3a-Dihydroprogesterone (3a-DHP), also known as 3a-hydroxyprogesterone, is an endogenous neurosteroid. It is biosynthesized by 3a-hydroxysteroid dehydrogenase from progesterone. 3a-DHP has been found to act as a positive allosteric modulator of the GABAA receptor and is described as being as active as allopregnanolone in regard to this action. In accordance, it has anxiolytic effects (= decreasing anxiety) in animals. 3a-DHP has also been found to inhibit the secretion of follicle-stimulating hormone (FSH) from the rat pituitary gland, demonstrating possible antigonadotrophic properties.
3a- and 20a- dihydroprogesterone, have tumor-inhibitory properties in breast cancer
Understand and improve your laboratory results with our health dashboard.
Upload your lab reports and get your interpretation today.
Our technology helps to understand, combine, track, organize, and act on your medical lab test results.
3a-Dihydroprogesterone is a metabolite of progesterone, a hormone produced in the female body primarily by the ovaries and, to a lesser extent, by the adrenal glands. This metabolite is involved in various physiological processes, and its levels can have implications for postmenopausal women's health.
→ Breast Cancer Risk: Elevated levels of circulating progesterone, which includes 3α-Dihydroprogesterone, have been associated with an increased risk of postmenopausal breast cancer in some studies. Women with higher circulating progesterone levels had an elevated risk of postmenopausal breast cancer.
→ Hormonal Regulation: Progesterone and its metabolites, including 3α-Dihydroprogesterone, play important roles in hormonal regulation in women's bodies. These hormones are involved in the menstrual cycle, pregnancy, and other reproductive functions.
It's important to note that the significance of 3α-Dihydroprogesterone levels can vary based on an individual's overall health, medical history, and specific hormone profiles. Elevated levels may have different implications for different women. Therefore, interpreting hormone levels should be done in consultation with a healthcare provider who can consider the individual's unique circumstances.
Interpret Your Lab Results
Upload your lab report, and we'll interpret and provide you with recommendations today.
Get Started
Monthly plan
Annual plan
Own it for life
Our exclusive data entry service is a convenient way to get your results into your private dashboard. Simply attach an image or a file of your lab test results, and one of our qualified data entry team members will add the results for you. We support all sorts of files, whether PDFs, JPGs, or Excel. This service is excellent whether you have a lot of reports to upload or are too busy to do the data entry yourself.
We strive to make the data entry process easy for you. Whether by offering dozens of templates to choose from that pre-populate the most popular laboratory panels or by giving you instant feedback on the entered values. Our data entry forms are an easy, fast, and convenient way to enter the reports yourself. There is no limit on how many lab reports you can upload.
$15 /month
billed every month
Most popular
Data entry included
$79 /year
$6.60/month billed annually
Data entry included
$250 /once
own it for life
Are You a Health Professional?
Get started with our professional plan
Welcome to Healthmatters Pro.
Save time on interpreting lab results with the largest database of biomarkers online. In-depth research on any test at your fingertips, all stored and tracked in one place. Learn more
Pro Monthly Plus
for health professionals
$75 per month
At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.
16a-OH Estrone, 2-MeO E1/2-OH E1, 2-MeO Estradiol, 2-MeO Estrone, 2-OH (E1 + E2)/16-a- OH E1, 2-OH Estradiol, 2-OH Estrone, 20a- Dihydroprogesterone, 3a- Dihydroprogesterone, 3a-Dihydroprogesterone (Postmenopausal), 4-MeO E1/4-OH E1, 4-MeO E2/4-OH E2, 4-MeO Estradiol, 4-MeO Estrone, 4-OH Estradiol, 4-OH Estrone, 5a,3a-Androstanediol, 5a,3a-Androstanediol (Postmenopausal), 5a-DHT, 5a-DHT (Postmenopausal), Allopregnanediol, Allopregnanediol (Postmenopausal), Allopregnanolone, Allopregnanolone (Postmenopausal), Androstenedione, Androsterone, Androsterone (Postmenopausal), Bisphenol A, Bisphenol A (Postmenopausal), Corticosterone, Cortisol/Cortisone, Creatinine (1st morning), Creatinine (2nd morning), Creatinine (Evening), Creatinine (Night), Creatinine (pooled), Deoxycorticosterone, DHEA, E3/(E1+E2), Epi-Testosterone, Estradiol, Estriol, Estrone, Etiocholanolone, Free Cortisol (1st Morning), Free Cortisol (2nd Morning), Free Cortisol (Evening), Free Cortisol (Night), Free Cortisone (1st Morning), Free Cortisone (2nd Morning), Free Cortisone (Evening), Free Cortisone (Night), Melatonin (1st Morning), Melatonin (2nd Morning), Melatonin (Evening), Melatonin (Night), Pgdiol/E2, Pregnanediol, T/Epi-T, Testosterone, Tetrahydrocortisol, Tetrahydrocortisone, Total Cortisol, Total Cortisone
