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Tryptophan

Amino Acid Profile, Qn (Plasma), LabCorp

Optimal range:   23.5 - 93 umol/L

Tryptophan is an essential amino acid required for the production of the neurotransmitter serotonin.

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Tryptophan

OMX Organic Metabolomics / Diagnostic Solutions, Diagnostic Solutions Laboratory | GI-MAP & Food Sensitivity Tests

Optimal range:   10.1 - 74.3 nmol/mg Creatinine

Three pathways:

- Kynurenine Pathway (primary pathway) – leading to niacin production

- Serotonin/Melatonin

- Indoles

Tryptophan is involved in serotonin production via vitamin B6-dependent pathways resulting in the intermediate 5-hydroxytryptophan (5-HTP).

5-HTP is often used as a supplement for serotonin formation instead of tryptophan, which can be quickly metabolized in other pathways. Serotonin is further metabolized to melatonin via methylation. Because of these downstream conversions, therapeutic administration of 5-HTP has been shown to be effective for depression, fibromyalgia, binge eating associated with obesity, chronic headaches, and insomnia.

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TRYPTOPHAN

Urine

Amino Acid Analysis, LC/MS, Quest Diagnostics

Optimal range:   2 - 16 mmol/mol creatinine

Tryptophan is involved in serotonin production via vitamin B6-dependent pathways resulting in the intermediate 5-hydroxytryptophan (5-HTP).

5-HTP is often used as a supplement for serotonin formation instead of tryptophan, which can be quickly metabolized in other pathways. Serotonin is further metabolized to melatonin via methylation. Because of these downstream conversions, therapeutic administration of 5-HTP has been shown to be effective for depression, fibromyalgia, binge eating associated with obesity, chronic headaches, and insomnia.

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Tryptophan

ZRT Laboratory (Urinary Neurotransmitters), ZRT Laboratory

Optimal range:   3970 - 8450 µg/g creatinine

Tryptophan is an amino acid that generates serotonin, melatonin, and kynurenine derivatives.

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Tryptophan (Plasma)

Amino Acids 40 Profile, Genova Diagnostics

Optimal range:   31 - 83 µmol/L , 3.1 - 8.3 µmol/dL

Tryptophan is an essential amino acid required for the production of the neurotransmitter serotonin.

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Tryptophan (Plasma)

OMX Organic Metabolomics / Diagnostic Solutions, Diagnostic Solutions Laboratory | GI-MAP & Food Sensitivity Tests

Optimal range:   36.9 - 87.1 nmol/ML

Three pathways:

- Kynurenine Pathway (primary pathway) – leading to niacin production

- Serotonin/Melatonin

- Indoles

Tryptophan is involved in serotonin production via vitamin B6-dependent pathways resulting in the intermediate 5-hydroxytryptophan (5-HTP).

5-HTP is often used as a supplement for serotonin formation instead of tryptophan, which can be quickly metabolized in other pathways. Serotonin is further metabolized to melatonin via methylation. Because of these downstream conversions, therapeutic administration of 5-HTP has been shown to be effective for depression, fibromyalgia, binge eating associated with obesity, chronic headaches, and insomnia.

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Tryptophan (Urine)

Amino Acids Analysis, Genova Diagnostics

Optimal range:   5 - 53 micromol/g creatinine

Tryptophan is an essential amino acid required for the production of the neurotransmitter serotonin.

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Tryptophan/LNAA

3102 ION (Blood/Urine) Amino Acids 40, Genova Diagnostics

Optimal range:   0.04 - 0.09 Ratio

Tryptophan is an essential amino acid, a subunit in protein molecules and a precursor to serotonin. The brain uses tryptophan to produce serotonin, a neurotransmitter largely responsible for feelings of happiness and well-being.

Tryptophan cannot be synthesised by the body and must be obtained through diet.

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Tryptophan/LNAA

Blood

NutriStat Basic Profile, US BioTek

Optimal range:   0.12 - 0.35 Ratio

Tryptophan is an essential amino acid, a subunit in protein molecules and a precursor to serotonin. The brain uses tryptophan to produce serotonin, a neurotransmitter largely responsible for feelings of happiness and well-being.

Tryptophan cannot be synthesised by the body and must be obtained through diet.

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Tryptophan/LNAA (Genova)

Amino Acids 40 Profile, Genova Diagnostics

Optimal range:   0.1 - 0.11 Ratio

Tryptophan is an essential amino acid, a subunit in protein molecules and a precursor to serotonin. The brain uses tryptophan to produce serotonin, a neurotransmitter largely responsible for feelings of happiness and well-being.

