Stool

Beneficial SCFAs

Optimal Result: 13.6 - 150 micromol/g.

Short chain fatty acids are saturated fatty acids consisting of no more than 6 carbons. The most common forms—acetate, propionate, and butyrate—are also helpful for colon and overall health. Thus, they are called beneficial SCFAs. Beneficial SCFAs exert anti-inflammatory properties in the gastrointestinal tract. They help maintain a barrier in the intestine to prevent “leaky gut.” They also indirectly help people feel full, thus regulating appetite. Beneficial SCFAs are also important for maintaining levels of protective microbes in the gut and inhibiting pathogenic microorganisms. Each short chain fatty acid is measured separately in stool samples. In most cases, however, acetate, propionate, and butyrate are present in a predictable ratio, specifically 60:20:20.

Normal Ranges for beneficial SCFAs:

Analyte (µmol/g)

Low

Mildly Decreased

Optimal

Total SCFA

≤ 48.2

48.3-72.1

≥ 72.2

n-Butyrate

≤ 4.3

4.4-7.7

≥ 7.8

Acetate

≤ 31.4

31.5-46.2

≥ 46.3

Propionate

≤ 9.1

9.2-13.6

≥ 13.7

 

Sources:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735932/

https://www.ncbi.nlm.nih.gov/pubmed?term=7851194

https://www.uptodate.com/contents/clinical-manifestations-diagnosis-and-treatment-of-radiation-proctitis

https://www.nature.com/articles/ijo201584

https://www.ncbi.nlm.nih.gov/pubmed/24388214

What does it mean if your Beneficial SCFAs result is too low?

Low levels of beneficial SCFAs may not directly cause symptoms; however, this state is associated with a number of diseases such as diabetes, obesity, and inflammatory bowel diseases such as ulcerative colitis and Crohn's disease. In most cases, low levels of beneficial SCFAs can be resolved by consuming prebiotics and probiotics. In certain cases, SCFA enemas can be used to directly change the colon content of beneficial SCFAs.

Some specific causes of low beneficial SCFA levels are:

- Metabolic diseases

- Inflammatory bowel disease

- Antibiotic use

- Obesity

- Bowel irradiation

- Diet high in fat and simple sugars

What does it mean if your Beneficial SCFAs result is too high?

The upper limit of normal for beneficial SCFAs in stool is not known.

Understand blood, stool, and urine medical results from your labs.

10 000+ happy clients
100% satisfaction
★★★★★ customer support

Essential Plan


  • Monthly subscription
  • Instant interpretation
  • Use the free self-upload form
  • Additional charge for upload service
  • 2000+ biomarkers explained
  • Recommendations
  • Cancel anytime

Advanced Plan


  • Yearly subscription
  • Instant interpretation
  • We upload five reports for you
  • Use the free self-upload form
  • 2000+ biomarkers explained
  • Nutrition Recommendations
  • Online support
  • Cancel anytime

Own It For Life premium plan


  • No subscription
  • Unlimited access
  • Unlimited storage
  • Instant interpretations
  • We upload ten reports for you
  • Use the free self-upload form
  • 2000+ biomarkers explained
  • Nutrition Recommendations
  • Dedicated support

Healthmatters.io software for professional use.

Welcome to Healthmatters Pro.

Save time on interpreting lab results with the largest database of biomarkers online. In-depth research on any test at your fingertips, all stored and tracked in one place.

Learn More


We implement proven measures to keep your data safe.

At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.

General Data Protection Regulation (GDPR). HIPAA compliance for healthcare professionals
×

Understand Your Lab Result Now

  • Instant interpretation
  • 2000+ biomarkers explained
  • Science-based recommendations
  • Online support
  • Secure and private portal

Get 10% off with promocode:

;