Reverse T3, Serum

Metabolic Health

A healthy result should fall into the range 8 - 25 ng/dL.

Reverse T3 is a biologically inactive thyroid hormone; however, it does block the conversion of thyroxine (T4) to triiodothyronine (T3). Higher levels of reverse T3 can decrease the effect of thyroid hormone. While reverse T3 does not act like other thyroid hormones T3 and T4, it may play a role in brain development. Serum reverse T3 levels are helpful in distinguishing between thyroid disease and disease not related to the thyroid gland. Serum reverse T3 is often helpful when total T3, total T4, free T4, and TSH levels provide expected results or further investigation is needed. Because reverse T3 can be altered by illness, it is not useful in hospitalized patients.

Normal Ranges for serum reverse T3:

10-24 ng/dL

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