Tryptophan cannot be synthesised by the body and must be obtained through diet.

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Tryptophane

Urinary Amino Acids (Synlab), SYNLAB

Optimal range:   0 - 5 mmol/mol creatinine

Tryptophan is involved in serotonin production via vitamin B6-dependent pathways resulting in the intermediate 5-hydroxytryptophan (5-HTP).

5-HTP is often used as a supplement for serotonin formation instead of tryptophan, which can be quickly metabolized in other pathways. Serotonin is further metabolized to melatonin via methylation. Because of these downstream conversions, therapeutic administration of 5-HTP has been shown to be effective for depression, fibromyalgia, binge eating associated with obesity, chronic headaches, and insomnia.

LEARN MORE

Tryptophane

Blood

NutriStat Basic Profile, US BioTek

Optimal range:   61.1 - 211 umol/L

Tryptophane is involved in serotonin production via vitamin B6-dependent pathways resulting in the intermediate 5-hydroxytryptophan (5-HTP).

5-HTP is often used as a supplement for serotonin formation instead of tryptophan, which can be quickly metabolized in other pathways. Serotonin is further metabolized to melatonin via methylation. Because of these downstream conversions, therapeutic administration of 5-HTP has been shown to be effective for depression, fibromyalgia, binge eating associated with obesity, chronic headaches, and insomnia.

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TSH

Blood

Blood Spot Thyroids, ZRT Laboratory

Optimal range:   0.5 - 3 uU/mL

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TSH

NutriStat, NutriPATH

Optimal range:   0.5 - 5 mIU/L

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TSH RECEPTOR AB

NutriStat, NutriPATH

Optimal range:   0 - 1.8 IU/L

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TSH Receptor Antibody (TBII)

Metabolic Health

Optimal range:   0 - 1 U/L

TSH receptor antibodies are antibodies that are often present in the serum of patients with Graves’ disease that are directed against the TSH receptor, often causing stimulation of this receptor with resulting hyperthyroidism.

What is Graves’ disease?

Graves' disease is an autoimmune disorder that can cause hyperthyroidism, or overactive thyroid. The thyroid is a small, butterfly-shaped gland in the front of your neck. Thyroid hormones control the way your body uses energy, so they affect nearly every organ in your body, even the way your heart beats.

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TSI - Thyroid-Stimulating Immunoglobulin, Serum

Quest Diagnostics, Quest Diagnostics

Optimal range:   0 - 140 %

TSI stands for thyroid stimulating immunoglobulin. TSIs are antibodies that tell the thyroid gland to become more active and release excess amounts of thyroid hormone into the blood. A TSI test measures the amount of thyroid stimulating immunoglobulin in your blood.

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TTG IGA

Serum

Celiac Comprehensive Panel

Optimal range:   0 - 14.9 U/mL

The TTG IGA marker is a crucial element in the diagnostic process for celiac disease, offering a high degree of accuracy in identifying this autoimmune disorder. Tissue Transglutaminase (TTG) is an enzyme targeted by the immune system in celiac disease, leading to the production of Immunoglobulin A (IGA) antibodies against it. This specific immune response forms the basis of the TTG IGA test, widely regarded as the first-line screening tool in diagnosing celiac disease. Its effectiveness lies in its ability to detect these antibodies, which are typically elevated in individuals with celiac disease, especially in those who have not yet started a gluten-free diet.

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Tumor Necrosis Factor

Immune System

Optimal range:   0 - 2.2 pg/mL

Tumour Necrosis Factor alpha (TNF alpha), is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and is responsible for a diverse range of signalling events within cells, leading to necrosis or apoptosis. The protein is also important for resistance to infection and cancers.

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Tumor necrosis factor alpha (TNF-alpha)

Cytokine assay panel for immune profile, SYNLAB

Optimal range:   0 - 16.1 pg/mL

Results are used to understand the pathophysiology of immune, infectious, or inflammatory disorders, or may be used for research purposes.

Tumor necrosis factor-α (cachectin) and tumor necrosis factor-β (lymphotoxin) are two closely related proteins that share sequence homology of 34% in their amino acid sequence. Both mediators act on their target cells via the same receptors and, therefore, show similar, but not identical, biological effects. Under denaturing conditions TNF-α is a 17-kilodalton, nonglycosylated protein. The biologically active form of TNF-α is a trimer. Besides this soluble form of TNF-α, a 28-kilodalton membrane-bound form occurs on cell surfaces of TNF-producing cells, which may serve as a pool for soluble TNF-α and can be proteolytically cleaved from the cell surface.

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