Bifidobacterium species

Optimal result: 6.7 – 1000 x10^5 CFU/g

- Increased levels of Bifidobacterium spp. have been seen in obese compared to lean/overweight subjects.

- The amount of Bifidobacterium has been measured at lower levels after weight-loss and gastric bypass surgery.

- Lower levels also measured in people with IBD and IBS.

- Lower levels seen in type 2 diabetes

- Lower levels seen in pediatric allergy

- Lower levels seen in autism

- Infants with lower Bifidobacterium may have increased risk for weight gain in childhood

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Bifidobacterium longum is a Gram-positive, catalase-negative, rod-shaped bacterium present in the human gastrointestinal tract and one of the Bifidobacterium species. It can induce and regulate immune responses, reduce the expression of inflammatory cytokines, and maintain the normal intestinal barrier function. Bifidobacterium longum is a clinically effective, well-established, multifunctional probiotic that has a long history of human use in alleviating gastrointestinal, immunological, and infectious diseases such as constipation, antibiotic associated diarrhoea, irritable bowel syndrome and ulcerative colitis. Low levels may be associated with irritable bowel syndrome, asthma, autism, depressive disorder and with pathogenic bacteria infection.

Treatment may involve the use of Bifidobacterium longum containing probiotics and treatment of any intestinal infections.

A common component of the microbiota of the human gastrointestinal tract and in particular are amongst the first bacterial colonizers of the intestine.

Bifidobacterium bacteria are regarded as a vital part to infant health. They are supposed to prevent the growth of disease-causing bacteria. Mother's milk can help increase the development of Bifidobacterium. As the microbiome matures, Bifidobacterium decreases, and although it is a genus commonly found in the adult gut, its overall level generally makes up less than 3% of an individual’s total bacterial load.

The Bifidobacterium species are non-pathogenic, and are deliberately added to some food products because of their beneficial probiotic health effects, such as:

- better lactose tolerance

- the prevention of diarrhea

- a reduction in food allergies

- the inhibition of the growth of pathogenic organisms

References:

- Low Relative Abundances of the Mucolytic Bacterium Akkermansia muciniphila and Bifidobacterium spp. in Feces of Children with Autism [L]

- Bifidobacteria: their impact on gut microbiota composition and their applications as probiotics in infants. [L]

- Nursing our microbiota: molecular linkages between bifidobacteria and milk oligosaccharides. [L]

Bifidobacterium species
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