Borrelia burgdorferi B31 reference strain (Borrelia burgdorferi sensu stricto) lysate of Borrelia burgdorferi contains many different antigens capable of evidencing cellular activity.

Borrelia burgdorferi is spirochete class bacterium. B. burgdorferi sensu stricto, B. burgdorferi sensu lato, B. burgdorferi afzelii and B. burgdorferi garinii spirochetes enter the human body through tick bites. Mixed with tick saliva, Borrelia travels through the circulation and enters different tissues. In some untreated cases, symptoms of pathogenic invasion have involved neurologic, cardiac, or joint disorders. Borrelia pathogenesis can break the blood-brain barrier, which allows invasion of the central nervous system, resulting in neuroborreliosis.

Borrelia burgdorferi sensu lato (B.b.s.l.) with the following subspecies:

- USA: Borrelia burgdorferi sensu stricto (B.b.s.s.), Borrelia andersonii, Borrelia americanum, B. carolinensis, B. bissettii, B. myamotoi

- Europe: Borrelia afzelii, Borrelia garinii, B. spielmanii, B. valaisiana, B. lusitaniae, B. bavariensis

- Asia: Borrelia japonica, B. rutdi, B. tanukii, B. sinica, B. yangtze

There are 3 stages of an infection:

1. Bull’s eye rash, summer-flu,

2. Recent infection of the organ system (peripheral nerve system, meningitis, encephalitis, joints, heart, eyes),

3. Chronic infection of the organ system (peripheral nerve system, central nerve system, joints, muscles, heart, eyes, ears, skin

Symptoms

(according “Symptoms and Associated Medical Conditions on the Sixteen-Point MSIDS Map” by Dr. Richard Horowitz, Hyde Park, New York, USA)

- Fatique, tiredness, unexplained fevers, sweats, chills or flushing, unexplained weight change, either loss or gain, unexplained hair loss, swollen glands, sore throat, testicular pain (men), pelvic pain (women), unexplained menstrual irregularity, unexplained milk production, breast pain, irritable bladder or bladder dysfunction, sexual dysfunction or loss of libido, upset stomach, change in bowel function (constipation or diarrhea), chest pain or rib soreness, shortness of breath, cough, heart palpitations, pulse skips, heart block, any history of a heart murmur or valve prolapse, joint pain or swelling, stiffness of joints, neck or back, muscle pain or cramps, twitching of the face or other muscles, headaches, neck cracks, neck stiffness, tingling numbness, burning or stabbing sensations, facial paralysis (Bell´s palsy), double, blurry or floaters of the eyes/vision, buzzing, ringing of the ears/hearing, ear pain, increased motion sickness, vertigo, light-headedness, wooziness, poor balance, difficulty walking, tremor, confusion, difficulty thinking, difficulty with concentration or reading, forgetfulness, poor short-term memory, desorientation: getting lost, going to wrong places, difficulty with speech or writing, mood swings, irritability, depression, disturbed sleep: too much or too little sleep or early awakening, disturbed sleep: too much or too little sleep or early awakening (continued), exaggerated symptoms or worse hangover from alcohol.