Streptococcus is a member of Gram-positive lactic acid-producing bacteria (LAB) that belonged to Firmicutes phylum. Many strains of Streptococcus are non-pathogenic and occur as commensal flora on the skin, the oral cavity, nasopharynx, upper respiratory tract, urogenital, and gastrointestinal tracts. Some species of Streptococcus are responsible for numerous human inflammatory diseases including pharyngitis, meningitis, endocarditis, necrotyzing fasciitis, and those that are immune mediated, such as acute glumeronephritis, acute rheumatic fever, and colon cancer. Interaction of some virulence factors of Streptococci with immune cells could elicit inflammatory response in different organs. Association of Streptococcusbovis with IBD and colon cancer was reported in previous studies. In one study, it was shown that Streptococci are the predominant group of bacteria in inflamed colonic mucosa of CD patients; however this association was not verified in patients with UC. Contrary to these results reduction of Streptococci in IBD patients were observed in studies that investigated health-beneficial effects of these bacteria.
------------------------------------------------------------------------------------
References:
- Relative Abundance of Streptococcus spp. and its Association with Disease Activity in Inflammatory Bowel Disease Patients Compared with Controls [L]
- Herrera P, Kwon YM, Ricke SC. Ecology and pathogenicity of gastrointestinal Streptococcus bovis. Anaerobe. 2009; 15(1-2) : 44 -54 [DOI] [PubMed]
- Rooks MG, Veiga P, Wardwell-Scott LH, Tickle T, Segata N, Michaud M, et al. Gut microbiome composition and function in experimental colitis during active disease and treatment-induced remission. ISME J. 2014; 8(7) : 1403 -17 [DOI] [PubMed]
- Henneke P, Morath S, Uematsu S, Weichert S, Pfitzenmaier M, Takeuchi O, et al. Role of lipoteichoic acid in the phagocyte response to group B streptococcus. J Immunol. 2005; 174(10) : 6449 -55 [DOI] [PubMed]
- Dinis M, Plainvert C, Kovarik P, Longo M, Fouet A, Poyart C. The innate immune response elicited by Group A Streptococcus is highly variable among clinical isolates and correlates with the emm type. PLoS One. 2014; 9(7) [DOI] [PubMed]
- Al-Jashamy K, Murad A, Zeehaida M, Rohaini M, Hasnan J. Prevalence of colorectal cancer associated with Streptococcus bovis among inflammatory bowel and chronic gastrointestinal tract disease patients. Asian Pac J Cancer Prev. 2010; 11(6) : 1765 -8 [PubMed]
- Fyderek K, Strus M, Kowalska-Duplaga K, Gosiewski T, Wedrychowicz A, Jedynak-Wasowicz U, et al. Mucosal bacterial microflora and mucus layer thickness in adolescents with inflammatory bowel disease. World J Gastroenterol. 2009; 15(42) : 5287 -94 [DOI] [PubMed]
- Boer, C.G., Radjabzadeh, D., Medina-Gomez, C. et al. Intestinal microbiome composition and its relation to joint pain and inflammation. Nat Commun 10, 4881 (2019). [L]
Understand and improve your laboratory results with our health dashboard.
Upload your lab reports and get interpretation today.
Our technology helps to understand, combine, track, organize, and act on your medical lab test results.
Many adults carry Streptococcus in their bodies, usually in the bowel, vagina, rectum, bladder or throat, and have no signs or symptoms.
In some cases, however, group Streptococcus can cause a urinary tract infection or more-serious infections such as blood infections (bacteremia) or pneumonia.
Signs and symptoms might include:
- Fever
- Sluggishness and a lack of energy (lethargy)
- Difficulty breathing
- Irritability
- Jaundice
If you have signs or symptoms of a Streptococcus infection — particularly if you're pregnant, you have a chronic medical condition or you're older than 65 — contact your doctor right away.
-----------
A recent study [L] has shown that there was a relative increase in abundance of Streptococcus spp. among IBD (=Inflammatory bowel disease) patients compared with the control group. Inflammatory bowel disease (IBD) includes various forms of disorders; however crohn’s disease (CD) and ulcerative colitis (UC) are 2 major types of this disease.
Another study has shown that abundance of Streptococcus species is associated with increased knee pain [L]
Interpret Your Lab Results
Upload your lab report and we’ll interpret and provide you with recomendations today.
Get StartedGet Started With Our Personal Plan
Advanced Plan
Unlimited Plan
Are You a Health Professional?
Get started with our professional plan
Welcome to Healthmatters Pro.
Save time on interpreting lab results with the largest database of biomarkers online. In-depth research on any test at your fingertips, all stored and tracked in one place. Learn more
Pro Plan
for health professionals
$45 per month
At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.
AA/EPA, Akkermansia muciniphila, Alloprevotella, Alpha Gliadin IgG, Alpha-Beta Gliadin IgG, Amylase/Protease Inhibitors IgG, Anti-Actin IgG, Anti-LPS (IgG + IgM), Anti-LPS IgA, Anti-Zonulin IgG, Arachidonic acid (AA), Bacillus coagulans, Bacteroides, Bifidobacterium bifidum, Bifidobacterium infantis, Bifidobacterium lactis, Clostridium, Clotridiales Incertae Sedis IV, Copper to Zinc Ratio, Eggerthella lenta, Escherichia coli Nissle, Faecalibacterium, Farinins IgG, Gamma Gliadin IgG, Globulins IgG, Gluteomorphin IgG, HMW Glutenin IgG, Lactobacillus animalis, Lactobacillus paracasei, Linoleic acid (LA), LMW Glutenin IgG, Omega Gliadin IgG, Oscillospira, Porphyromonas gingivalis, Prodynorphin IgG, Pseudobutyrivibrio, Purinin IgG, Serpin IgG, Streptococcus, Total Omega-6, Tyzzerella