Vitamin B1 (Thiamin) is used by cells to help make energy from foodstuffs. Thiamin pyrophosphate is a cofactor for dehydrogenase enzymes with key roles in cellular energy production.
Thiamin pyrophosphate is required for transketolase activity, which is a component of the pentose phosphate pathway, the sole source for the synthesis of ribose used in synthesis of the nucleic acids (DNA and RNA). These reactions also produce the major source of cellular NADPH (used in fatty acid biosynthesis and other pathways). Thiamin triphosphate is localized in nerve cell membranes, and plays a role in transmission of nervous impulses and acetylcholine synthesis.
Early vitamin B1(thiamin) deficiency leads to clinical signs of:
- Loss of appetite
- Mental depression
- Peripheral Neuropathy
Clinical signs of more severe thiamin deficiency (Wernicke-Korsafoff Syndrome):
- Mental confusion
- Loss of eye coordination
- Loss of fine motor control
Those at risk for vitamin B1(Thiamin) deficiency include:
- Patients suffering from malnutrition, starvation or malabsorptin syndromes
- Patients on restricted diets
- Gastric partitioning surgery
- Prolonged hemodialysis (pregnancy, lactation, fever, infection, trauma)
- Patients with an increased metabolic rate
- Metabolic DisordersRepletion Information:
Dietary sources richest in B1 (per serving) include:
- Nutritional supplements
- Rice Bran
- Nutritional Yeasts
- Wheat Germ
- Legumes (beans, peas, soybeans, lentils)
Own it for life
Our exclusive data entry service is a convenient way to get your results into your private dashboard. Simply attach an image or a file of your lab test results, and one of our qualified data entry team members will add the results for you. We support all sorts of files, whether PDFs, JPGs, or Excel. This service is excellent whether you have a lot of reports to upload or are too busy to do the data entry yourself.
We strive to make the data entry process easy for you. Whether by offering dozens of templates to choose from that pre-populate the most popular laboratory panels or by giving you instant feedback on the entered values. Our data entry forms are an easy, fast, and convenient way to enter the reports yourself. There is no limit on how many lab reports you can upload.
billed every month
Data entry included
$6.60/month billed annually
Data entry included
own it for life
Are You a Health Professional?
Get started with our professional plan
Welcome to Healthmatters Pro.
Save time on interpreting lab results with the largest database of biomarkers online. In-depth research on any test at your fingertips, all stored and tracked in one place. Learn more
Pro Monthly Plus
for health professionals
$75 per month