HMW (high molecular weight) glutenin is a protein component found in wheat gluten. Gluten is a mixture of proteins found in wheat, barley, and rye that provides the elasticity and texture in dough and other baked goods.
The gluten proteins can be divided into two main groups: the gliadins and the glutenins. The glutenins can be further divided into the low molecular weight (LMW) glutenins and the high molecular weight (HMW) glutenins.
The HMW glutenins are larger and more complex proteins than the LMW glutenins, and they play an important role in determining the quality and elasticity of wheat dough. The HMW glutenins are involved in the formation of strong and stable gluten networks, which are essential for producing high-quality bread and other baked goods.
Scientists have found that the genetic makeup of the HMW glutenin proteins can affect the baking quality and nutritional properties of wheat. This has led to efforts to develop wheat varieties with specific HMW glutenin genes that produce better-quality bread or have improved nutritional properties.
In individuals with celiac disease or gluten sensitivity, the immune system reacts to certain gluten proteins, including HMW glutenin, leading to inflammation and damage to the small intestine. This can cause a range of symptoms and long-term health problems.
The presence of antibodies to HMW glutenin in the blood can be used as a diagnostic tool for celiac disease, along with other markers such as antibodies to gliadin and tissue transglutaminase. Testing for these antibodies can help healthcare professionals confirm a diagnosis of celiac disease or gluten sensitivity and guide appropriate treatment and management.
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Antibodies to HMW (high molecular weight) glutenin are immunoglobulins produced by the immune system in response to the presence of HMW glutenin proteins in the body. These antibodies are part of the immune system's defense mechanism against foreign substances, including harmful pathogens and substances that the body recognizes as allergens or antigens.
In the context of celiac disease and non-celiac gluten sensitivity, individuals with these conditions produce antibodies to certain gluten proteins, including HMW glutenin. These antibodies recognize and bind to the HMW glutenin proteins, triggering an immune response that can cause inflammation and damage to the lining of the small intestine.
It is important to note that the production of antibodies to HMW glutenin alone is not sufficient to diagnose celiac disease or gluten sensitivity. Additional testing, such as a small intestinal biopsy, may be necessary to confirm the diagnosis.
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Anthony
Unlimited Plan Member since 2021
I have been using Healthmatters.io since 2021. I travel all over the world and use different doctors and health facilities. This site has allowed me to consolidate all my various test results over 14 years in one place. And every doctor that I show this to has been impressed. Because with any health professional I talk to, I can pull up historical results in seconds. It is invaluable. Even going back to the same doctor, they usually do not have the historical results from their facility in a graph format. That has been very helpful.
Karin
Advanced Plan Member since 2020
What fantastic service and great, easy-to-follow layouts! I love your website; it makes it so helpful to see patterns in my health data. It's truly a pleasure to use. I only wish the NHS was as organized and quick as Healthmatters.io. You've set a new standard for health tracking!
Paul
Healthmatters Pro Member since 2024
As a PRO member and medical practitioner, Healthmatters.io has been an invaluable tool for tracking my clients' data. The layout is intuitive, making it easy to monitor trends and spot patterns over time. The ability to customize reports and charts helps me present information clearly to my clients, improving communication and outcomes. It's streamlined my workflow, saving me time and providing insights at a glance. Highly recommended for any practitioner looking for a comprehensive and user-friendly solution to track patient labs!
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AA/EPA, Akkermansia muciniphila, Alloprevotella, Alpha Gliadin IgG, Alpha-Beta Gliadin IgG, Amylase/Protease Inhibitors IgG, Anti-Actin IgG, Anti-LPS (IgG + IgM), Anti-LPS IgA, Anti-Zonulin IgG, Arachidonic acid (AA), Bacillus coagulans, Bacteroides, Bifidobacterium bifidum, Bifidobacterium infantis, Bifidobacterium lactis, Clostridium, Clotridiales Incertae Sedis IV, Copper to Zinc Ratio, Eggerthella lenta, Escherichia coli Nissle, Faecalibacterium, Farinins IgG, Gamma Gliadin IgG, Globulins IgG, Gluteomorphin IgG, HMW Glutenin IgG, Lactobacillus paracasei, Linoleic acid (LA), LMW Glutenin IgG, Omega Gliadin IgG, Oscillospira, Porphyromonas gingivalis, Prodynorphin IgG, Pseudobutyrivibrio, Purinin IgG, Serpin IgG, Streptococcus, Total Omega-6, Tyzzerella
