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Optimal range: 11 - 57 qmol/dL
Proline is a nonessential amino acid. It contains a secondary α-imino group and is sometimes called an α-imino acid. Proline, and its metabolite hydroxyproline, constitute a third of the total amino acids found in collagen. Lysine, proline, hydroxyproline, and vitamin C are all important in the synthesis of collagen for skin, bones, tendons, and cartilage. Proline is abundant in meat, bone meal, poultry, salmon, wheat, barley, and corn. In addition to dietary sources, proline can be synthesized from glutamate/glutamine, arginine, and ornithine. It can also be synthesized within enterocytes from degradation of small peptides.
Optimal range: 299.7 - 809.7 ng/mg CR
Proline is a nonessential amino acid. It contains a secondary α-imino group and is sometimes called an α-imino acid. Proline, and its metabolite hydroxyproline, constitute a third of the total amino acids found in collagen. Lysine, proline, hydroxyproline, and vitamin C are all important in the synthesis of collagen for skin, bones, tendons, and cartilage. Proline is abundant in meat, bone meal, poultry, salmon, wheat, barley, and corn. In addition to dietary sources, proline can be synthesized from glutamate/glutamine, arginine, and ornithine. It can also be synthesized within enterocytes from degradation of small peptides.
Optimal range: 1 - 50 qM/g creatinine
LEARN MOREOptimal range: 84.8 - 352.5 umol/L
Proline is a nonessential amino acid, which means that it is manufactured from other amino acids in the liver; it does not have to be obtained directly through the diet.
Proline is the precursor to hydroxyproline, which is a major amino acid found in the connective tissue of the body – collagen.
Optimal range: 11 - 57 Units
Proline is a nonessential amino acid. It contains a secondary α-imino group and is sometimes called an α-imino acid.
Proline, and its metabolite hydroxyproline, constitute a third of the total amino acids found in collagen. Lysine, proline, hydroxyproline, and vitamin C are all important in the synthesis of collagen for skin, bones, tendons, and cartilage.
Proline is abundant in meat, bone meal, poultry, salmon, wheat, barley, and corn.
Optimal range: 1 - 9 micromol/g creatinine
Proline is a nonessential amino acid. It contains a secondary α-imino group and is sometimes called an α-imino acid. Proline, and its metabolite hydroxyproline, constitute a third of the total amino acids found in collagen. Lysine, proline, hydroxyproline, and vitamin C are all important in the synthesis of collagen for skin, bones, tendons, and cartilage. Proline is abundant in meat, bone meal, poultry, salmon, wheat, barley, and corn. In addition to dietary sources, proline can be synthesized from glutamate/glutamine, arginine, and ornithine. It can also be synthesized within enterocytes from degradation of small peptides.
Optimal range: 0 - 2 mmol/mol creatinine
Proline is a nonessential amino acid. It contains a secondary α-imino group and is sometimes called an α-imino acid.
Proline, and its metabolite hydroxyproline, constitute a third of the total amino acids found in collagen. Lysine, proline, hydroxyproline, and vitamin C are all important in the synthesis of collagen for skin, bones, tendons, and cartilage.
Proline is abundant in meat, bone meal, poultry, salmon, wheat, barley, and corn.
Optimal range: 0 - 27.9 nmol/mg Creatinine
Collagen Catabolism: Collagen contains proline, hydroxyproline, and glycine.
→ Sarcopenia (low muscle mass) was associated with higher plasma proline.
→ Proline was significantly lower in esophageal cancer patients compared to the healthy controls.
→ Hydroxyproline and proline together constitute around 25% of residues and allow for stability and twisting of collagen.
→ Dietary intake increases levels of proline and hydroxyproline.
→ Proline and hydroxyproline both negatively correlated with a higher likelihood of anxiety, depression, and psychoses.
Optimal range: 117.2 - 411.9 nmol/ML
Proline is a nonessential amino acid. It contains a secondary α-imino group and is sometimes called an α-imino acid. Proline, and its metabolite hydroxyproline, constitute a third of the total amino acids found in collagen. Lysine, proline, hydroxyproline, and vitamin C are all important in the synthesis of collagen for skin, bones, tendons, and cartilage. Proline is abundant in meat, bone meal, poultry, salmon, wheat, barley, and corn. In addition to dietary sources, proline can be synthesized from glutamate/glutamine, arginine, and ornithine. It can also be synthesized within enterocytes from degradation of small peptides.
Optimal range: 99 - 363 µmol/L , 9.9 - 36.3 µmol/dL
Proline is a nonessential amino acid, which means that it is manufactured from other amino acids in the liver; it does not have to be obtained directly through the diet.
Proline is the precursor to hydroxyproline, which is a major amino acid found in the connective tissue of the body – collagen.
Optimal range: 1 - 13 micromol/g creatinine
Proline is a nonessential amino acid, which means that it is manufactured from other amino acids in the liver; it does not have to be obtained directly through the diet.
Proline is the precursor to hydroxyproline, which is a major amino acid found in the connective tissue of the body – collagen.
Optimal range: 19 - 83 ug/L
Procollagen I intact N-terminal propeptide (PINP) values should not be used as a screening test for osteoporosis in the general population. PINP is used to monitor bone formation and antiresorptive therapies. PINP should be measured prior to the start of therapy to determine a baseline value and again at 3 to 6 months after initiation of therapy. Therapeutic response is evaluated by comparing pre and post-treatment values.
Optimal range: 0 - 32 %
Propionate is among the most common short-chain fatty acids produced in the human gut in response to indigestible carbohydrates (fiber) in the diet.
Optimal range: 11 - 25 %
Propionate is among the most common short-chain fatty acids produced in the human gut in response to indigestible carbohydrates (fiber) in the diet.
Optimal range: 15.4 - 30.3 %
Propionate is among the most common short-chain fatty acids produced in the human gut in response to indigestible carbohydrates (fiber) in the diet.
Optimal range: 0 - 500 rpkm
Propionate is among the most common short-chain fatty acids produced in the human gut in response to indigestible carbohydrates (fiber) in the diet.
Optimal range: 0 - 29.3 %
Propionate is among the most common short-chain fatty acids produced in the human gut in response to indigestible carbohydrates (fiber) in the diet.
Optimal range: 6.86 - 16.91 Healthy Relative Abundance IQR (%)
Propionate is a SCFA that can be produced by gut bacteria through the fermentation of key fibers or the metabolism of lactate. Propionate supports a healthy immune system by encouraging regulatory T cell differentiation in gut associated lymphoid tissues (GALT), and it also promotes gluconeogenesis in the liver, supports insulin sensitivity, and improves gut hormone production. Propionate and butyrate both work together to support healthy inflammatory responses by inhibiting histone deacetylases (HDACs) in macrophages and dendritic cells.
Optimal range: 10 - 1000 Units
Propionibacterium is a genus capable of producing SCFAs, predominantly acetate and propionic acid.
The genus Propionibacterium consists of two principal groups, cutaneous and classical or dairy. Cutaneous species are predominant members of the microbial population of human skin and have also been isolated from the feces of humans and other vertebrate animals. They are often considered opportunistic organisms and have been occasionally associated with infections in humans.