H. pylori, a gram-negative bacterium colonizes the gastrointestinal system, where is interferes with intestinal barrier functions, induces inflammatory responses and can contribute to autoimmunity. Mechanisms of autoimmunity include molecular mimicry, polyclonal activation, epitope spreading, bystander activation and super antigen release. H. pylori has been implicated in disorders of the thyroid, liver, joints and nervous system.
Helicobacter pylori
Helicobacter pylori
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