If you can test it, we can track it — all test results, including the ones from your favorite labs.

Optimal Result: 1515 - 2710 µg/g creatinine.

Glutamate functions as the major excitatory neurotransmitter and metabolic fuel throughout the body. Glutamate is produced in your body, and is also found in many foods.

Functions of Glutamate:

Glutamate is a neurotransmitter that sends signals in the brain and throughout the nerves in the body.
Glutamate plays an important role during brain development. Normal levels of glutamate also help with learning and memory.

Glutamate in food:

Glutamate is probably best known as “monosodium glutamate” or “MSG” which is used as a flavor or taste enhancer in food. It is usually available together with other food additives and spices in most large food stores. Some people may also have heard the term “Chinese restaurant syndrome” which is a sudden fall in blood pressure with subsequent fainting after ingestion of very spicy food.

References:

- Marko AM, Gerrard JW, Buchan DJ. Glutamic acid derivatives in adult celiac disease. II. Urinary total glutamic acid excretion. Can Med Assoc J 1960;83:1324-5. (https://www.ncbi.nlm.nih.gov/pubmed/13766911)

- Belanger R, Chandramohan N, Misbin R, Rivlin RS. Tyrosine and glutamic acid in plasma and urine of patients with altered thyroid function. Metabolism 1972;21:855-65. (https://www.ncbi.nlm.nih.gov/pubmed/5057275)

- Ragginer C, Lechner A, Bernecker C, et al. Reduced urinary glutamate levels are associated with the frequency of migraine attacks in females. Eur J Neurol 2012;19:1146-50. (https://www.ncbi.nlm.nih.gov/pubmed/22435925)

- https://www.ncbi.nlm.nih.gov/books/NBK62187/

- https://academic.oup.com/jn/article/130/4/1007S/4686662

What does it mean if your Glutamate result is too low?

Glutamate is low in patients with migraines. Clinically, low glutamate is implicated in depression, chronic fatigue, lack of concentration, low energy levels, and sleep disturbances.

What does it mean if your Glutamate result is too high?

Glutamate is high in celiac disease and hyperthyroidism. Clinically, high glutamate is suspected in anxiety, autism spectrum disorder, depression and sleep issues.

If you can test it, we can track it — all test results, including the ones from your favorite labs.

10 000+ happy clients
100% satisfaction
★★★★★ customer support

Essential Plan


  • Monthly subscription
  • Instant interpretation
  • Use the free self-upload form
  • Additional charge for upload service
  • 1500+ biomarkers explained
  • Recommendations
  • Cancel anytime

Advanced Plan


  • Yearly subscription
  • Instant interpretation
  • We upload five reports for you
  • Use the free self-upload form
  • 1500+ biomarkers explained
  • Nutrition Recommendations
  • Online support
  • Cancel anytime

Own It For Life premium plan


  • No subscription
  • Unlimited access
  • Unlimited storage
  • Instant interpretations
  • We upload ten reports for you
  • Use the free self-upload form
  • 1500+ biomarkers explained
  • Nutrition Recommendations
  • Dedicated support

We implement proven measures to keep your data safe.

At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.

General Data Protection Regulation (GDPR). HIPAA compliance for healthcare professionals