The Hexagonal Phase Confirm test is a specific laboratory test used to detect lupus anticoagulant (LA), which is a type of antibody associated with antiphospholipid syndrome and other autoimmune disorders. The term "Hexagonal Phase" refers to a particular method of confirming the presence of LA. This test is part of a broader Lupus Anticoagulant Evaluation which may include various other tests to assess for the presence of these antibodies because they show a great deal of heterogeneity.

The Hexagonal Phase Phospholipid test detects lupus anticoagulants (LA), autoantibodies linked to clotting disorders and antiphospholipid syndrome (APS). Using a specific phase of phospholipids, it sensitively identifies LA, which disrupt normal clotting processes. A positive result suggests an increased risk of blood clots or complications like recurrent miscarriages, while a negative result typically rules out LA as a factor. This test, often performed alongside others like dRVVT, is crucial for diagnosing APS and guiding treatment to manage clotting risks. Abnormal results should be reviewed with a healthcare provider for further evaluation and management.

The Hexagonal Phospholipid Neutralization test is a laboratory test used to detect lupus anticoagulants, which are antibodies that can lead to blood clotting problems. It is highly sensitive but may require additional tests for confirmation in the clinical assessment of antiphospholipid syndrome and related disorders.

Urinary hexanoylglycine is a specific marker for the diagnosis of Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency. 

Urinary hexanoylglycine is a specific marker for the diagnosis of Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency. 

Anaplasmosis is a tick-borne infection that can sometimes be severe or fatal. Anaplasmosis is caused by the bacteria, Anaplasma phagocytophilum. It cannot be spread from person-to-person. You may develop anaplasmosis if you are bitten by an infected blacklegged tick.

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An "Indeterminate" result (where result falls in the "orange" reference range) on an HGA IFA - IgG test, suggests that the detected levels of IgG antibodies are neither clearly positive nor negative. This ambiguous result can occur in various scenarios, such as during the early stages of infection when antibody levels are rising, during the resolution phase of a past infection when antibody levels are declining, or due to cross-reactivity with antibodies from similar infections. It poses interpretation challenges and often necessitates further evaluation considering the clinical context, including symptoms and history of tick exposure. In some cases, repeat testing after a period may be required to monitor changes in antibody levels, thereby aiding in clarifying the diagnosis. This indeterminate result highlights the complexity of diagnosing anaplasmosis solely based on serological testing and underscores the need for a comprehensive clinical assessment.

The HGA (Human Granulocytic Anaplasmosis) IFA (Indirect Fluorescent Antibody) - IgM test on an Anaplasmosis panel is a crucial diagnostic tool for the detection of acute Human Granulocytic Anaplasmosis, a tick-borne disease caused by the bacterium Anaplasma phagocytophilum. This test specifically measures the presence of Immunoglobulin M (IgM) antibodies, which are the first type of antibody produced by the immune system in response to an infection. The presence of IgM antibodies specific to A. phagocytophilum indicates a recent or acute infection, as these antibodies typically become detectable within the first few weeks after exposure and generally peak within a month before gradually declining.

Hemoglobin A makes up about 95%-98% of Hb found in adults; it contains two alpha and two beta protein chains.

Hemoglobin A2 makes up about 2%-3% of Hb in adults; it has two alpha and two delta protein chains.

Hemoglobin C can cause a minor amount of hemolytic anemia.

Hemoglobin F (fetal hemoglobin) makes up to 1%-2% of Hb found in adults; it has two alpha and two gamma protein chains. This is the primary hemoglobin produced by the fetus during pregnancy; its production usually falls shortly after birth and reaches adult levels by 1-2 years.

Hemoglobin S, the primary hemoglobin in people with sickle cell disease that causes the RBC to become misshapen (sickle), decreasing the cell's survival.

The Hemoglobin Solubility test is used to help identify the presence of Hemoglobin S. The test may also detect sickling hemoglobins, and evaluate hemolytic anemia.