Metabolic Health

Reverse T3, Serum

Optimal Result: 9.2 - 24.1 ng/dL.

Reverse T3 is a biologically inactive thyroid hormone; however, it does block the conversion of thyroxine (T4) to triiodothyronine (T3). Higher levels of reverse T3 can decrease the effect of thyroid hormone. While reverse T3 does not act like other thyroid hormones T3 and T4, it may play a role in brain development. Serum reverse T3 levels are helpful in distinguishing between thyroid disease and disease not related to the thyroid gland. Serum reverse T3 is often helpful when total T3, total T4, free T4, and TSH levels provide expected results or further investigation is needed. Because reverse T3 can be altered by illness, it is not useful in hospitalized patients.

Normal Ranges for serum reverse T3:

10-24 ng/dL

What does it mean if your Reverse T3, Serum result is too low?

Decreased rT3 levels in the serum are uncommon. When it occurs, it usually happens in people with hypothyroidism or those being treated with growth hormones or steroids. Elevated rT3 does not specifically cause symptoms, but the thing that caused the increased rT3 level may cause its own symptoms.

Some specific causes of low reverse T3 are:

  • Central hypothyroidism
  • Growth hormone
  • Glucocorticoids
  • X-linked monocarboxylate transporter 8 deficiency

What does it mean if your Reverse T3, Serum result is too high?

Elevated reverse T3 (rT3) levels can be caused by almost any serious or prolonged illness. Low blood oxygen levels strongly increase reverse T3 levels in the serum. People with severe malnutrition (especially a lack of carbohydrates), severe diabetes, kidney, or liver disease have increased levels of rT3. Elevated rT3 does not specifically cause symptoms, but the disease that caused the increased rT3 level causes its own symptoms.

Some specific causes of high reverse T3 are:

  • Hyperthyroidism
  • Non-thyroidal illness syndrome/Euthyroid sick syndrome
  • Cirrhosis
  • Chronic renal failure
  • Protein-calorie malnutrition
  • Acute febrile illness
  • Carbohydrate deprivation
  • Uncontrolled diabetes mellitus
  • Amiodarone
10 000+ happy clients
100% satisfaction
★ ★ ★ ★ ★ customer support

Understand blood, stool, and urine medical results from all your laboratories.

Get Started With Our Personal Plan

Advanced Plan

  • ✓ Yearly subscription
  • ✓ Five free uploads
  • ✓ Cancel anytime
  • ✓ Instant interpretations
  • ✓ Use the free self-upload form
  • ✓ 3000+ biomarkers explained
  • ✓ Nutrition Recommendations
  • ✓ Dedicated support
  • ✓ Yearly subscription
  • ✓ Five free uploads
  • ✓ Cancel anytime
$79 per year
  • ✓ Instant interpretations
  • ✓ Use the free self-upload form
  • ✓ 3000+ biomarkers explained
  • ✓ Nutrition Recommendations
  • ✓ Dedicated support

Unlimited Plan

  • ✓ No subscription
  • ✓ Ten free uploads
  • ✓ Unlimited access
  • ✓ Instant interpretations
  • ✓ Use the free self-upload form
  • ✓ 3000+ biomarkers explained
  • ✓ Nutrition Recommendations
  • ✓ Dedicated support
  • ✓ No subscription
  • ✓ Ten free uploads
  • ✓ Unlimited access
$250 full version

Are You a Health Professional?

Get started with our professional plan

Welcome to Healthmatters Pro.

Save time on interpreting lab results with the largest database of biomarkers online. In-depth research on any test at your fingertips, all stored and tracked in one place. Learn more

Pro Plan

for health professionals

  • ✓ Track multiple clients results
  • ✓ No setup fees
  • ✓ No hidden costs
  • ✓ Cancel anytime
  • ✓ Instant interpretations
  • ✓ Use the free template forms
  • ✓ 3000+ biomarkers explained
  • ✓ Additional team member $25
  • ✓ Personal training and support

$45 per month

Use promo code to save 10% off any plan.


We implement proven measures to keep your data safe.

At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.

×

Understand Your Lab Result Now

  • Instant interpretation
  • 3000+ biomarkers explained
  • Science-based recommendations
  • Online support
  • Secure and private portal

Get 10% off with promocode: