Protein in the serum is made up of albumin (∼60%) and globulin. Together with albumin, globulin forms the total protein level on a blood test lab report. It includes carrier proteins, enzymes, clotting factors, and, predominantly, antibodies.
Globulin is categorized into three main groups:
- alpha globulins
- beta globulins
- gamma globulins
While alpha globulins and beta globulins are primarily transport proteins, gamma globulins are mainly comprised of immunoglobulins (Igs), also known as antibodies.
The major carrier beta globulins are Transferrin and Sex hormone-binding globulin.
Beta globulin has a target range of 0.7 - 1.3 g/dL.
References:
Serum Albumin and Globulin, https://www.ncbi.nlm.nih.gov/books/NBK204/
Beta Globulin, Serum
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