58 KD (IGG) Band

Optimal Result: 0 - 0.001 Units.

Two types of antibodies are detected in the Western blot test.

This particular marker is called 58 KD (IGG) Band and hence is a IgG antibody marker. IgG antibodies are a sign of an older infection. In contrast, IgM antibodies reflect a relatively recent infection. 

IgM antibodies usually disappear after eight weeks post-exposure. 
IgG remains in the serum for a very long time. 

In the Western blot test there are three bands for IgM and 10 bands for IgG.

Here is the important part:

- You need to have 2 out of 3 for the positive IgM result

- Or you need to have 5 out of 10 for the positive IgG result. 

Either one confirms the diagnosis if symptoms are present.

What does it mean if your 58 KD (IGG) Band result is too high?

Two types of antibodies are detected in the Western blot test.

This particular marker is called 58 KD (IGG) Band and hence is a IgG antibody marker. IgG antibodies are a sign of an older infection. In contrast, IgM antibodies reflect a relatively recent infection. 

IgM antibodies usually disappear after eight weeks post-exposure. 
IgG remains in the serum for a very long time. 

In the Western blot test there are three bands for IgM and 10 bands for IgG.

Here is the important part:

- You need to have 2 out of 3 for the positive IgM result

- Or you need to have 5 out of 10 for the positive IgG result. 

Either one confirms the diagnosis.

Here is the 2nd important part when it comes to a diagnosis:

If a person doesn't have signs or symptoms of Lyme disease, then the person does not have Lyme disease as the definition of disease requires symptoms.

What could some of those symptoms be?

What are the symptoms of Lyme disease?

Lyme disease symptoms are wide-ranging, with more than a hundred different symptoms recorded. Symptoms can also change over time, as the bacteria spreads throughout the body. To make things more confusing, Lyme disease symptoms will also vary from patient-to-patient. Lyme disease can mimic hundreds of other conditions since its symptoms mirror many medical problems such as multiple sclerosis, arthritis, chronic fatigue syndrome or lupus, and is sometimes known as “The Great Imitator” because of this. 

Symptoms can play a key role in diagnosing Lyme disease. Due to the lack of an accurate diagnostic test, many patients are diagnosed based on a combination symptoms and diagnostic testing. This makes it extremely important for patients to keep track of all the symptoms they experience, to share with their healthcare provider. Lyme disease symptoms can vary based on stage of the disease (early, late, post-treatment, or chronic) and if other tick-borne infections are present and can change over time.

Symptoms in acute Lyme disease:

Acute Lyme disease (aka: early localized LD) occurs days to weeks after the initial tick bite and infection, in which the bacteria have not yet spread from the site of infection in the skin.

The most common symptoms in acute (aka: early localized) Lyme disease are the ones people are most familiar with. Because they are symptoms often shared with other illnesses, however, it’s important to recognize that they could mean Lyme and you should see a Lyme-treating physician right away.

- Erythema migrans rash or EM rash. This rash begins at the site of the tick bite about a week after the bite, and gradually expands.

Note: The center of the rash may clear, giving the rash the appearance of a “bulls-eye.” Rashes may take on many different shapes and not all rashes will have a bulls-eye appearance. There can be multiple rashes on the body. While a rash is characteristic of Lyme disease, many people will not develop a rash at all.

- Fever

- Fatigue

- Aches

- Chills

- Swollen lymph nodes

- Other flu-like symptoms

Symptoms in early disseminated Lyme disease:

Early disseminated Lyme disease occurs days to months after infection, in which the bacteria have begun to spread. There is a wide range of possible symptoms at this stage, including:

- Severe headaches and neck stiffness

- Arthritis, especially in the knees or other large joints

- Muscle aches and pains

- Heart palpitations or shortness of breath (Lyme carditis)

- Facial paralysis on one or both sides (also known as Bell’s palsy)

- Numbness or tingling in the hands or feet

- Extreme fatigue

Symptoms in late stage Lyme disease:

Late stage Lyme disease, which can include post-treatment, chronic, and neurological, occurs months to years after infection, in which the bacteria have spread throughout the body.

