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Lyme Disease Serology

Reference range:   Positive, Negative

Two types of antibodies are detected in the Western blot test.

IgM antibodies reflect a relatively recent infection. IgG antibodies in contrast are a sign of an older infection. 

IgM antibodies usually disappear after eight weeks post-exposure. 
IgG remains in the serum for a very long time. 

In the Western blot test there are three bands for IgM and 10 bands for IgG.

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Lyme Testing

Reference range:   Negative, Positive

The Lyme IgM Line Blot Interpretation (Interp.) marker is a diagnostic test marker used to assess the presence of specific antibodies called IgM antibodies in a patient's blood.

The IgM Line Blot Interp. marker helps in the diagnosis of Lyme disease by detecting IgM antibodies produced by the immune system in response to an infection with the bacterium Borrelia burgdorferi, which is the causative agent of Lyme disease. IgM antibodies are typically produced during the early stages of infection, usually within a few weeks after exposure to the bacteria.

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Lyme Testing

Optimal range:   0 - 0.91 index

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Lyme Disease Serology

Reference range:   Non-Reactive, Reactive

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Lyme Disease Serology

Reference range:   Positive, Negative

The Lyme disease blood test looks for antibodies in the blood to the bacteria that causes Lyme disease. The test is used to help diagnose Lyme disease.

Lyme disease is caused by bacteria called Borrelia burgdorferi. Blacklegged ticks carry these bacteria. The ticks pick up the bacteria when they bite mice or deer that are infected with Lyme disease. You can get the disease if you are bitten by an infected tick, mostly in northeastern states and on the West Coast. The good news is that usually a tick has to be attached to your body for 24 to 36 hours to infect you. The bad news is that blacklegged ticks are so small they're almost impossible to see.

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Lyme Testing

Optimal range:   0 - 0 Units

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Lymphocyte Subset Panel 2

Optimal range:   7 - 14 %

CD1656 are an important NK (Natural killer) cell subset.

- NK cells are best known for killing virally infected cells, and detecting and controlling early signs of cancer. As well as protecting against disease, specialized NK cells are also found in the placenta and may play an important role in pregnancy.

- Natural killer T (NKT) cells represent a specialized T-cell population that is distinct from conventional T cells. They express an invariant T-cell receptor (TCR) that recognizes self and bacterial glycosphingolipid antigens presented by the MHC class I-like molecule, CD1d.

- Human natural killer (NK) cells can be subdivided in several subpopulations on the basis of the relative expression of the adhesion molecule CD56 and the activating receptor CD16. 

- NK cells serve an important role in host defense against viral infections, as well as tumor surveillance. They are also a component of the adaptive immune response through cytokine production.

- NK cell functions are governed by a balance between activating receptors and inhibitory receptors.

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Lymphocyte Subset Panel 2

Optimal range:   50 - 375 #/cumm

CD1656 are an important NK (Natural killer) cell subset.

- NK cells are best known for killing virally infected cells, and detecting and controlling early signs of cancer. As well as protecting against disease, specialized NK cells are also found in the placenta and may play an important role in pregnancy.

- Natural killer T (NKT) cells represent a specialized T-cell population that is distinct from conventional T cells. They express an invariant T-cell receptor (TCR) that recognizes self and bacterial glycosphingolipid antigens presented by the MHC class I-like molecule, CD1d.

- Human natural killer (NK) cells can be subdivided in several subpopulations on the basis of the relative expression of the adhesion molecule CD56 and the activating receptor CD16. 

- NK cells serve an important role in host defense against viral infections, as well as tumor surveillance. They are also a component of the adaptive immune response through cytokine production.

- NK cell functions are governed by a balance between activating receptors and inhibitory receptors.

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Micronutrient (Vibrant America), Vibrant America

Optimal range:   1.18 - 3.74 x10E3/uL

The "Lymphocyte Count" is an important marker on the Micronutrient panel from VibrantAmerica. Lymphocytes are a type of white blood cell crucial for the body's immune system. They play a significant role in defending the body against infections, viruses, and other harmful invaders. The lymphocyte count measures the number of lymphocytes present in your blood. A healthy lymphocyte count indicates a well-functioning immune system, capable of effectively fighting off infections and diseases. Conversely, an abnormal lymphocyte count, whether too high or too low, can signal underlying health issues. For example, a low lymphocyte count might indicate a compromised immune system, making the body more susceptible to infections and illnesses, while a high count could suggest the presence of an ongoing infection or an autoimmune disorder where the body mistakenly attacks its own tissues. Regular monitoring of your lymphocyte count through panels like the Micronutrient panel from VibrantAmerica helps in early detection and management of potential health problems, ensuring that your immune system remains robust and effective in protecting your overall health.

