This test estimates your recent uranium exposure by measuring how much uranium your body is eliminating in urine, adjusted for urine concentration (creatinine-corrected). Urine is the primary biomarker of uranium intake because most absorbed, soluble uranium is cleared through the kidneys; a smaller fraction is retained longer in bone and soft tissues. As a result, elevated urine values generally reflect exposure within the past days to weeks, not lifetime body stores.
Uranium’s health effects are driven mainly by its chemical (heavy-metal) toxicity, not its radioactivity, at environmental and most occupational levels. The kidney—especially the proximal tubule—is the most sensitive target, so clinicians watch for signs of tubular stress or injury when urine uranium is high. Experimental and epidemiologic studies also show oxidative stress and DNA damage/chromosomal aberrations at higher or prolonged exposures; however, outside of kidney effects, findings in humans are mixed, so results must be interpreted in context.
At or below 0.04 µg/g creatinine: Consistent with the lab’s reference population and near U.S. population background (NHANES 95th percentile ≈ 0.04 µg/g).
Above 0.04 µg/g creatinine: Indicates higher-than-expected recent exposure. A single result cannot precisely date exposure or quantify total body burden; trend data and exposure history are key.
Drinking water from uranium-rich aquifers (private wells in granitic/volcanic regions); public water exceeding the U.S. EPA MCL = 30 µg/L is uncommon but actionable.
Food and beverages prepared with high-uranium water; background levels in most foods are low.
Inhalation of dust/fumes in mining, milling, ore processing, refractory ceramics, or military/industrial settings. Dermal uptake through intact skin is limited, but contaminated dust on hands can be ingested.
Kidney effects (tubular injury/dysfunction) are the most consistent human finding from ingestion/inhalation of soluble uranium compounds.
Genotoxic/oxidative effects: Many cell/animal and some occupational studies report oxidative stress and chromosomal/DNA changes with sufficient exposure; relevance at low environmental levels is still being clarified.
Recent higher intake (e.g., switch to a private well, travel to high-uranium regions, new workplace tasks).
Hydration: Very dilute or very concentrated urine can complicate interpretation—hence creatinine correction. Repeat under similar conditions to compare.
Provoked testing (chelators/“challenge” tests) alters excretion and is not comparable to non-provoked reference ranges.
Reduce exposure at the source
If you use a private well, test it for uranium. Effective point-of-use options include reverse osmosis or anion-exchange; distillation also reduces uranium. Consider whole-house solutions if shower aerosols are a concern, but drinking/cooking water is the priority.
In workplaces with dust/fumes: improve local exhaust, follow housekeeping (wet-wiping/HEPA vacuum), and use appropriate PPE; avoid eating/drinking in work areas.
Support normal elimination
Adequate hydration facilitates urinary excretion. Do not start chelation on your own; for uranium, chelation is generally not recommended outside select, acute scenarios under specialist care due to limited benefit and potential kidney risks.
Follow-up testing
After exposure control, many clinicians retest in ~2–3 weeks under similar collection conditions (time of day, hydration) to confirm downward trend. Persistently high results warrant evaluation of water and workplace controls.
When to seek medical care
Symptoms of kidney stress (e.g., persistent flank pain, foamy urine, swelling), pregnancy/child results above range, or known significant inhalation/ingestion. A clinician (occupational/environmental medicine or nephrology) can assess kidney biomarkers and advise on remediation.
Typical U.S. urine uranium geometric means are in the single-digit ng/L range; the 95th percentile approximates 0.04 µg/g creatinine, similar to this panel’s upper reference.
Soluble uranium clears mainly via urine; most is excreted relatively quickly, but a few percent can remain in bone for months to years, explaining why elevations can persist until sources are fixed.
Regulatory context: The EPA drinking-water MCL is 30 µg/L, closely aligned with the WHO provisional guideline. If your home water exceeds this, address the water first.
