The Anti-Ro (SS-A) Antibody test is a critical diagnostic tool in the assessment of autoimmune diseases. This test detects antibodies against the Ro/SS-A antigen, a protein implicated in the development of certain autoimmune conditions. The presence of Anti-Ro (SS-A) antibodies is notably associated with Sjögren's syndrome, a disorder characterized by dry eyes and mouth, and systemic lupus erythematosus (SLE).
These antibodies are also found in patients with subacute cutaneous lupus and neonatal lupus, a rare condition affecting infants born to mothers with these antibodies. In Sjögren's syndrome, the detection of Anti-Ro (SS-A) antibodies is particularly significant, as it aids in diagnosing the disease, which can be challenging to identify due to its overlapping symptoms with other conditions. Additionally, these antibodies are relevant in pregnant women with autoimmune disorders, as they are linked to an increased risk of complications like congenital heart block in the fetus. The test results should always be interpreted alongside clinical symptoms and other laboratory findings, as Anti-Ro (SS-A) antibodies can sometimes be present in individuals without any autoimmune disease.
Anti-Ro (SS-A) Ab (RDL)
Every lab result you’ve ever had, charted and explained.
Healthmatters is a tracker for your lab results. Upload a report from any lab, any country — every marker charted and explained.
Start with my report →
All our content is backed by peer-reviewed studies, academic research, and trusted medical sources. We’re committed to accuracy and transparency — see our editorial policy for details.