MCHC significa concentração de hemoglobina corpuscular média. O MCHC faz parte dos índices dos glóbulos vermelhos, juntamente com o MCH e o MCV. Esses parâmetros refletem o tamanho e o conteúdo de hemoglobina das hemácias. Tradicionalmente, eles são utilizados para auxiliar no diagnóstico diferencial de anemias.

Stool normally contains about 75% water and ideally should be formed and soft. Stool consistency can vary based upon transit time and water absorption.

Outros nomes: Plaquetas, Contagem de Trombócitos

O que são as plaquetas?
As plaquetas (também conhecidas como trombócitos) são pequenos fragmentos celulares incolores presentes no sangue que formam coágulos e ajudam a interromper ou prevenir sangramentos.

Onde as plaquetas são produzidas?
As plaquetas são produzidas na medula óssea, o tecido esponjoso dentro dos ossos. A medula óssea contém células-tronco que se desenvolvem em glóbulos vermelhos, glóbulos brancos e plaquetas.

Qual é a principal função das plaquetas?
As plaquetas formam coágulos quando há danos a um vaso sanguíneo. Por exemplo, se você cortar o dedo, as plaquetas se misturam com os fatores de coagulação (proteínas presentes no sangue). Juntas, elas formam uma espécie de "cola" que interrompe o sangramento.

The copeptin test is a helpful tool used by doctors to check on a specific part of our body's hormone system. Copeptin is a piece of a larger hormone called pre-provasopressin, which breaks down into three parts, including vasopressin. Vasopressin is important because it helps control how much water our bodies keep and how much we pee out. It's hard to measure vasopressin directly because it doesn't last long in our blood and is present in tiny amounts. That's where copeptin comes in – it's easier to measure and tells us how much vasopressin our body is making.

Like most trace minerals, copper acts as an enzyme cofactor in several key metabolic processes in the body. Among its many functions, copper aids in the formation of bone, hemoglobin and red blood cells, therefore enabling the efficient transport of oxygen throughout the body. In addition, copper works in balance with vitamin C and zinc to manufacture elastin (skin protein) as well as collagen and other structural proteins in cartilage and tendons. It is also involved in the healing process, energy production, hair and skin coloring (production of melanin) and taste sensitivity. Copper stimulates the absorption of iron through the copper transport protein ceruloplasmin. Copper also aids in the metabolism of several fatty acids and helps prevent oxidative damage by serving as a cofactor to superoxide dismutase. In addition, copper is needed for proper insulation (mylination) of nerve cells and serves as a cofactor for the synthesis of the neurotransmitter norepinephrine.

Fecal copper (Cu) provides an estimate of very recent exposure to Cu, and to some extent biliary Cu excretion. The biliary / fecal route is the main route of excretion for Cu from the body.

Copper, a trace element, is a crucial component on a Toxic and Essential Elements panel when assessed in whole blood. It plays a vital role in numerous physiological processes, acting as a key cofactor in various enzymatic reactions. Copper is integral in the formation of red blood cells, the maintenance of healthy nerves and bones, and the absorption and utilization of iron. It also contributes to the synthesis of ATP, the body's primary energy currency, and is involved in the formation of connective tissue and the functioning of the immune system.

Copper is part of enzymes, which are proteins that help biochemical reactions occur in every cell. Copper is involved in the absorption, storage and metabolism of iron.

Sources:

Legumes, mushrooms, chocolate, nuts and seeds, shellfish and liver are high in copper all greater than 2.4 µg per gram.

Food, water and air (via combustion and fossil fuels and agriculture) are sources of copper.

Copper pipes and fixtures in household plumbing may allow copper to leak into water.

Sources:

Legumes, mushrooms, chocolate, nuts and seeds, shellfish and liver are high in copper all greater than 2.4 µg per gram.

Food, water and air (via combustion and fossil fuels and agriculture) are sources of copper.

Copper pipes and fixtures in household plumbing may allow copper to leak into water.

Copper is an essential trace element involved in antioxidant defense, immune response, nerve cell development, and iron metabolism. It also serves as a cofactor for numerous vital enzymes and proteins. The human body contains approximately 100 mg of copper, with the highest concentrations found in the brain and liver.

Copper is primarily absorbed in the stomach and small intestine, where higher pH levels help release it from dietary macromolecules. Once absorbed, copper is transported in the blood by albumin and transcuperin to the liver, where it binds to ceruloplasmin, a copper-carrying protein. Ceruloplasmin production is stimulated by adrenal hormones, so dysfunction in the liver or adrenal glands can disrupt copper balance, potentially leading to copper buildup in tissues. Under normal conditions, the body maintains copper homeostasis through biliary excretion, preventing toxicity.

Hair Copper (Cu) levels are usually indicative of body status, except that exogenous contamination may occur giving a false normal (or false high). Common sources of contamination include: permanent solutions, dyes, bleaches, and swimming pools/hot tubs in which Cu compounds have been used as algaecides.

Cu is an essential element that activates specific enzymes. Erythrocyte superoxide dismutase (SOD) is a Cu (and zinc) dependent enzyme; lysyl oxidase which catalyzes crosslinking of collagen is another Cu dependent enzyme. Adrenal catecholamine synthesis is Cu dependent, because the enzyme dopamine beta-hydroxylase, which catalyzes formation of norepinephrine from dopamine, requires Cu.

If hair Cu is in the normal range, this usually means tissue levels are in the normal range. However, under circumstances of contamination, a real Cu deficit could appear as a (false) normal. If symptoms of Cu deficiency are present, a whole blood or red blood cell elements analysis can be performed for confirmation of Cu status.

Copper serum is one of the diagnostic methods of ascertaining whether a patient is suffering from some kind of liver problem or from a genetic disease called Wilson’s disease.