Glutamate functions as the major excitatory neurotransmitter and metabolic fuel throughout the body. Glutamate is produced in your body, and is also found in many foods.

Glutamate functions as the major excitatory neurotransmitter and metabolic fuel throughout the body. Glutamate is produced in your body, and is also found in many foods.

The brain's major excitatory neurotransmitter glutamate (also known as glutamic acid) functions as the "on" switch in the brain. Glutamate regulates appetite, thinking (cognition), increases gut motility, optimizes learning, modulates memory, mood and perception of pain, improves libido, and decreases sleep. The brain is the major contributor of glutamate in the body.

Glutamate is an excitatory neurotransmitter and is considered to be the most abundant neurotransmitter in the nervous system. Glutamate is involved in most aspects of normal brain function including cognition, memory and learning, although high levels of glutamate can cause excitotoxicity, a process where nerve cells are damaged by excessive stimulation.

Glutamate is an important marker included on the Amino Acids; Urine 24-hour panel provided by Doctor's Data. This amino acid plays a crucial role in the body, primarily as a neurotransmitter in the brain, where it helps in sending signals between nerve cells. It's one of the most abundant neurotransmitters and is essential for learning and memory. When measured in a urine test, the levels of glutamate can give valuable insights into a person's metabolic processes. Abnormal levels of glutamate in the urine can indicate various health issues. For example, elevated glutamate can suggest problems with neurological functions or an imbalance in amino acid metabolism. On the other hand, low levels might point to issues like inadequate protein intake or specific metabolic disorders. The 24-hour urine collection method used in this test helps to provide a comprehensive view of the glutamate levels over a full day, giving a more accurate assessment than a single snapshot might. This detailed information can be crucial for doctors to diagnose potential health issues and to recommend appropriate dietary adjustments or treatments to balance glutamate levels in the body.

The Glutamic Acid/Glutamine Ratio is used to identify specimen handling issues that cause spontaneous degradation of glutamine to glutamate, and can reveal the origin of difficulty maintaining systemic pH balance.

Glutamic acid is a nonessential amino acid is derived from the diet and from the breakdown of gut proteins. Glutamate is a major excitatory neurotransmitter in the brain. It plays a role in neuronal differentiation, migration, and survival in the developing brain. It is also involved in synaptic maintenance, neuroplasticity, learning, and memory.

Glutamic acid is a nonessential amino acid is derived from the diet and from the breakdown of gut proteins. Glutamate is a major excitatory neurotransmitter in the brain.

It plays a role in neuronal differentiation, migration, and survival in the developing brain. It is also involved in synaptic maintenance, neuroplasticity, learning, and memory.

Glutamate is present in many foods including cheese, seafood, meat, and spinach.

In spite of intake, the total pool of glutamic acid in the blood is small, due to its rapid uptake and utilization by tissues including muscle and the liver (which uses it to form glucose and lactate).

Glutamic acid is a nonessential amino acid is derived from the diet and from the breakdown of gut proteins. Glutamate is a major excitatory neurotransmitter in the brain. It plays a role in neuronal differentiation, migration, and survival in the developing brain. It is also involved in synaptic maintenance, neuroplasticity, learning, and memory.

Glutamic acid is a nonessential amino acid is derived from the diet and from the breakdown of gut proteins. Glutamate is a major excitatory neurotransmitter in the brain. It plays a role in neuronal differentiation, migration, and survival in the developing brain. It is also involved in synaptic maintenance, neuroplasticity, learning, and memory.

Glutamic acid is a nonessential amino acid is derived from the diet and from the breakdown of gut proteins. Glutamate is a major excitatory neurotransmitter in the brain. It plays a role in neuronal differentiation, migration, and survival in the developing brain. It is also involved in synaptic maintenance, neuroplasticity, learning, and memory.

Glutamic acid is a nonessential amino acid is derived from the diet and from the breakdown of gut proteins. Glutamate is a major excitatory neurotransmitter in the brain. It plays a role in neuronal differentiation, migration, and survival in the developing brain. It is also involved in synaptic maintenance, neuroplasticity, learning, and memory.

Glutamic acid is a nonessential amino acid is derived from the diet and from the breakdown of gut proteins. Glutamate is a major excitatory neurotransmitter in the brain. It plays a role in neuronal differentiation, migration, and survival in the developing brain. It is also involved in synaptic maintenance, neuroplasticity, learning, and memory.

Glutamic acid (glutamate) is a key amino acid involved in energy metabolism, neurotransmission, and detoxification. It’s central to the glutamate–glutamine cycle, which regulates brain activity and ammonia balance. Elevated levels may indicate oxidative stress, excitatory imbalance, or liver dysfunction, while low levels can reflect poor protein intake, mitochondrial inefficiency, or increased antioxidant demand. Monitoring glutamic acid on the OMX panel provides insights into both neurological health and metabolic function.

Glutamic acid (or Glutamate) is a major mediator of excitatory signals in the brain and is involved in most aspects of normal brain function including cognition, memory and learning.

Glutamic acid (or Glutamate) is a major mediator of excitatory signals in the brain and is involved in most aspects of normal brain function including cognition, memory and learning.

Glutamic acid decarboxylase is an enzyme found in brain and pancreas that converts glutamic acid (glutamate) into GABA, an inhibitory neurotransmitter. The glutamic acid decarboxylase test is a test that looks for antibodies directed against the glutamic acid decarboxylase enzyme.

Function:

Glutamic Acid Decarboxylase (GAD), a neuronal protein, is an enzyme responsible for the conversion of the excitatory neurotransmitter glutamate to the inhibitory neurotransmitter g-aminobutyric acid (GABA). GAD is also expressed by pancreatic beta cells.

Antibodies Appear:

- Battan disease [6]

- Celiac disease [3]

- Cerebellar ataxia [4]

- Gluten sensitivity [3]

- Polyendocrine autoimmune syndrome [2]

- Stiff-person syndrome [2]

- Type 1 Diabetes [2, 4, 7]

Known Cross-Reactions:

- Casein; [1]

- Coxsackievirus; [5]

- Gliadin; [7]

- Rotavirus; [9]

- Cytomegalovirus; [10, 11]

- Rubella; [12]

- Buckwheat, Amaranth, Rice, Corn, Yeast, Potato, Quinoa, Oats [13]

This test is intended for the semiquantitative determination of glutamic acid decarboxylase (GAD) antibody in human serum; it is useful as an aid in the diagnosis of type 1 diabetes mellitus (autoimmune mediated diabetes).