Kidney Health

Uric Acid

Optimal Result: 3.8 - 8.4 mg/dL, 226.02 - 499.63 µmol/L, or 0.23 - 0.50 mmol/L.

Therapeutic target for gout patients: <6.0 mg/dL

The blood uric acid test measures the amount of uric acid in a blood sample. Uric acid is produced from the breakdown of your body’s cells and from the foods you eat. Most of the uric acid is filtered by the kidneys and passes out of the body in urine, and a small amount passes out of the body in stool. If too much uric acid is being produced or if the kidneys are not able to remove it from the blood normally, then the level of uric acid in the blood increases. High levels of uric acid can cause solid crystals to form within joints. This causes a painful condition called gout. If gout remains untreated, these uric acid crystals can build up in the joints and nearby tissues, forming hard lumpy deposits called tophi. High levels of uric acid may also cause kidney stones or kidney failure. 

Normal Ranges:

Patient Specification

Normal Ranges in mg/dL

Normal Ranges in mcmol/L

Men

3.4-7.0

265-663

Women

2.4-6.0

143-357

Children

2.0-5.5

119-327

What does it mean if your Uric Acid result is too low?

Decreased uric acid levels are associated with detoxification issues, molybdenum deficiency, B12/folate anemia, and copper deficiency.

The typical focus of uric acid measurement is to assess the risk for gout, renal failure, and leukemia. However, this marker is also a strong indicator of potential inflammation and metabolic disturbance in the body.

Low levels of uric acid in the blood are seen much less commonly than high levels and are seldom considered cause for concern. Although low values can be associated with some kinds of liver or kidney diseases, these conditions are typically identified by other tests and symptoms and not by an isolated low uric acid result.

What does it mean if your Uric Acid result is too high?

Higher than normal uric acid levels in the blood, called hyperuricemia, can be caused by over-production of uric acid in the body or the inability of the kidneys to adequately remove enough uric acid from the body. Over-production of uric acid can be caused by:

- Metastatic cancer

- Multiple myeloma

- Certain leukemias

- Cancer chemotherapy

Failure to remove enough uric acid can be caused by:

- Chronic renal disease

- Acidosis

- Toxemia of pregnancy

- Alcoholism

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