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Optimal range: 0.15 - 1.7 mmol/mol creatinine
Methylcitric is an organic acids that reflects decreased activity of the biotin-dependent enzyme propionyl-CoA carboxylase.
Optimal range: 0 - 5.7 mmol/mol creatinine
LEARN MOREOptimal range: 0.15 - 2.96 mmol/mol
Methylcitric is an organic acids that reflects decreased activity of the biotin-dependent enzyme propionyl-CoA carboxylase.
Reference range: Negative, Positive
Reduced methylenetetrahydrofolate reductase (MTHFR) enzyme activity is a genetic risk factor for hyperhomocysteinemia, especially when present with low serum folate levels. Two common variants in the MTHFR gene result in reduced enzyme activity. The "thermolabile" variant C677T [NM 005957.3: c.665C>T (p.A222V)] and A1298C [c. 1286A>C (p.E429A)] occur frequently in the general population.
Optimal range: 0 - 1.9 mmol/mol creatinine
Methylmalonic acid (MMA) is a substance produced in very small amounts and is necessary for human metabolism and energy production.
Optimal range: 0 - 1.64 ug/mg creatinine
Methylmalonic acid (MMA) is a substance produced in very small amounts and is necessary for human metabolism and energy production. In one step of metabolism, vitamin B12 promotes the conversion of methylmalonyl CoA (a form of MMA) to succinyl Coenzyme A. If there is not enough B12 available, then the MMA concentration begins to rise, resulting in an increase of MMA in the blood and urine. The measurement of elevated amounts of methylmalonic acid in the blood or urine serves as a sensitive and early indicator of vitamin B12 deficiency.
Optimal range: 0 - 2.3 mcg/mg creatinine
Methylmalonic acid (MMA) is a substance produced in very small amounts and is necessary for human metabolism and energy production.
Optimal range: 0 - 2.5 ug/mg
The measurement of elevated amounts of methylmalonic acid in the blood or urine serves as a sensitive and early indicator of vitamin B12 deficiency.
Optimal range: 0 - 3.5 ug/mg
The measurement of elevated amounts of methylmalonic acid in the blood or urine serves as a sensitive and early indicator of vitamin B12 deficiency.
Optimal range: 0 - 2.3 mmol/mol creatinine
Methylmalonic acid (MMA) is a substance produced in very small amounts and is necessary for human metabolism and energy production.
Optimal range: 0 - 2 mmol/mol creatinine
Other names: Methylmalonic Acid or MMA
Methylmalonic acid (MMA) is a substance produced in very small amounts and is necessary for human metabolism and energy production. In one step of metabolism, vitamin B12 promotes the conversion of methylmalonyl CoA (a form of MMA) to succinyl Coenzyme A. If there is not enough B12 available, then the MMA concentration begins to rise, resulting in an increase of MMA in the blood and urine. The measurement of elevated amounts of methylmalonic acid in the blood or urine serves as a sensitive and early indicator of vitamin B12 deficiency.
Optimal range: 0 - 2.3 mmol/mol creatinine
Methylmalonic acid (MMA) is a substance produced in very small amounts and is necessary for human metabolism and energy production.
Optimal range: 0 - 5.2 mmol/mol creatinine
LEARN MOREOptimal range: 0 - 1.9 mmol/mol creatinine
Methylmalonic Acid (MMA) is formed from propionylCoA via methylmalonyl-CoA. Major dietary sources of propionyl-CoA include valine, isoleucine, methionine, threonine, and odd chain fatty acids. MethylmalonylCoA is converted to succinyl-CoA to feed the Citric Acid Cycle via the enzyme methylmalonyl-CoA mutase. This enzyme is very vitamin B2 dependent. In B12 deficiency, methylmalonyl-CoA is hydrolyzed to methylmalonic acid.
Optimal range: 0 - 1.9 mmol/mol creatinine
Methylmalonic acid (MMA) is a substance produced in very small amounts and is necessary for human metabolism and energy production.
Optimal range: 0 - 24.9 nmol/mg Creatinine
Methylmalonic Acid (MMA) is formed from propionylCoA via methylmalonyl-CoA. Major dietary sources of propionyl-CoA include valine, isoleucine, methionine, threonine, and odd chain fatty acids. MethylmalonylCoA is converted to succinyl-CoA to feed the Citric Acid Cycle via the enzyme methylmalonyl-CoA mutase. This enzyme is very vitamin B2 dependent. In B12 deficiency, methylmalonyl-CoA is hydrolyzed to methylmalonic acid.
Optimal range: 0 - 1.85 ug/mgCR
Methylmalonic Acid (MMA) is formed from propionylCoA via methylmalonyl-CoA. Major dietary sources of propionyl-CoA include valine, isoleucine, methionine, threonine, and odd chain fatty acids. MethylmalonylCoA is converted to succinyl-CoA to feed the Citric Acid Cycle via the enzyme methylmalonyl-CoA mutase. This enzyme is very vitamin B2 dependent. In B12 deficiency, methylmalonyl-CoA is hydrolyzed to methylmalonic acid.
Optimal range: 0 - 2.21 mmol/mol
Methylmalonic acid (MMA) is a substance produced in very small amounts and is necessary for human metabolism and energy production.
Optimal range: 0 - 378 nmol/L , 0 - 0.38 nmol/ML
Methylmalonic acid is a compound that reacts with vitamin B-12 to produce coenzyme A (CoA). When vitamin B-12 deficiencies occur, methylmalonic acid levels increase.
