Thyroid-Stimulating Hormone (TSH)

Metabolic Health

A healthy result should fall into the range 0.5 - 4.5 mIU/L, or 0.50 - 4.50 IU/L.

TSH stands for thyroid stimulating hormone, though it is sometimes called thyrotropin or thyrotropic hormone. TSH stimulates the thyroid gland to produce thyroid hormone, which is is critical for the proper function of virtually every cell in the body. TSH is released by the pituitary gland after the gland has been stimulated by thyroid releasing hormone (TRH), which is secreted by the hypothalamus. Thyroid hormone provides negative feedback on the hypothalamus and/or the pituitary to reduce thyroid hormone production and release. TSH measurements are important for diagnosing hypothyroidism and hyperthyroidism. TSH may be measured in conjunction with total thyroxine (T4), total triiodothyronine (T3), free T4, free T3, and reverse T3 concentrations in the serum.

Normal Ranges for TSH:

  • Children
    •   1-2 Days 3.20-34.60 mIU/L
    •   3-4 Days 0.70-15.40 mIU/L
    •   5 Days-4 Weeks 1.70-9.10 mIU/L
    •   1-11 Months 0.80-8.20 mIU/L
    •   1-19 Years 0.50-4.30 mIU/L
  • Adult (non-pregnant) 0.40-4.50 mIU/L
  • Pregnancy  
    •   First Trimester 0.26-2.66 mIU/L
    •   Second Trimester 0.55-2.73 mIU/L
    •   Third Trimester 0.43-2.91 mIU/L

 

Sources:

http://www.uptodate.com/contents/thyroid-hormone-synthesis-and-physiology

http://www.ncbi.nlm.nih.gov/pubmed/2194786

http://www.uptodate.com/contents/laboratory-assessment-of-thyroid-function

http://www.questdiagnostics.com/testcenter/TestDetail.action?ntc=899

http://www.uptodate.com/contents/disorders-that-cause-hypothyroidism

http://www.uptodate.com/contents/disorders-that-cause-hyperthyroidism

http://www.ncbi.nlm.nih.gov/pubmed/21048053

http://www.nejm.org/doi/full/10.1056/NEJMcp0801880

http://www.uptodate.com/contents/disorders-that-cause-hyperthyroidism

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