Solobacterium moorei is an intriguing and less commonly known marker in the analysis of gut microbiota. This bacterium belongs to the Clostridia class and is a Gram-positive, anaerobic species. It has been relatively recently identified and characterized in the context of human gut flora. Solobacterium moorei is noteworthy for its association with oral and gastrointestinal malodor, as it is known to produce volatile sulfur compounds (VSCs) which are often linked to conditions such as halitosis.

Anti-soluble liver antigen antibodies are detected in 10% - 30% of patients with type 1 autoimmune hepatitis (AIH), but not in patients with type 2 AIH, primary sclerosing cholangitis or primary biliary cirrhosis.

Soluble transferrin receptor (sTfR) is a blood marker that reflects how strongly your body is trying to pull iron into cells, especially developing red blood cells in the bone marrow. It is often used to help evaluate iron deficiency and to distinguish “true” iron deficiency from inflammation-related changes in other iron tests (like ferritin). sTfR can be particularly helpful when ferritin is hard to interpret, such as during infection, chronic inflammation, or certain chronic diseases.

The presence of antibodies to Sorghum is an indication of food immune reactivity. The offending food and its known cross-reactive foods should be eliminated from the diet. Sorghum flour, although difficult to process, is becoming a popular alternative flour to use in gluten-free baking. A study on the effects of Sorghum in celiac patients showed that the flour was not antigenic. If a recently diagnosed gluten-reactive patient results with high levels of antibodies against Sorghum, it is most likely due to the late introduction of the food to the patient’s diet, rather than a gluten-associated reaction.

The presence of antibodies to Soy is an indication of food immune reactivity. The offending food and its known cross-reactive foods should be eliminated from the diet. Soy allergy/intolerance is becoming more common as more people begin to seek a healthy protein-rich food. Additionally, patients with immediate or delayed immune reactivities should not only avoid ingesting the food, but should also abstain from using topical products that contain Soy.

The presence of salivary antibodies to Soy is an indication of loss of mucosal tolerance and the onset of food immune reactivity. The offending food and its known cross-reactive foods should be eliminated from the diet. Soy allergy/intolerance is becoming more common as more people begin to seek a healthy protein-rich food. Additionally, patients with immediate or delayed sensitivities should not only avoid ingesting the food, but should also abstain from using topical products that contain Soy.

Elevated antibody levels can be clinically significant — while the antibodies themselves don’t destroy anything, they do trigger an inflammatory response that can cause significant destruction of tissue and resulting symptoms. This response is not necessarily dependent on antibody levels. However, an equivocal result may mean you are just beginning to exhibit an immune reaction, so this is an important time to take measures to support the body in damping immune reactivity.

Special Stains Test is a lab test performed on a skin sample (biopsy) to determine the pathology and confirm there is a skin disease present. It may also be used to monitor the effects of treatment of the skin disease.

The speckled pattern in ANA (Antinuclear Antibody) testing is one of the most common and diagnostically significant patterns, characterized by its distinctive, fine or coarse speckled appearance under a fluorescence microscope. This pattern indicates the presence of antibodies targeting various extractable nuclear antigens (ENAs), including but not limited to Smith (Sm) antigen, ribonucleoprotein (RNP), SS-A (Ro), and SS-B (La). The diversity of these antigens means that the speckled pattern is associated with a range of autoimmune disorders, most notably systemic lupus erythematosus (SLE), Sjögren's syndrome, mixed connective tissue disease (MCTD), and systemic sclerosis.