B. duncani IFA - IgM

Optimal Result: 0 - 20 titer.

Babesiosis, a tick-borne illness caused by Babesia parasites, is commonly diagnosed using serological testing, where the B. duncani IFA (Indirect Fluorescent Antibody) IgM test plays a crucial role. This test specifically detects IgM antibodies against B. duncani, a Babesia species predominantly found in the western United States. IgM antibodies are among the first antibodies produced by the immune system when it encounters a pathogen. The presence of these antibodies is indicative of a recent or acute infection. The B. duncani IFA - IgM test utilizes the principle of indirect fluorescence, where patient serum is incubated with antigen-coated slides containing B. duncani organisms. If IgM antibodies specific to B. duncani are present, they bind to the antigens. This binding is then visualized using a fluorescently-labeled anti-human IgM secondary antibody. The intensity of the fluorescence, observed under a specialized microscope, correlates with the antibody concentration, providing qualitative and semi-quantitative data. This test is highly specific, but cross-reactivity with other Babesia species or closely related parasites can occur, leading to potential false positives. Additionally, as IgM antibodies decline over time post-infection, the test is most effective for identifying recent infections and may not be reliable for detecting chronic or past infections. Therefore, the B. duncani IFA - IgM test is a valuable tool for the early diagnosis of Babesiosis, particularly in geographical areas where B. duncani is prevalent, but it should be interpreted in the context of clinical symptoms and other diagnostic findings.

What does it mean if your B. duncani IFA - IgM result is too high?

Elevated levels of IgM antibodies detected by the B. duncani IFA - IgM test in a Babesiosis panel generally indicate a recent or acute infection with the Babesia duncani parasite. IgM is an early response antibody, meaning its increased presence typically suggests that the body has recently encountered the pathogen and the immune system is actively responding. However, it's important to note that elevated IgM levels alone are not definitive proof of an active infection; they should be interpreted alongside clinical symptoms and possibly other diagnostic tests, as false positives can occur due to cross-reactivity with similar pathogens.


Babesiosis, particularly when caused by the Babesia parasite like B. duncani, can manifest in a spectrum of symptoms which can vary greatly in their severity; some individuals may even remain asymptomatic. Common symptoms often resemble those of a mild to severe flu and include sudden spikes in temperature accompanied by chills, a general feeling of tiredness and lack of energy, persistent and sometimes severe headaches, excessive sweating especially during fever episodes, generalized body aches and pains, and pain in the joints. Gastrointestinal symptoms like nausea, vomiting, and a decrease in appetite are also frequently reported, alongside darkened urine due to the breakdown of red blood cells, a condition known as hemoglobinuria. In severe cases, particularly in individuals who are immunocompromised, elderly, or without a functioning spleen, babesiosis can escalate to more serious complications including hemolytic anemia, which is the destruction of red blood cells leading to anemia, jaundice marked by yellowing of the skin and eyes due to increased bilirubin, respiratory symptoms such as shortness of breath or cough due to low oxygen levels in the blood, and, in rare instances, impaired kidney function leading to renal failure. The severity and combination of these symptoms can vary widely from person to person, making it important for those who suspect they have been exposed to ticks in areas where Babesia is endemic and are experiencing such symptoms to seek medical attention promptly for diagnosis and treatment, which is crucial for preventing more severe outcomes and complications.

Treatment options:

In terms of treatment, Babesiosis, especially caused by B. duncani, is typically treated with a combination of antimicrobial and antiparasitic drugs. The most common regimen includes a combination of atovaquone and azithromycin. In more severe cases, or when patients are intolerant to these medications, a combination of clindamycin and quinine may be used. The duration and specific choice of treatment depend on the severity of the infection, the patient's overall health, and potential drug tolerances or allergies. Supportive care is also crucial, particularly in managing symptoms and any complications that may arise. It's important for patients to have ongoing medical supervision during treatment, as Babesiosis can be a serious condition, especially in individuals with weakened immune systems, the elderly, or those without a spleen. Additionally, preventative measures against tick bites are recommended in areas where Babesia is endemic, as this is the primary mode of transmission for the disease.

Frequently asked questions

Unlock Your Health Journey with Healthmatters.io! Ever wished for a one-stop digital health haven for all your lab tests? Look no further! Healthmatters.io is your personalized health dashboard, bringing together test reports from any lab. Say goodbye to scattered results—organize and centralize your lab data effortlessly. Dive into the details of each biomarker and gain insights into the meaning behind your medical test data.

Join the community of thousands who've transformed the way they understand their lab results. Experience the joy of having all your lab data neatly organized, regardless of where or when the tests were done.

For our professional users, Healthmatters.io is a game-changer. Revel in the intuitive tools that not only streamline analysis but also save valuable time when delving into your client's lab report history. It's not just a dashboard; it's your gateway to a smarter, more informed health journey!

