The majority of human tumours strongly over-express the tumour M2 isoform of the glycolytic enzyme Pyruvate Kinase
(M2-PK), which is released from tumour cells and is quantitatively detectable in body fluids. M2-PK is the key regulator of tumour
metabolism and its measurement in faeces identifies gastrointestinaltumours, even in the absence of gastrointestinal bleeding.
M2 Pyruvate Kinase
M2 Pyruvate Kinase
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