Thyroid Peroxidase Antibodies (Anti-TPO Ab)

Metabolic Health

A healthy result should fall into the range 0 - 9 IU/ml.

Thyroid peroxidase (TPO) is an enzyme that is critical for to thyroid hormone synthesis in the thyroid gland. Thyroid peroxidase (TPO) antibodies bind to and block the action of TPO, resulting in decreases in thyroid hormone levels. The presence of TPO antibodies in the blood is abnormal and usually indicates thyroid disease. The thyroid peroxidase (TPO) antibodies test is usually ordered after thyroid abnormalities have been detected with some other type of testing, such as TSH and free T4. It is usually ordered with thyroglobulin antibody testing.

Normal range for Thyroid Peroxidase Antibodies:

Quest Diagnostics: <9 IU/mL

LabCorp: adults: <34 IU/mL

Other age ranges by LabCorp: 

Age

Range (IU/mL)

0 to 6 d

0−117

7 d to 3 m

0−47

4 to 11 m

0−32

1 to 5 y

0−13

6 to 10 y

0−18

11 to 19 y

0−26

>19 y

0−34

 

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