Explore our database of over 10000 laboratory markers.

Search and Understand 10000 Biomarkers

Infectious Disease Profile

Optimal range:   0 - 0.9 / index

HSV Type 1-Specific Ab, IgG refers to the specific antibodies produced by the immune system in response to the herpes simplex virus type 1 (HSV-1). The IgG antibodies are indicative of a past or current infection with HSV-1. This test helps in diagnosing the presence of the virus, particularly in cases of oral herpes or cold sores.

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HSV 1/2 IgG/IgA/IgM antibodies, ArminLabs

Reference range:   Negative, Positive

The HSV-1/2 IgG ELISA detects type-specific IgG antibodies to herpes simplex and reports Positive/Negative (sometimes with an index or Equivocal). Positive indicates past exposure and immune memory but doesn’t prove active disease, locate the site of infection, or date the exposure. Negative suggests no prior exposure, but early infection can be missed; antibodies typically develop 2–12 weeks after exposure (occasionally up to 16 weeks for HSV-2), so retest if recent exposure is likely or symptoms are new. Be cautious with low-positive index values, which may warrant confirmatory testing. IgM is not recommended due to poor specificity. Discuss antiviral options (episodic or suppressive) and risk-reduction if relevant, and interpret using your lab’s specific cutoffs.

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Infectious Disease Profile

Optimal range:   0 - 0.91 / index

HSV-2 Ab, IgG refers to the antibody test for herpes simplex virus type 2 (HSV-2) using the immunoglobulin G (IgG) class of antibodies. This test is employed to detect the presence of IgG antibodies specifically related to the HSV-2 virus in the bloodstream. The presence of these antibodies typically indicates a prior exposure to the herpes simplex virus type 2, suggesting a past infection.

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Sensory Motor Neuropathy Complete Antibody Panel, Quest Diagnostics

Reference range:   POSITIVE, NEGATIVE

Neuronal nuclear (Hu) antibody is present in patients with various neurological symptoms including two paraneoplastic syndromes: sensory neuropathy (PSN) and encephalomyelitis (PEM). The presence of Hu antibody strongly suggests underlying small cell lung carcinoma (SCLC). Hu antibody is identified by IFA and confirmed by Western Blot. A negative result does not exclude the possibility of a SCLC or other malignant tumor.

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HU Antibody Screen w/Refl to Titer and WB, Quest Diagnostics

Reference range:   Negative, Positive, Fluorescence noted

The Hu Ab Screen, IFA (Immunofluorescence Assay), Serum test is a pivotal diagnostic tool in neurology and oncology, primarily utilized for the detection of paraneoplastic neurological syndromes associated with cancers like small cell lung cancer. This test identifies Hu antibodies, markers of an autoimmune response where the immune system targets the nervous system, often in response to an underlying malignancy. The application of IFA, known for its sensitivity and specificity, ensures accurate detection of these antibodies. A positive result can be a critical early indicator of cancer, even before it is clinically evident, and aids in diagnosing associated neurological conditions such as encephalomyelitis and sensory neuronopathy.

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Array 12 – Pathogen-Associated Immune Reactivity Screen, Cyrex Laboratories

Optimal range:   1 - 2.6 ELISA Index

Heat shock protein 60 (HSP60) is a mitochondrial chaperonin that plays a role in the transportation and refolding of proteins from the cytoplasm into the mitochondrial matrix.

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Endocrinology

Reference range:   Positive, Negative

A qualitative HCG blood test checks if there is a hormone called human chorionic gonadotropin in your blood. HCG is a hormone produced in the body during pregnancy.

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Herpes Testing

Reference range:   Negative, Positive

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Herpes Testing

Optimal range:   0 - 0.1 Units

Human Herpesvirus 6 (HHV-6) is a common virus that primarily infects children, causing a mild illness known as roseola, characterized by high fever and a distinctive rash. The presence of IgM antibodies against HHV-6 in the blood is a significant marker used to diagnose recent or active infection. IgM, which stands for immunoglobulin M, is the first type of antibody the immune system produces in response to an infection. When HHV-6 IgM is detected, it indicates that the body is currently fighting the virus, suggesting either a primary infection or a reactivation of the virus in individuals who were previously infected. Since HHV-6 can lie dormant and reactivate later, especially in individuals with weakened immune systems, monitoring IgM levels can be crucial in clinical settings, particularly for patients undergoing immunosuppressive treatments or organ transplants. By understanding the role of HHV-6 IgM, healthcare providers can better assess and manage the implications of HHV-6 infections, contributing to improved patient care and outcomes.

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Array 12 – Pathogen-Associated Immune Reactivity Screen, Cyrex Laboratories

Optimal range:   0.2 - 1.4 ELISA Index

Human Herpesvirus-6 (HHV-6), belonging to the beta-herpesvirus subfamily, is a lymphotropic virus, which infects mainly T cells in vitro, causes acute and latent infections.

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Immune System

Optimal range:   344 - 2382 pg/mL

Transforming Growth Factor Beta 1 (TGF-β1) is a vital protein in human health, belonging to the broader TGF-β superfamily. This protein is a key regulator in numerous bodily functions, primarily focusing on cell growth, division, and development. Its role is crucial in maintaining the health and stability of tissues and organs. TGF-β1 is particularly significant in the body's healing processes. During wound repair and tissue regeneration, TGF-β1 acts as a critical coordinator, guiding cells in the repair and healing process. This function makes it an essential component in medical and health research, particularly in understanding wound healing mechanisms.

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ZRT Laboratory (Urinary Neurotransmitters), ZRT Laboratory

Optimal range:   3737 - 7048 µg/g creatinine

Homovanillate (aka Homovanillic Acid) is a dopamine metabolite.

Homovanillate and Vanilmandelate are breakdown products from neurotransmitters involved in hormone and nerve impulse transmission, called catecholamines.

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Organic Acids Test (OAT) - Nutritional and Metabolic Profile, Mosaic Diagnostics

Optimal range:   0.16 - 1.8 Ratio

The Organic Acids Test measures levels of HVA (homovanillic acid) and VMA (vanillylmandelic acid), the metabolites of the neurotransmitters, dopamine and epinephrine/norepinephrine. It also measures the ratio of the two metabolites.

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Organic Acids Test (OAT) - Nutritional and Metabolic Profile, Mosaic Diagnostics

Optimal range:   0.32 - 1.4 Ratio

The Organic Acids Test measures levels of HVA (homovanillic acid) and VMA (vanillylmandelic acid), the metabolites of the neurotransmitters, dopamine and epinephrine/norepinephrine. It also measures the ratio of the two metabolites.

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Organic Acids Test (OAT) - Nutritional and Metabolic Profile, Mosaic Diagnostics

Optimal range:   0.23 - 2.8 mmol/mol creatinine

The Organic Acids Test measures levels of HVA (homovanillic acid) and VMA (vanillylmandelic acid), the metabolites of the neurotransmitters, dopamine and epinephrine/norepinephrine. It also measures the ratio of the two metabolites.

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Organic Acids Test (OAT) - Nutritional and Metabolic Profile, Mosaic Diagnostics

Optimal range:   0.1 - 1.8 Ratio

HVA and DOPAC are the major metabolites of dopamine. HVA stands for Homovanillic acid and DOPAC stands for Dihydroxyphenylacetic.

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Organic Acids Test (OAT) - Nutritional and Metabolic Profile, Mosaic Diagnostics

Optimal range:   0.17 - 1.6 mmol/mol creatinine

HVA and DOPAC are the major metabolites of dopamine. HVA stands for Homovanillic acid and DOPAC stands for Dihydroxyphenylacetic.

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