Gluteomorphin, also known as gliadorphin, is a peptide that is derived from the digestion of gluten in the gastrointestinal tract. Specifically, gluteomorphin is produced when the digestive enzymes break down a protein in gluten called gliadin.
Gluteomorphin has been found to have opioid-like effects, meaning that it can bind to the opioid receptors in the brain and produce feelings of euphoria and relaxation. Some researchers have suggested that this may be one reason why people with gluten sensitivity or celiac disease may experience cravings or addiction-like behaviors when consuming gluten-containing foods.
However, the effects of gluteomorphin are not well understood and further research is needed to determine its exact role in gluten-related disorders. It is important to note that gluteomorphin is not a cause of celiac disease or gluten sensitivity, but rather a byproduct of gluten digestion.
If you suspect you have gluten sensitivity or celiac disease, it is important to speak with a healthcare professional who can provide you with accurate information and testing options.
Antibodies to gluteomorphin have been found to be elevated in individuals with gluten sensitivity associated neurochemical disorders.
If a person has elevated antibodies to Gluteomorphin or Prodynorphin, they may have severe neurochemical reactions to gluten and also create what is called a gluteomorphin withdrawal response. This is a response that causes a patient to have significant reactions such as depression, mood swings, abnormal bowel activity when they go on a gluten-free diet. If this occurs the person must hang in there for a couple of weeks being gluten-free to potentially avoid harmful disorders.
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