The Lyme Immunoflourescence Assay (IFA) detects antibodies (IgG IgM, IgA) against B. burgdorferi in a patient's serum. Therefore, it is useful as a screening test at all stages of the disease.
IgM-specific antibodies are usually high during the early (or active) stage of the disease; and in some patients IgM may persist for a long time. Antibody levels tends to rise above background levels within 2-3 weeks after an infection. IgG appears later in the disease, but may remain present in low levels long after the disease is cured.
Borrelia burgdorferi is a pathogenic spirochete responsible for Lyme disease via a tick vector. This spirochete causes a characteristic annular rash, arthritis, carditis, and in late stages, encephalopathy.
References:
Tatum R, Pearson-Shaver AL. Borrelia Burgdorferi. [Updated 2022 Jul 18]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK532894/
Every lab result you’ve ever had, charted and explained.
Healthmatters is a tracker for your lab results. Upload a report from any lab, any country — every marker charted and explained.
Start with my report →All our content is backed by peer-reviewed studies, academic research, and trusted medical sources. We’re committed to accuracy and transparency — see our editorial policy for details.