Bisphenol A (BPA) is a xenoestrogen, exhibiting estrogen-mimicking, hormone-like properties that raise concern about its suitability in some consumer products and food containers. Bisphenol A (BPA) is an organic synthetic compound and it is a starting material for the synthesis of plastics, primarily certain polycarbonates and epoxy resins, as well as some polysulfones and certain niche materials. BPA is an endocrine-disrupting chemical that has been found to bind to both of the nuclear estrogen receptors. A recent exposure to plastic that released excessive amounts of BPA into a food or a beverage could be identified by high levels of urinary BPA.
BPA is an endocrine disrupting chemical (EDC) derived from plastics used for making bottles, wraps for foods, and linings for food cans. BPA is not retained in the body for a prolonged period of time and is rapidly excreted into urine.
- High levels indicate excessive exposure to this environmental endocrine disruptor, particularly dangerous to the unborn fetus and young children.
- High urinary levels of BPA indicate recent exposure to plastics that released excessive amounts of BPA into food or beverages consumed in the past 24-48 hr
BPA acts as an EDC by binding to a activating both membrane and nuclear estrogen receptors in a manner similar to estradiol. Thus by mimicking the actions of endogenous estrogens, high levels of BPA can contribute to symptoms of estrogen dominance. High BPA levels have been associated with increased risks for many different health issues, including diabetes, breast cancer, and prostate cancer. When BPA levels are elevated, identification of its source and reducing exposure is worth considering.
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