Alpha-2-Globulin, Serum

Optimal Result: 0.4 - 1 g/dL.

Protein in the serum is made up of albumin (∼ 60%) and globulin.

Globulins are divided into alpha-1, alpha-2, beta, and gamma globulins.

Globulins are made in your liver by your immune system. They play an important role in liver function, blood clotting, and fighting infection. In general, alpha and gamma globulin protein levels increase when there is inflammation in the body.

What does it mean if your Alpha-2-Globulin, Serum result is too low?

Decreased alpha-2 globulin proteins may indicate:

Breakdown of red blood cells

What does it mean if your Alpha-2-Globulin, Serum result is too high?

Elevated Alpha-2-Globulin results in a protein electrophoresis indicate a potential inflammatory condition in the body. Protein electrophoresis is a lab test that measures the types of proteins in the serum (fluid part of blood). 

An increase in Alpha-2-Globulin proteins can be associated with both acute and chronic inflammatory conditions. It is important to note that this information is based on general trends, and the specific interpretation of the results should be done in conjunction with other clinical findings and medical history by a healthcare provider.

Possible reasons for elevated Alpha-2-Globulin levels could include acute inflammatory diseases, chronic inflammatory diseases (such as rheumatoid arthritis or systemic lupus erythematosus), or other conditions associated with inflammation in the body.

It's important to discuss the results with a healthcare provider to determine the underlying cause of the elevated Alpha-2-Globulin levels and to decide on any further diagnostic or treatment steps. Each patient's case is unique, and additional tests or examinations may be necessary to reach a definitive diagnosis and appropriate management plan.

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