Monocytes are a type of white blood cell (leukocyte) that plays a key role in immune defense. They circulate in the bloodstream and tissues, identifying and eliminating viruses, bacteria, fungi, and infected cells while signaling other immune cells to respond to infections and injuries.
When needed, monocytes transform into macrophages or dendritic cells:
Monocytes are the largest white blood cells, nearly twice the size of red blood cells. Although they are few in number, they are essential for immune function.
Monocytes fight infections, regulate inflammation, and support immune function. They remain in circulation until needed, then migrate to tissues to differentiate into macrophages or dendritic cells.
Monocytes and macrophages also help eliminate cancer cells and remove harmful foreign substances.
A complete blood count (CBC) measures monocytes in two ways:
Monocytes develop in the bone marrow from blood stem cells. Once mature, they enter the bloodstream and travel to tissues in organs such as the spleen, liver, lungs, and bone marrow, where they monitor for pathogens.
Monocytes are the largest white blood cells, nearly twice the size of red blood cells. Under a microscope, they can be identified by their bilobed (kidney-shaped) nucleus, which floats in a fluid-filled cytoplasm.
A normal monocyte count is 2%–8% of total white blood cells or 200–800 cells per microliter of blood. Levels outside this range may indicate an underlying health condition that requires further evaluation.
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Monocytosis refers to an abnormally high level of monocytes, a type of white blood cell involved in immune defense. While a high monocyte count can indicate an underlying condition, it does not always signal a serious health issue. Your healthcare provider will evaluate your overall health and determine any potential causes.
Monocytosis can be associated with infections, autoimmune diseases, chronic inflammation, blood disorders, and certain cancers. However, it can also result from less serious factors such as stress, intense exercise, or pregnancy.
Monocytosis itself does not usually cause symptoms. Instead, symptoms typically arise from the underlying condition responsible for the increased monocyte levels.
A complete blood count (CBC) is used to detect monocytosis. If monocyte levels are elevated, further tests may be required, such as:
Treatment depends on the underlying cause. Once identified, management strategies may include:
Since a high monocyte count alone is not a disease, addressing the root cause is key to restoring balance in your immune system.
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Low monocyte levels, known as monocytopenia, often result from conditions that lower overall white blood cell counts or treatments that suppress the immune system. Since monocytes play a key role in fighting infections and supporting immune responses, having low levels may increase susceptibility to infections.
Low monocytes do not typically cause symptoms on their own, but the underlying condition can lead to noticeable signs. The most common effect of monocytopenia is frequent infections, which may present as:
Symptoms may also result from other blood cell abnormalities, such as leukopenia (low white blood cells) or anemia (low red blood cells).
Monocytopenia is detected through a complete blood count (CBC). If monocyte levels are low, further tests may be needed to determine the cause, including:
Treatment focuses on managing the underlying condition, preventing infections, and addressing complications.
If an infection develops, prompt treatment with antibiotics, antivirals, or antifungals may be necessary.
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I have been using Healthmatters.io since 2021. I travel all over the world and use different doctors and health facilities. This site has allowed me to consolidate all my various test results over 14 years in one place. And every doctor that I show this to has been impressed. Because with any health professional I talk to, I can pull up historical results in seconds. It is invaluable. Even going back to the same doctor, they usually do not have the historical results from their facility in a graph format. That has been very helpful.
Karin
Advanced Plan Member since 2020
What fantastic service and great, easy-to-follow layouts! I love your website; it makes it so helpful to see patterns in my health data. It's truly a pleasure to use. I only wish the NHS was as organized and quick as Healthmatters.io. You've set a new standard for health tracking!
Paul
Healthmatters Pro Member since 2024
As a PRO member and medical practitioner, Healthmatters.io has been an invaluable tool for tracking my clients' data. The layout is intuitive, making it easy to monitor trends and spot patterns over time. The ability to customize reports and charts helps me present information clearly to my clients, improving communication and outcomes. It's streamlined my workflow, saving me time and providing insights at a glance. Highly recommended for any practitioner looking for a comprehensive and user-friendly solution to track patient labs!
Healthmatters is a highly-personalized health dashboard.
Instead of searching for your lab results in different places or tracking them down from different providers, Healthmatters houses, organizes, and interprets them all in one central location.
With a Healthmatters account, you can dive into the details of each biomarker and gain insights into the meaning behind your medical test data, anytime, anywhere.
For our professional users, Healthmatters provides intuitive tools that not only streamline analysis but also save valuable time when delving into your client's lab report history.
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If you are still determining whether Healthmatters support your lab results, the rule is that if you can test it, you can upload it to Healthmatters.
While we work with many popular labs, we welcome reports from lots of other places too.
It's as simple as this: if you can get a test done, you can upload it to Healthmatters and we can interpret results from any lab out there. If laboratories can analyze it, we can interpret it.
If you’re on the hunt for a specific biomarker, contact us and we'll add it to our database. Anything from blood, urine, saliva, or stool can be uploaded, understood, and tracked with your Healthmatters account.
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For those who prefer assistance, we offer a "Data entry service" to help you input your data. Simply attach an image or file of your lab test results, and a qualified team member from our data entry team will add the results for you.
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We’ve crafted multiple ways for you to navigate your data, whether you're glancing at a single report or delving into your historical test reports.
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Yes, you can. When entering values for the biomarker, you will see an "Edit Range" button. Click this button, and you'll have the option to enter a custom range.
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ABSOLUTE BAND NEUTROPHILS, ABSOLUTE METAMYELOCYTES, ABSOLUTE MYELOCYTES, Atypical Lymphocytes, Atypical Lymphocytes (x10*9/L), Band Neutrophils (%), Basophils (Absolute), Basophils (Percent), Eosinophils "Eos" (Absolute), Eosinophils "Eos" (Percent), Lymphocytes "Lymphs" (Absolute), Lymphocytes "Lymphs" (Percent), METAMYELOCYTES (%), MID#, MID%, Monocytes (Absolute), Monocytes (Percent), Myelocytes, Neut/Lymph Ratio, Neutrophils (Absolute), Neutrophils (Percent), Polymorphs, Polymorphs (Absolute), Segmented Neutrophils, Segmented Neutrophils (Percent)