Bottom line: A urine uranium level > 0.04 µg/g creatinine suggests recent exposure above reference. Prioritize water and workplace sources, ensure hydration, avoid self-chelation, and retest after mitigation to confirm improvement.
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A result above 0.04 µg/g creatinine on Vibrant’s Total Tox-Burden panel suggests recent uranium exposure higher than expected for the reference population. Because urine reflects what your body is eliminating, a high value points to exposure in the past days–weeks and cannot by itself date the exposure or quantify total body stores. The kidneys are the most sensitive organ to uranium’s chemical (heavy-metal) effects; some studies also link higher or prolonged exposure to oxidative stress and DNA/chromosomal changes.
Likely sources: drinking water from uranium-rich aquifers (especially private wells), foods or beverages prepared with such water, and inhalation of dust/fumes in mining, milling, ceramics, metallurgy, or similar workplaces. Dermal absorption is limited, but hand-to-mouth transfer of contaminated dust can matter.
What to do now
Reduce exposure at the source
Water: If you use a private well, test it for uranium. Short term, use bottled or alternative water for drinking and cooking. Long term, consider reverse osmosis or anion-exchange treatment (distillation is another option).
Workplace: Improve ventilation/local exhaust, use appropriate PPE (respiratory protection for dust/fumes, gloves), avoid eating/drinking in exposure areas, wet-wipe/HEPA vacuum, shower/change clothes after shifts, and launder work items separately.
Support normal elimination: Stay well hydrated. Avoid self-directed chelation or “detox” supplements; chelation for uranium is generally not recommended outside select acute situations under specialist care.
Check related health markers: Talk with your clinician about basic kidney testing (e.g., urinalysis, serum creatinine/eGFR) if your level is clearly elevated or you have symptoms.
Retest to confirm improvement: After exposure reduction, retest in ~2–3 weeks under similar conditions (same lab, unprovoked, similar time of day, usual hydration). Track trends rather than relying on a single value.
Seek medical care promptly if you have signs of kidney stress (e.g., flank pain, foamy urine, swelling), if you’re pregnant, if a child has an elevated result, or after a known significant inhalation/ingestion. Consider consultation with occupational/environmental medicine or nephrology.
Test tips: Results are creatinine-corrected, which helps account for urine dilution. Don’t compare non-provoked results to any provoked (chelator-assisted) test you may find online—reference ranges differ.
Bottom line: Focus first on water and workplace sources, maintain hydration, avoid unsupervised “detox” measures, and retest after changes to ensure your level is trending down.
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Anthony
Unlimited Plan Member since 2021
I have been using Healthmatters.io since 2021. I travel all over the world and use different doctors and health facilities. This site has allowed me to consolidate all my various test results over 14 years in one place. And every doctor that I show this to has been impressed. Because with any health professional I talk to, I can pull up historical results in seconds. It is invaluable. Even going back to the same doctor, they usually do not have the historical results from their facility in a graph format. That has been very helpful.
Karin
Advanced Plan Member since 2020
What fantastic service and great, easy-to-follow layouts! I love your website; it makes it so helpful to see patterns in my health data. It's truly a pleasure to use. I only wish the NHS was as organized and quick as Healthmatters.io. You've set a new standard for health tracking!
Paul
Healthmatters Pro Member since 2024
As a PRO member and medical practitioner, Healthmatters.io has been an invaluable tool for tracking my clients' data. The layout is intuitive, making it easy to monitor trends and spot patterns over time. The ability to customize reports and charts helps me present information clearly to my clients, improving communication and outcomes. It's streamlined my workflow, saving me time and providing insights at a glance. Highly recommended for any practitioner looking for a comprehensive and user-friendly solution to track patient labs!
Healthmatters is a highly-personalized health dashboard.
Instead of searching for your lab results in different places or tracking them down from different providers, Healthmatters houses, organizes, and interprets them all in one central location.
With a Healthmatters account, you can dive into the details of each biomarker and gain insights into the meaning behind your medical test data, anytime, anywhere.
