiously and under strict medical supervision. It's important to work with a healthcare provider to develop a comprehensive treatment plan tailored to individual needs and hormone levels. Regular monitoring of adrenal function through follow-up testing is also crucial in managing and adjusting treatment over time.
Our specialized data entry service is designed to seamlessly integrate your laboratory results into your private dashboard. Just send in your lab test results—whether it's an image or a file—and our skilled data entry team will handle the rest. We accommodate various file formats like PDFs, JPGs, and Excel.
The first report is complimentary. After that, the data entry service is priced at $15 per report, unless it's part of your subscribed plan. It's an ideal solution whether you have numerous reports to upload or if your schedule doesn't permit self-data entry.
We strive to make the data entry process easy for you. Whether by offering dozens of templates to choose from that pre-populate the most popular laboratory panels or by giving you instant feedback on the entered values. Our data entry forms are an easy, fast, and convenient way to enter the reports yourself. There is no limit on how many lab reports you can upload.
track personal results
track multiple client's results
own it for life
for health professionals
for personal lab results
own it for life
Level up your lab report analysis with our Pro plan, built for health practitioners like you.
Health Business Account
Unlock additional Pro plans when you sign up.