The marker Fusobacterium species refers to a group of bacteria that are part of the normal flora in the human gut but can also act as pathogens under certain conditions. Fusobacterium species are anaerobic bacteria, meaning they thrive in environments with little to no oxygen, such as the deeper layers of the mucous membrane lining the gut. In a healthy individual, these bacteria coexist peacefully with other microorganisms and contribute to the gut's ecological balance. However, if the balance is disrupted, Fusobacterium can become opportunistic pathogens, leading to infections. The presence of these bacteria in elevated levels on a GI panel can indicate an infection or dysbiosis (an imbalance in the microbial community), which may be associated with various gastrointestinal disorders, including inflammatory bowel disease and colon cancer. Therefore, the detection of Fusobacterium species on a GI panel is crucial for diagnosing potential infections or imbalances, guiding effective treatment plans to restore gut health.

Autoimmune Association: Systemic sclerosis or inflammatory bowel disease.

Fusobacterium spp. present in the oral and gut flora is carcinogenic and is associated with the risk of pancreatic and colorectal cancers. Fusobacterium spp. is also implicated in a broad spectrum of human pathologies, including Crohn’s disease and ulcerative colitis (UC).

Fusobacterium is very rarely found among the usual gut bugs, but it appears to flourish in colon cancer cells.

Gamma-aminobutyric acid (GABA) is an amino acid that functions as an inhibitory neurotransmitter. It serves one-third of brain neurons and is involved in depression and mania.

Although there are some dietary supplement and food sources for GABA (cruciferous vegetables, spinach, tomatoes, beans, and rice), the primary source may be endogenous prodution. Nervous tissue, the gut microbiome, the liver, pancreas, and endothelial cells are important sources for production.

This test measures the amount of G6PD in red blood cells to help diagnose a G6PD deficiency.

G6PD deficiency is an inherited condition. It is when the body doesn’t have enough of an enzyme called G6PD (glucose-6-phosphate dehydrogenase).

This enzyme helps red blood cells work correctly. A lack of this enzyme can cause hemolytic anemia. This is when the red blood cells break down faster than they are made.

Glucose-6-phosphate dehydrogenase (G6PD) is an enzyme essential for energy production and found in all cells, including red blood cells (RBCs), where it safeguards them from toxic by-products of metabolism. A G6PD deficiency, a genetic disorder affecting over 400 million people worldwide, can lead to RBCs becoming susceptible to breaking apart (hemolysis), particularly when triggered by factors like stress, infections, drugs, or certain substances, like fava beans.

Gamma-aminobutyric acid (GABA) is an amino acid that functions as an inhibitory neurotransmitter. It serves one-third of brain neurons and is involved in depression and mania.

Although there are some dietary supplement and food sources for GABA (cruciferous vegetables, spinach, tomatoes, beans, and rice), the primary source may be endogenous prodution. Nervous tissue, the gut microbiome, the liver, pancreas, and endothelial cells are important sources for production.

Gamma-aminobutyric acid (GABA) is an amino acid that functions as an inhibitory neurotransmitter. It serves one-third of brain neurons and is involved in depression and mania.

Although there are some dietary supplement and food sources for GABA (cruciferous vegetables, spinach, tomatoes, beans, and rice), the primary source may be endogenous prodution. Nervous tissue, the gut microbiome, the liver, pancreas, and endothelial cells are important sources for production.

Gamma-aminobutyric acid (GABA) is an amino acid that functions as an inhibitory neurotransmitter. It serves one-third of brain neurons and is involved in depression and mania.

Although there are some dietary supplement and food sources for GABA (cruciferous vegetables, spinach, tomatoes, beans, and rice), the primary source may be endogenous prodution.

Nervous tissue, the gut microbiome, the liver, pancreas, and endothelial cells are important sources for production. Endogenous GABA is produced by the decarboxylation of the excitatory neurotransmitter glutamic acid. It can also be produced from the diamine putrescine using diamine oxidase (DAO).

Gamma-aminobutyric acid (GABA) is an amino acid that functions as an inhibitory neurotransmitter. It serves one-third of brain neurons and is involved in depression and mania.

Although there are some dietary supplement and food sources for GABA (cruciferous vegetables, spinach, tomatoes, beans, and rice), the primary source may be endogenous prodution. Nervous tissue, the gut microbiome, the liver, pancreas, and endothelial cells are important sources for production.

GABA is a neurotransmitter that inhibits nervous system activity, producing a relaxation effect.

