Optimal Result: 39 - 100 %.

Asparagine is a dietarily dispensable amino acid synthesized from aspartate and glutamine. Asparagine has three major functions:

1) incorporation into amino acid sequences of proteins;

2) storage form for aspartate (is a required precursor for synthesis of DNA, RNA and ATP); and

3) source of amino groups for production of other dispensable amino acids via trasaminases.

Asparagine in proteins is an attachment site for carbohydrates (N-linked oligosaccharides) to form collagen assembly, enzymes and cell-cell recognition. Asparagine can be readily converted into aspartate, providing asparate on demand for many cellular functions. Aspartate can increase cellular energy production by contributing carbon skeletons to the Citric Acid Cycle. Aspartate is also a component of the urea cycle, which removes excess ammonia. The conversion of asparagine to aspartate involves transfer of the extra amino group from asparagine to another keto acid, forming a dispensable amino acid. In this way, asparagine can be a precursor for many amino acids to be produced on demand to meet cell requirements.

What does it mean if your Asparagine result is too low?

Data from testing over 10,000 physician office patients has found that 22.8% have deficient asparagine function, as indicated by increased lymphocyte growth response after addition of asparagine to the lymphocyte growth media. Significantly increased prevalence of asparagine deficiencies has been detected in two clinical manifestations:

1) fatigue; and

2) immune system stress.

For example, in 75 subjects with rheumatoid arthritis, 32.0% exhibited an asparagine deficiency. There are no published deficiency symptoms for asparagine in the medical literature, partly due to previous lack of adequate assessment tests. Therefore, tentative associates of asparagine deficiencies with clinical complaints of fatigue, and clinical findings of immune dysfunction (autoimmune disorders, severe allergies, infections) have been identified by the MicroNutrient Test for asparagine.

Since asparagine is a dispensable amino acid, no RDA exists. Asparagine is present in all proteins, but is partially degraded into aspartate by heat (cooking), storage or acid. Asparagine supplementation appears safe in modest doses (up to 6 grams daily).

If you can test it, we can track it — all test results, including the ones from your favorite labs.

10 000+ happy clients
100% satisfaction
★★★★★ customer support

Essential Plan


  • Monthly subscription
  • Instant interpretation
  • Use the free self-upload form
  • Additional charge for upload service
  • 2000+ biomarkers explained
  • Recommendations
  • Cancel anytime

Advanced Plan


  • Yearly subscription
  • Instant interpretation
  • We upload five reports for you
  • Use the free self-upload form
  • 2000+ biomarkers explained
  • Nutrition Recommendations
  • Online support
  • Cancel anytime

Own It For Life premium plan


  • No subscription
  • Unlimited access
  • Unlimited storage
  • Instant interpretations
  • We upload ten reports for you
  • Use the free self-upload form
  • 2000+ biomarkers explained
  • Nutrition Recommendations
  • Dedicated support

We implement proven measures to keep your data safe.

At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.

General Data Protection Regulation (GDPR). HIPAA compliance for healthcare professionals