Bartonella genus (IgM)


Reference range:

Bartonellosis, a group of infectious diseases caused by bacteria of the Bartonella genus, can be diagnosed using serological panels that include the Bartonella genus (IgM) marker test. This test is designed to detect Immunoglobulin M (IgM) antibodies in the blood, which are produced by the immune system as an early response to a Bartonella infection. Bartonella species, including Bartonella henselae and Bartonella quintana, are known to cause diseases such as cat scratch disease, trench fever, and bacillary angiomatosis.

The presence of IgM antibodies specific to Bartonella indicates a recent or acute infection, as these antibodies are typically produced within a week or two of infection and can persist for several months. The test employs an indirect immunofluorescence assay (IFA) or enzyme-linked immunosorbent assay (ELISA) methodology, where a patient's serum is exposed to antigens derived from Bartonella species. If specific IgM antibodies are present, they bind to these antigens, and this binding can be visualized and quantified through secondary antibodies labeled with a detectable marker. However, the interpretation of this test must be approached with caution. Cross-reactivity with antibodies produced against other pathogens, the persistence of IgM antibodies even after the resolution of infection, and the potential for false positives, particularly in populations with endemic exposure to Bartonella, can complicate the clinical picture.

Therefore, the results of the Bartonella genus (IgM) test should be considered alongside clinical symptoms, patient history, and possibly other diagnostic methods, such as PCR or culture, to accurately diagnose bartonellosis. This test is a valuable tool in the early diagnosis of Bartonella infections, but its results require careful interpretation in the broader context of the patient's clinical presentation.

10 000+ happy customers
100% satisfaction
★ ★ ★ ★ ★ customer support

Trust us to examine your lab results, guiding you towards improved health.

Use promo code to save 10% off any plan.

We implement proven measures to keep your data safe.

At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.