Gamma-aminobutyric acid (GABA) is an amino acid that functions as an inhibitory neurotransmitter. It serves one-third of brain neurons and is involved in depression and mania.

Although there are some dietary supplement and food sources for GABA (cruciferous vegetables, spinach, tomatoes, beans, and rice), the primary source may be endogenous prodution. Nervous tissue, the gut microbiome, the liver, pancreas, and endothelial cells are important sources for production.

GABA is a neurotransmitter that inhibits nervous system activity, producing a relaxation effect.

Gamma-linolenic acid (GLA) is an omega-6 fatty acid. The body converts linoleic acid to gamma-linolenic acid and then to arachidonic acid (AA). 

You can get gamma-linolenic acid from several plant-based oils, including evening primrose oil (EPO), borage oil, and black currant seed oil. Most of these oils also contain some linoleic acid.

Gamma-linolenic acid contains 18 carbons and 3 double bonds. It is synthesized from linoleic acid by adding a double bond using the delta-6-desaturase enzyme. This enzymatic reaction is very slow and further impaired in vitamin and mineral deficiencies such as zinc and cobalt. Stress, smoking, alcohol, and systemic inflammatory conditions can also slow this conversion.

γ-linolenic acid (GLA) is an omega-6 fatty acid containing 18 carbons and 3 double bonds (18:3n6).

It is synthesized from LA by adding a double bond using the delta-6-desaturase enzyme. This enzymatic reaction is very slow and further impaired in vitamin and mineral deficiencies such as zinc and cobalt.

Stress, smoking, alcohol, and systemic inflammatory conditions can also slow this conversion.

This test measures the amount of G6PD in red blood cells to help diagnose a G6PD deficiency.

G6PD deficiency is an inherited condition. It is when the body doesn’t have enough of an enzyme called G6PD (glucose-6-phosphate dehydrogenase).

This enzyme helps red blood cells work correctly. A lack of this enzyme can cause hemolytic anemia. This is when the red blood cells break down faster than they are made.

γ-amino butyric acid (GABA) is the major inhibitory neurotransmitter of the brain. Its major precursor is L-glutamate, which is converted to GABA via the enzyme glutamate decarboxylase (GAD).

GABA has also been detected in other peripheral tissues including intestines, stomach, Fallopian tubes, uterus, ovaries, testes, kidneys, urinary bladder, the lungs and liver, albeit at much lower levels than in neurons or insulin- producing β-cells.

GABA's principial role:

GABA's principal role is reducing neuronal excitability throughout the nervous system. In humans, GABA is also directly responsible for the regulation of muscle tone. In addition, GABA controls the mood, sleep, blood pressure while preventing anxiety.

GABA is sold as a dietary supplement. GABA is found ubiquitously among plants. GABA is prevalent in foods such as Adzuki bean, barley, broccoli, buckwheat, chestnut, common bean, kale, lupin, maypop, mouse-ear hawkweed, oat, pea, pokeroot, potato, rice, shiitake, soya bean, spinach, St John’s wort, sweet potato, tea, tomato, valerian, wheat, wild celery.

GABA stands for Gamma-aminobutyric acid (γ-Aminobutyric Acid) and is a nonessential protein amino acid. GABA is an inhibitory neurotransmitter in the central nervous system.

This is GABA measured in urine on Sanesco Health's HPA profile, reported as a ratio to creatinine — ug/g Cr means micrograms per gram of creatinine. There is no blood GABA number on this report.

The stored range, 600 to 1100 ug/g Cr, is Sanesco's optimal band. The laboratory also prints a reference range of 150 to 700, and the two overlap only between 600 and 700. Sanesco's report states that its low and high marks are based on the optimal intervals, so a result of 400 is inside the reference range and marked low in both places — platform and paper report agree.

Optimal bands here are laboratory-specific: ZRT's is 193 to 367 µg/g creatinine for the same analyte and units, and ZRT flags against its reference interval instead. A number read against any range but its own report's will be misread.

On meaning, the honest answer is narrow. This measures GABA leaving the body in urine, and is not established as a measure of brain GABA: the primary review calls the CNS-to-urine association "not yet defined". The vendor bibliography cited here does not mention GABA, and the one randomized trial to measure urinary GABA was a seventeen-person subset in an industry-funded study. Read it with the clinician who ordered it.

GABA stands for Gamma-aminobutyric acid (γ-Aminobutyric Acid) and is a nonessential protein amino acid. GABA is an inhibitory neurotransmitter in the central nervous system.