A healthy result should fall into the range 0 - 38 U/L, or 0.00 - 38.00 IU/L.

Gamma-glutamyl transpeptidase (GGT) is an enzyme found in many body tissues, the most notable being the liver. A GGT test may be used to determine the cause of elevated alkaline phosphatase (ALP). GGT and ALP are both elevated in disease of the bile ducts and in some liver diseases, but only ALP will be elevated in bone disease. Comparing the two test results can help determine if liver or bone disease is the cause of abnormal enzyme levels. For this reason, a GGT test is often run alongside other tests when a liver issue is suspected, such as: ALP, ALT, AST, and bilirubin tests, to differentiate between liver disease, bile duct disorders, and bone disease. Some signs and symptoms of liver damage include:

            -Weakness, fatigue

            -Loss of appetite

            -Nausea and vomiting

            -Abdominal swelling / pain

            -Jaundice (yellowing of the skin / eyes)

            -Dark urine, light-colored stool

            -Itching

Alcohol abuse is also known to affect GGT levels; therefore, GGT tests are sometimes ordered to monitor alcohol-dependency treatments and compliance with treatment programs in those with a history of alcohol abuse.

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