Vitamin C has a major function of being an antioxidant. It boosts immunity through increasing white blood cells, in addition to supporting regeneration of vitamin E. Vitamin C can also reduce atherosclerosis, stroke and high blood pressure, and inflammation. Because of its role in the generation of connective tissue, it is necessary for optimal collagen production. Vitamin C is also an important component of l-carnitine, which is necessary for breakdown of fats into energy.
Food Sources:
Food sources of vitamin C include: oysters, tropical fruits such as guava, papaya, pineapple, oranges, kiwi, and cantaloupe; leafy greens such as kale and spinach; cruciferous vegetables such as broccoli, brussel sprouts, cauliflower, and cabbage; berries, such as strawberries, raspberries, blueberries, blackberries, bell peppers, and amaranth.
Supplement Options:
- The RDA for vitamin C is 75 mg/day for women and 90 mg/day for men. 120 mg/day is recommended during pregnancy and lactation.
- The half-life of vitamin C in circulation after supplementation is about 30 minutes, therefore, large singular doses of vitamin C may not be as therapeutic as smaller, more frequent doses of vitamin C.
- In addition to taking supplemental vitamin C, α-Lipoic acid helps restore vitamin C levels when depleted.
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Correlation between serum and WBC ("Cellular") levels:
Serum levels normal/excess and...
WBC - deficient:
Short term status of micronutrients is optiomal, but cellular absorption may be a problem.
Possible interventions:
- Increase dietary intake of nutrient
- increase supplementation dosage
- consider status of synergistic nutrients for cellular absorption
- consider levels of oxidative stress on nutrient depletion
- consider follow up testing to identify the source of malabsorption
How it gets depleted:
Vitamin C is most commonly depleted in the absence of sufficient dietary intake. Vitamin C levels can be depleted during times of severe oxidative stress.
Clinical Manifestations of Depletion:
- Low levels of vitamin C have been associated with reduced bone density.
- Signs of deficiency include: bleeding gums, easy bruising, anemia, fatigue, weakness and joint pain. These symptoms are the result of weakened or deficient connective tissues throughout the body.
- Severe cases of vitamin C deficiency are called scurvy.
--------------------------------------------
Correlation between serum and WBC ("Cellular") levels:
Serum levels deficient and...
WBC - normal:
Long term nutrient status is optiomal, but short term needs improvement.
Possible interventions:
- increase dietary intake of nutrient
- increase supplementation dosage
- medications may have an effect on depletion
WBC - deficient:
Short term and long term status of micronutrients is not optimal, suggesting low dietary intake and both intestinal and cellular malabsorption as possible causes.
Possible interventions:
- Increase dietary intake of nutrient
- increase supplementation dosage
- medications may have an effect on depletion
- consider follow up testing to identify the source of malabsorption
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AA (RBC), AA/EPA (RBC), Arginine (Serum), Asparagine (Serum), Asparagine (WBC), Calcium (Serum), Calcium (WBC), Carnitine (Serum), Carnitine (WBC), Choline (Serum), Choline (WBC), Chromium (Serum), Citrulline (Serum), Coenzyme Q10 (Serum), Coenzyme Q10 (WBC), Copper (Serum), Copper (WBC), Cysteine (Serum), Cysteine (WBC), DHA (RBC), DPA (RBC), EPA (RBC), Epstein Barr Virus EBNA1 (IgG), Epstein Barr Virus p18 (IgG), Epstein Barr Virus VCA gp125 (IgG), Folate (RBC), Folate (Serum), Glutamine (Serum), Glutamine (WBC), Glutathione (WBC), Inositol (Serum), Inositol (WBC), Iron (RBC), Iron (Serum), Isoleucine (Serum), LA (RBC), Leucine (Serum), Lymphocyte Count, Magnesium (RBC), Magnesium (Serum), Manganese (Serum), Manganese (WBC), MMA (Serum), Neutrophil Count, Omega-3 Index, Omega-3 Index (RBC), Potassium (Serum), Selenium (Serum), Selenium (WBC), Serine (Serum), Serine (WBC), Sodium (Serum), Streptococcal A (IgG), Total Omega-3 (RBC), Total Omega-6 (RBC), Valine (Serum), Vitamin A (Serum), Vitamin A (WBC), Vitamin B1 (Serum), Vitamin B1 (WBC), Vitamin B12 (Serum), Vitamin B12 (WBC), Vitamin B2 (Serum), Vitamin B2 (WBC), Vitamin B3 (Serum), Vitamin B3 (WBC), Vitamin B5 (Serum), Vitamin B5 (WBC), Vitamin B6 (Serum), Vitamin B6 (WBC), Vitamin C (Serum), Vitamin C (WBC), Vitamin D, 25-OH (Serum), Vitamin D3 (Serum), Vitamin D3 (WBC), Vitamin E (Serum), Vitamin E (WBC), Vitamin K1 (Serum), Vitamin K1 (WBC), Vitamin K2 (Serum), Vitamin K2 (WBC), WBC, Zinc (Serum), Zinc (WBC)