Leukotriene E4 is a critical molecule in the field of immunology and inflammation. Its role in asthma, allergies, and potentially in other serious health conditions, underscores the importance of ongoing research in this area. Understanding the mechanisms of LTE4 not only contributes to better management of inflammatory diseases but also opens avenues for new therapeutic interventions in a variety of health disorders.

CD40 ligand (CD40L), also known as CD154, is a protein that is primarily expressed on the surface of activated T cells and belongs to a member of the tumor necrosis factor superfamily. Lack of CD40L results in an inability to undergo immunoglobulin class switch and only class IgM antibodies can be generated. CD40L exists as a membrane-bound form with a molecular weight of 33 kDa and as a soluble form with a molecular weight of 18 kDa. Soluble CD40L (sCD40L) is stored in platelet granules and thus its presence in the blood is a biomarker of platelet activation. sCD40L expression is known to be upregulated in atheroma-associated cells.

Lignoceric Acid is a saturated fatty acids, in particular it is part of the group of very long chain fatty acids (VLCFAs).

Lignoceric Acid is a saturated fatty acids, in particular it is part of the group of very long chain fatty acids (VLCFAs).

Lignoceric Acid is a saturated fatty acids, in particular it is part of the group of very long chain fatty acids (VLCFAs).

Lignoceric acid has 24 carbons and no double bonds (24:0). It can be formed from behenic acid using the elongase enzyme. It is found in peanuts, nut and seed oils. It can also be found in wood tar. Lignoceric acid is one of many fatty acids which compose brain tissue and myelin.

Limosilactobacillus reuteri is a lactic acid bacterium that naturally resides in the gastrointestinal tract of humans and other animals. It is considered a probiotic due to its potential health benefits, particularly in gastrointestinal health. In the context of a GI test, the presence of Limosilactobacillus reuteri can indicate its role in maintaining gut health and its potential therapeutic effects.

Linoleic acid is by far the most abundant polyunsaturated fatty acid in most human tissues. Linoleic acid is an essential fatty acid, and low levels indicate dietary insufficiency.

Linoleic acid is by far the most abundant polyunsaturated fatty acid in most human tissues. Linoleic acid is an essential fatty acid, and low levels indicate dietary insufficiency.

Linoleic acid (LA) is the only essential omega-6 fatty acid and must be obtained from the diet.

From LA, other omega-6s can be created using elongase and desaturase enzymes. LA contains 18 carbons, with 2 double bonds, the first of which is at the 6th carbon position (18:2n6).

LA is found in nuts and vegetable oils (corn, soybean, canola, sunflower, etc.) as well as most meats. When the double bonds of LA are arranged differently, the term conjugated LA (CLA) is used. Although technically CLA can be termed a trans-fat, a natural type of CLA can be obtained in the dietary intake of meat and milk from ruminant animals. There are many isomers of CLA – some beneficial and others are not as well defined. There is some controversy regarding how much LA is needed from the diet for adequacy. Although LA is needed to synthesize downstream fatty acids, it may lead to increased inflammatory fatty acid production.

LA/DGLA is a fatty acid ratio.

LA/DGLA stands for linolenic acid (=LA) and dihomogammalinolenic acid (=DGLA).

The LA/DGLA ratio is a biomarker that can indicate functional zinc deficiency.

LA/DGLA is a fatty acid ratio.

LA/DGLA stands for linolenic acid (=LA) and dihomogammalinolenic acid (=DGLA).

The LA/DGLA ratio is a biomarker that can indicate functional zinc deficiency.

Linoleic acid is by far the most abundant polyunsaturated fatty acid in most human tissues. Linoleic acid is an essential fatty acid, and low levels indicate dietary insufficiency.