The symptoms of late disseminated disease are similar to those of early disseminated disease, but may be more extensive, more severe, and longer lasting. Late symptoms may also include:

- neurologic features including vertigo or dizziness,

- difficulty sleeping

- mental fogginess

- difficulty following conversations

- difficulty processing information

A blood test may be positive for several reasons: 

First, the positive test may indicate that the person was infected previously by the agent of Lyme disease and the immune system mounted a successful attack which resulted in the long-term production of antibodies against the agent of Lyme disease. That's why tests can stay positive for months to years, even when active infection is no longer present. We expect, however, that over time the ELISA titer should decrease in magnitude.

Second, a positive test may also indicate that there is a small amount of persistent infection that is continuing to partially stimulate the immune system. The residual organism may not be biologically active; i.e., it might be in a latent or dormant state and thus not causing any disease symptoms. In this case, the ELISA titer may stay elevated for long periods without a gradual decline.

Third, a positive test may be a false positive, especially if the positive test is only an ELISA. It is well known for example that concurrent viral infections (such as Epstein-Barr) may result in a false positive Lyme ELISA. If the positive test is an IgG Western blot or a C6 Lyme ELISA, it is very unlikely that either test would be falsely positive.

Fourth, a positive test may indicate that you did have some of the signs or symptoms of Lyme disease in the past but didn't recognize the problem as Lyme disease. You may have then been treated with antibiotics for another reason and this may have led to a resolution of the Lyme disease without your awareness of ever having had Lyme disease.

Frequently asked questions

Unlock Your Health Journey with Healthmatters.io! Ever wished for a one-stop digital health haven for all your lab tests? Look no further! Healthmatters.io is your personalized health dashboard, bringing together test reports from any lab. Say goodbye to scattered results—organize and centralize your lab data effortlessly. Dive into the details of each biomarker and gain insights into the meaning behind your medical test data.

Join the community of thousands who've transformed the way they understand their lab results. Experience the joy of having all your lab data neatly organized, regardless of where or when the tests were done.

For our professional users, Healthmatters.io is a game-changer. Revel in the intuitive tools that not only streamline analysis but also save valuable time when delving into your client's lab report history. It's not just a dashboard; it's your gateway to a smarter, more informed health journey!

Healthmatters.io personal account provides in-depth research on 4000+ biomarkers, including information and suggestions for test panels such as, but not limited to:

  • The GI Effects® Comprehensive Stool Profile,
  • GI-MAP,
  • The NutrEval FMV®,
  • The ION Profile,
  • Amino Acids Profile,
  • Dried Urine Test for Comprehensive Hormones (DUTCH),
  • Organic Acids Test,
  • Organix Comprehensive Profile,
  • Toxic Metals,
  • Complete Blood Count (CBC),
  • Metabolic panel,
  • Thyroid panel,
  • Lipid Panel,
  • Urinalysis,
  • And many, many more.

You can combine all test reports inside your Healthmatters account and keep them in one place. It gives you an excellent overview of all your health data. Once you retest, you can add new results and compare them.

If you are still determining whether Healthmatters support your lab results, the rule is that if you can test it, you can upload it to Healthmatters.

While we do talk about popular labs, we welcome reports from lots of other places too. It's as simple as this: if you can get a test done, you can upload it to Healthmatters. We can interpret results from any lab out there. If laboratories can analyze it, we can interpret it.

Still on the hunt for a specific biomarker? Just tell us, and we'll add it to our database. Anything from blood, urine, saliva, or stool can be uploaded, understood, and tracked with your Healthmatters account!

There are two ways to add your test reports to your healthmatters.io account. One option is to input the data using the data entry forms. The other method is to utilize our "Data entry service."

