Metabolic Health

Tri iodothyronine (T3) Uptake

Optimal Result: 23.4 - 42.7 %.

A T3 resin uptake (also called a T3 uptake or T3RU) is a blood test performed as part of an evaluation of thyroid function.

The T3 resin uptake is used by doctors to estimate the amount of TBG in the blood, and how much T4 and T3 in the blood is free form and available to affect the body.

The thyroid is a gland in the neck that produces the hormones that help regulate many body processes, including the following:

- growth,

- energy balance,

- body temperature,

- and heart rate.

Thyroid function involves the interaction of many hormones, including triiodothyronine (T3) and thyroxine (T4). Both of these hormones exist in two forms in the blood. The more abundant forms are bound to a carrier protein called thyroxin-binding globulin (TBG), which helps transport the hormones through the body. The less abundant forms circulate unattached or "free." Only the free forms of the thyroid hormones (free T4 and free T3) are available to affect body processes.

If there's either too much or too little TBG in the blood, the measurements of total T3 and T4 levels will be affected, which can make it difficult for doctors to tell whether a person actually has a thyroid problem without also knowing the results of the T3 resin uptake.

Some people have an inherited condition that involves high TBG levels despite normal thyroid function.

What does it mean if your Tri iodothyronine (T3) Uptake result is too low?

Lower-than-normal levels may indicate:

- Acute hepatitis (liver disease)

- Pregnancy

- Hypothyroidism

- Use of estrogen

What does it mean if your Tri iodothyronine (T3) Uptake result is too high?

Higher-than-normal levels may indicate:

- Kidney failure

- Overactive thyroid (hyperthyroidism)

- Nephrotic syndrome

- Protein malnutrition

Understand blood, stool, and urine medical results from your labs.

10 000+ happy clients
100% satisfaction
★★★★★ customer support

Essential Plan


  • Monthly subscription
  • Instant interpretation
  • Use the free self-upload form
  • Additional charge for upload service
  • 2000+ biomarkers explained
  • Recommendations
  • Cancel anytime

Advanced Plan


  • Yearly subscription
  • Instant interpretation
  • We upload five reports for you
  • Use the free self-upload form
  • 2000+ biomarkers explained
  • Nutrition Recommendations
  • Online support
  • Cancel anytime

Own It For Life premium plan


  • No subscription
  • Unlimited access
  • Unlimited storage
  • Instant interpretations
  • We upload ten reports for you
  • Use the free self-upload form
  • 2000+ biomarkers explained
  • Nutrition Recommendations
  • Dedicated support

Healthmatters.io software for professional use.

Welcome to Healthmatters Pro.

Save time on interpreting lab results with the largest database of biomarkers online. In-depth research on any test at your fingertips, all stored and tracked in one place.

Learn More


We implement proven measures to keep your data safe.

At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.

General Data Protection Regulation (GDPR). HIPAA compliance for healthcare professionals
×

Understand Your Lab Result Now

  • Instant interpretation
  • 2000+ biomarkers explained
  • Science-based recommendations
  • Online support
  • Secure and private portal

Get 10% off with promocode:

;