Serotonin is a neurotransmitter associated with happiness and contributes to our overall sense of well-being. If we experience anxiety, it could indicate an imbalance in serotonin levels. Such imbalances may manifest in various ways, such as sleep disturbances, digestive problems, and intense cravings, to name a few. Due to its role in regulating several bodily processes, testing for serotonin levels can help identify imbalances. Correcting low or high levels of serotonin can be achieved through dietary and lifestyle changes.
Serotonin's functions:
Serotonin is produced mainly in the gastrointestinal tract and central nervous system and is considered an inhibitory neurotransmitter, similar to GABA. Its inhibitory properties help to balance the excitatory effects of other neurotransmitters in the body. This balancing act is crucial for mood and sleep regulation, memory, pain management, and various other biological functions. Maintaining adequate levels of serotonin is essential for regulating mood, which can result in reduced anxiety, increased happiness, better focus, and a sense of calm. Moreover, serotonin also plays a vital role in regulating several other physiological processes, such as:
How is Serotonin made in the body?
Serotonin, like all neurotransmitters, is derived from an amino acid. It is the only neurotransmitter produced from tryptophan and is the end product of the metabolism of tryptophan to 5-hydroxytryptophan (5-HTP). Serotonin is produced in both the central nervous system and the GI tract. Nearly 90% of serotonin originates in the enterochromaffin cells of the small intestine. Platelet serotonin also originates in the small intestine. The remaining serotonin is produced in the brain. 1-3
What happens when you have a Serotonin imbalance?
Imbalanced serotonin levels are associated with a number of health concerns that impact quality of life. For example:
How does Serotonin interact with other hormones and Neurotransmitters?
Serotonin works in concert with other hormones and neurotransmitters. Estrogen, testosterone, dehydroepiandrosterone (DHEA), and thyroid hormone enhance serotonin activity. On the other hand, imbalances of cortisol as well as high insulin inhibit serotonin action. Imbalanced serotonin could also be a red flag for imbalanced melatonin levels. Optimized serotonin levels are known to promote healthy thyroid function and activity of the hypothalamus.
Serotonin works together with dopamine to maintain chemical balance in the CNS. They often produce opposite effects in the body to help maintain balance. For example:
How does Serotonin become imbalanced?
A number of factors can disrupt serotonin levels or associated hormones or neurotransmitters. These factors include:
How can we naturally support Serotonin?
It is possible to encourage healthy levels of serotonin through lifestyle measures, including:
References:
Keeping track of your medical data and laboratory results while understanding what they mean empowers positive health outcomes.
Keeping track of your medical data and lab results while understanding what they mean empowers positive health outcomes.
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Serotonin syndrome, or the condition of having too much serotonin, usually happens when taking one or more medications that increase serotonin levels. Serotonin syndrome can be life-threatening and should be addressed immediately.
Symptoms of too much Serotonin:
A rare type of cancer called a carcinoid tumor can produce high levels of serotonin in the body and may cause skin flushing, diarrhea, difficulty breathing, rapid heartbeat, or skin lesions on the face.
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