Our data entry forms offer an easy, fast, and free way for you to input the reports yourself. Self-entry allows you to add an unlimited number of reports at no cost. We make the self-entry process user-friendly, providing dozens of templates that pre-populate the most popular laboratory panels and offering instant feedback on entered values.

For those who prefer assistance, we offer a "Data entry service" to help you input your data. Simply attach an image or file of your lab test results, and a qualified team member from our data entry team will add the results for you. We support various file types, including PDFs, JPGs, or Excel. This service is particularly useful if you have many reports to upload or if you're too busy to handle the data entry yourself.

Our special data entry service makes it easy to add your results to your private dashboard. Just attach an image or a file of your lab test results, and our skilled data entry team will do the work for you. It's all done by humans, ensuring that your data is entered accurately and with personal care for each client.

Depending on your account, the data entry service can be included for free or come at an additional cost of $15 per report.

For users on the Complete monthly plan, the first report is entered free of charge, and each additional report incurs a fee of $15.

Unlimited account holders enjoy the entry of ten reports without charge. Subsequent reports are subject to a $15 fee per report.

Additionally, users on the Complete plan can upgrade to a yearly subscription from the account settings. The annual subscription includes a data entry service for five reports.

The Unlimited plan is a one-time purchase for $250, and it covers your account for a lifetime with no additional payments.

For the Complete plan, the cost is $15 per month. You have the flexibility to cancel it anytime through your account settings, ensuring no further payments. To avoid charges, remember to cancel at least a day before the renewal date. Once canceled, the subscription remains active until the end of the current billing cycle.

Additionally, you can upgrade to the yearly Advanced plan from within your account. The annual cost is $79, and it comes with a data entry service for five reports.

You can always upgrade to a lifetime version with a prorated price from a monthly or yearly subscription.

Simply log in and navigate to your account settings to cancel your subscription. Scroll down to locate the 'Cancel' button at the bottom of the page. Ensure you cancel at least one day before the renewal date to prevent any charges. Once cancellation is requested, the subscription remains active until the conclusion of the current billing cycle.

Unlocking the insights from your lab tests has never been this intuitive! We've crafted multiple ways for you to navigate your data, whether you're glancing at a single report or delving into a treasure trove of testing data.

1. Graph View:

Dive into a visual journey with our biomarker graphs, showcasing over 40 data points. Combining years of results unveils trends, empowering you to make informed decisions. Our visualization tools make it a breeze to compare and understand changes over time, even if your results are from different labs. A search function and filters simplify the exploration of extensive data, allowing you to focus on what needs attention.

2. All Tests View

Get a quick grasp of your test reports in minutes! Explore neatly organized reports on a timeline, highlighting crucial details like dates, critical results, and lab/panel names. Each report opens up to reveal in-depth descriptions and additional recommendations for each biomarker. The history of previous results is just a click away, and you can download a comprehensive report for deeper insights. Color-coded and user-friendly, it's designed for easy reading, understanding, and navigation.

3. Table View:

For a holistic view of all biomarkers side by side, our table view is your go-to. Results are neatly displayed in a categorized and dated table, ideal for those with an extensive test history. Utilize sorting, filters, and color-coding to enhance your analysis and gain extra insights.

Experience the power of clear, organized data visualization with Healthmatters.io — your key to understanding and taking charge of your health journey!

Yes, you can download information from your account. We can compile your labs into a CSV file. To download all your labs, you can go to Account Settings, and at the bottom of the page, you will find a link to download your information.

Yes, you can print your report. To do so, navigate to "All tests" and open the report you wish to print. You'll find a print button in the right corner of the report. Click on it, and your browser's print window will open. If you prefer to print in a bigger typeface, adjust the scale using the print window settings.

A personal account is all about keeping your own lab test results in check. It's just for you and your personal use.

The professional or business account is designed for health professionals who wish to track and organize their clients' laboratory results.

Use promo code to save 10% off any plan.

We implement proven measures to keep your data safe.

At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.