Healthmatters.io personal account provides in-depth research on 4000+ biomarkers, including information and suggestions for test panels such as, but not limited to:

  • The GI Effects® Comprehensive Stool Profile,
  • GI-MAP,
  • The NutrEval FMV®,
  • The ION Profile,
  • Amino Acids Profile,
  • Dried Urine Test for Comprehensive Hormones (DUTCH),
  • Organic Acids Test,
  • Organix Comprehensive Profile,
  • Toxic Metals,
  • Complete Blood Count (CBC),
  • Metabolic panel,
  • Thyroid panel,
  • Lipid Panel,
  • Urinalysis,
  • And many, many more.

You can combine all test reports inside your Healthmatters account and keep them in one place. It gives you an excellent overview of all your health data. Once you retest, you can add new results and compare them.

If you are still determining whether Healthmatters support your lab results, the rule is that if you can test it, you can upload it to Healthmatters.

While we do talk about popular labs, we welcome reports from lots of other places too. It's as simple as this: if you can get a test done, you can upload it to Healthmatters. We can interpret results from any lab out there. If laboratories can analyze it, we can interpret it.

Still on the hunt for a specific biomarker? Just tell us, and we'll add it to our database. Anything from blood, urine, saliva, or stool can be uploaded, understood, and tracked with your Healthmatters account!

There are two ways to add your test reports to your healthmatters.io account. One option is to input the data using the data entry forms. The other method is to utilize our "Data entry service."

Our data entry forms offer an easy, fast, and free way for you to input the reports yourself. Self-entry allows you to add an unlimited number of reports at no cost. We make the self-entry process user-friendly, providing dozens of templates that pre-populate the most popular laboratory panels and offering instant feedback on entered values.

For those who prefer assistance, we offer a "Data entry service" to help you input your data. Simply attach an image or file of your lab test results, and a qualified team member from our data entry team will add the results for you. We support various file types, including PDFs, JPGs, or Excel. This service is particularly useful if you have many reports to upload or if you're too busy to handle the data entry yourself.

Our special data entry service makes it easy to add your results to your private dashboard. Just attach an image or a file of your lab test results, and our skilled data entry team will do the work for you. It's all done by humans, ensuring that your data is entered accurately and with personal care for each client.

Depending on your account, the data entry service can be included for free or come at an additional cost of $15 per report.

For users on the Complete monthly plan, the first report is entered free of charge, and each additional report incurs a fee of $15.

Unlimited account holders enjoy the entry of ten reports without charge. Subsequent reports are subject to a $15 fee per report.

Additionally, users on the Complete plan can upgrade to a yearly subscription from the account settings. The annual subscription includes a data entry service for five reports.

The Unlimited plan is a one-time purchase for $250, and it covers your account for a lifetime with no additional payments.

For the Complete plan, the cost is $15 per month. You have the flexibility to cancel it anytime through your account settings, ensuring no further payments. To avoid charges, remember to cancel at least a day before the renewal date. Once canceled, the subscription remains active until the end of the current billing cycle.

Additionally, you can upgrade to the yearly Advanced plan from within your account. The annual cost is $79, and it comes with a data entry service for five reports.

You can always upgrade to a lifetime version with a prorated price from a monthly or yearly subscription.

Simply log in and navigate to your account settings to cancel your subscription. Scroll down to locate the 'Cancel' button at the bottom of the page. Ensure you cancel at least one day before the renewal date to prevent any charges. Once cancellation is requested, the subscription remains active until the conclusion of the current billing cycle.

Unlocking the insights from your lab tests has never been this intuitive! We've crafted multiple ways for you to navigate your data, whether you're glancing at a single report or delving into a treasure trove of testing data.

1. Graph View:

Dive into a visual journey with our biomarker graphs, showcasing over 40 data points. Combining years of results unveils trends, empowering you to make informed decisions. Our visualization tools make it a breeze to compare and understand changes over time, even if your results are from different labs. A search function and filters simplify the exploration of extensive data, allowing you to focus on what needs attention.

2. All Tests View

Get a quick grasp of your test reports in minutes! Explore neatly organized reports on a timeline, highlighting crucial details like dates, critical results, and lab/panel names. Each report opens up to reveal in-depth descriptions and additional recommendations for each biomarker. The history of previous results is just a click away, and you can download a comprehensive report for deeper insights. Color-coded and user-friendly, it's designed for easy reading, understanding, and navigation.

3. Table View:

For a holistic view of all biomarkers side by side, our table view is your go-to. Results are neatly displayed in a categorized and dated table, ideal for those with an extensive test history. Utilize sorting, filters, and color-coding to enhance your analysis and gain extra insights.

Experience the power of clear, organized data visualization with Healthmatters.io — your key to understanding and taking charge of your health journey!

Yes, you can download information from your account. We can compile your labs into a CSV file. To download all your labs, you can go to Account Settings, and at the bottom of the page, you will find a link to download your information.

Yes, you can print your report. To do so, navigate to "All tests" and open the report you wish to print. You'll find a print button in the right corner of the report. Click on it, and your browser's print window will open. If you prefer to print in a bigger typeface, adjust the scale using the print window settings.

A personal account is all about keeping your own lab test results in check. It's just for you and your personal use.

The professional or business account is designed for health professionals who wish to track and organize their clients' laboratory results.

Use promo code to save 10% off any plan.

We implement proven measures to keep your data safe.

At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.