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White Blood Cell Differential Test

Optimal range:   0.7 - 3.1 x10E3/uL , 700 - 3100 cells/uL

Lymphocytes are a type of white blood cell that plays a key role in the immune system. They help the body detect and fight infections caused by viruses, bacteria, and other harmful invaders. Lymphocytes are produced in the bone marrow and circulate through the blood and lymphatic system to monitor the body for potential threats.

There are three main types of lymphocytes: T cells, which regulate immune responses and destroy infected cells; B cells, which produce antibodies that target pathogens; and natural killer (NK) cells, which rapidly eliminate virus-infected or abnormal cells. Together, these cells help protect the body and create immune memory after infections or vaccinations.

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White Blood Cell Differential Test

Optimal range:   20 - 40 %

Lymphocytes (shown as "Lymphs" or "Lymphs %" on a CBC report) are a type of white blood cell central to immune function. The normal range is 20–40% of total white blood cells. A low percentage (lymphopenia) may indicate immune suppression, recent illness, or medication effects. A high percentage (lymphocytosis) most commonly reflects an active viral infection. Results are interpreted alongside the absolute lymphocyte count and other white blood cell differential values.

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Lymphocytes, %

Synovial fluid

Cell Count and Differential, Synovial Fluid, Quest Diagnostics

Optimal range:   0 - 74 %

Lymphocytes are a type of white blood cell that plays a key role in the immune system. They are responsible for recognizing and combating infections, including viral and autoimmune diseases.

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Lymphocytes, CSF

Cerebrospinal fluid

Cerebrospinal Fluid (CSF) Analysis

Optimal range:   40 - 80 %

Cerebrospinal fluid (CSF) is a clear liquid that cushions and surrounds the brain and spinal cord. It helps support the venous structures around the brain, and it’s important in brain homeostasis and metabolism. This fluid is continually replenished by the choroid plexus in the brain and absorbed into the bloodstream. The body completely replaces CSF every few hours.

The WBC count seen in normal adult CSF is comprised of approximately 70 percent lymphocytes and 30 percent monocytes. There are two forms of lymphocytes: B cells, which make antibodies, and T cells, which recognize and remove foreign substances.

Lymphocytes, when found in cerebrospinal fluid (CSF) as part of a Cell Count and Differential panel, provide critical insights into the immunological and pathological status of the central nervous system (CNS). The presence and concentration of lymphocytes in CSF are indicative of the immune response within the CNS and can be a marker for various conditions, including infections, autoimmune disorders, and malignancies.

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Lymphs, CSF

Cerebrospinal fluid

Cerebrospinal Fluid (CSF) Analysis

Optimal range:   40 - 80 %

Lymphocytes (Lymphs) in cerebrospinal fluid (CSF) are an important marker often assessed during lab tests to evaluate the health of the central nervous system. Lymphocytes are a type of white blood cell that plays a critical role in the immune response. In the CSF, elevated levels of lymphs can indicate inflammation or infection, such as viral meningitis, autoimmune diseases, or certain cancers like lymphoma. Normal lymphocyte levels in the CSF typically suggest a healthy central nervous system. However, deviations from normal ranges may prompt further investigation to determine the underlying cause of the immune response within the brain and spinal cord.

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Lysine

Blood

NutriStat Basic Profile, US BioTek

Optimal range:   139 - 437 umol/L

Lysine is a nutritionally essential amino acid abundant in meat, fish, fowl, and legumes and is needed for formation of body proteins and enzymes.

Lysine can be methylated using S-adenosylmethionine (SAM) to synthesize carnitine, which is needed for fatty acid oxidation. Lysine also generates Acetyl CoA for use in the citric acid cycle. Lysine, proline, hydroxyproline, and vitamin C are important in the synthesis of collagen for skin, bones, tendons and cartilage.

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LYSINE

Urine

Amino Acid Analysis, LC/MS, Quest Diagnostics

Optimal range:   4 - 69 mmol/mol creatinine

Lysine is a nutritionally essential amino acid abundant in meat, fish, fowl, and legumes and is needed for formation of body proteins and enzymes.

Lysine can be methylated using S-adenosylmethionine (SAM) to synthesize carnitine, which is needed for fatty acid oxidation. Lysine also generates Acetyl CoA for use in the citric acid cycle. Lysine, proline, hydroxyproline, and vitamin C are important in the synthesis of collagen for skin, bones, tendons and cartilage.

L-lysine supplementation has also been studied for herpes simplex treatment and prophylaxis and may be beneficial.

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