Troponin proteins are released when the heart muscle has been damaged, such as occurs with a heart attack. The more damage there is to the heart, the greater the amount of troponin T and I there will be in the blood.
Cardiac troponin levels are normally so low they cannot be detected with most blood tests. Having normal troponin levels 12 hours after chest pain has started means a heart attack is unlikely.
A normal value range may vary slightly among different laboratories. Some labs use different measurements (for example, “high sensitivity troponin test”) or test different samples. Also, some labs have different cutoff points for “normal” and “probable myocardial infarction.” Talk to your provider about the meaning of your specific test results.
Even a slight increase in the troponin level will often mean there has been some damage to the heart. Very high levels of troponin are a sign that a heart attack has occurred.
Most patients who have had a heart attack have increased troponin levels within 6 hours. After 12 hours, almost everyone who has had a heart attack will have raised levels.
Troponin levels may remain high for 1 to 2 weeks after a heart attack.
Increased troponin levels may also be due to:
Increased troponin levels may also result from certain medical procedures such as:
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