For our professional users, Healthmatters provides intuitive tools that not only streamline analysis but also save valuable time when delving into your client's lab report history.
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If you are still determining whether Healthmatters support your lab results, the rule is that if you can test it, you can upload it to Healthmatters.
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We’ve crafted multiple ways for you to navigate your data, whether you're glancing at a single report or delving into your historical test reports.
1. Graph View:Dive into a visual journey with our biomarker graphs, showcasing over 40 data points. Combining years of results unveils trends, empowering you to make informed decisions. Our visualization tools make it a breeze to compare and understand changes over time, even if your results are from different labs. A search function and filters simplify the exploration of extensive data, allowing you to focus on what needs attention.
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Yes, you can. When entering values for the biomarker, you will see an "Edit Range" button. Click this button, and you'll have the option to enter a custom range.
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2,2-bis(4-Chlorophenyl) acetic acid (DDA), 2,4-Dichlorophenoxyacetic Acid (2,4-D), 2-3-4 Methylhippuric Acid (2,-3-,4-MHA), 2-Hydroxyethyl Mercapturic Acid (HEMA), 2-Hydroxyisobutyric Acid (2HIB), 2-Methylhippuric Acid (2MHA), 3-Methylhippuric Acid (3MHA), 3-Phenoxybenzoic Acid (3PBA), 4-Methylhippuric Acid (4MHA), 4-Nonylphenol, Aflatoxin B1 (AFB1), Aflatoxin B2 (AFB2), Aflatoxin G1, Aflatoxin G2, Aflatoxin M1, Aluminum, Antimony, Arsenic, Atrazine, Atrazine mercapturate, Barium, Beryllium, Bismuth, Bisphenol A (BPA), Bisphenol S (BPS), Butylparaben, Cadmium, Cesium, Chaetoglobosin A (CHA), Citrinin (CTN), Deoxynivalenol(DON), Diacetoxyscirpenol (DAS), Diethyl phosphate (DEP), Diethyldithiophosphate (DEDTP), Diethylphosphate (DEP), Diethylthiophosphate (DETP), Dihydrocitrinone, Dimethyl phosphate (DMP), Dimethyldithiophosphate (DMDTP), Dimethylthiophosphate (DMTP), Diphenyl Phosphate (DPP), Enniatin B1(ENN B1), Ethylparaben, Fumonisins B1, Fumonisins B2, Fumonisins B3, Gadolinium, GenX/HPFO-DA, Gliotoxin, Glyphosate, Lead, Mercury, Methylparaben, Mono-(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP), Mono-(2-ethyl-5-oxohexyl) phthalate, Mono-(2-ethyl-5-oxohexyl) phthalate (MEOHP), Mono-2-ethylhexyl phthalate (MEHP), Mono-2ethylhexyl phthalate (MEHP), Mono-ethyl phthalate (MEtP), Monobutyl phthalate (MBP), Monoethylphthalate (MEP), Monoisobutyl phthalate (MiBP), Mycophenolic Acid, N-Acetyl (2,Hydroxypropyl) Cysteine (NAHP), N-Acetyl (2-Cyanoethyl) Cysteine (NACE), N-Acetyl (3,4-Dihydroxybutyl) Cysteine, N-Acetyl (Carbomethyl) Cysteine (NAE), N-Acetyl (Propyl) Cysteine (NAPR), N-acetyl phenyl cysteine (NAP), N-acetyl-S-(2-carbamoylethyl)-cysteine, Nickel, Nivalenol (NIV), Ochratoxin A (OTA), Palladium, Patulin, Perchlorate (PERC), Perfluoroheptanoic acid (PFHpA), Perfluoropentanoic acid (PFPeA), Perfluoroundecanoic acid (PFUnA), Phenyl glyoxylic Acid (PGO), Platinum, Propylparaben, Roridin A, Roridin E, Roridin L2, Satratoxin G, Satratoxin H, Sterigmatocystin (STC), T-2 toxin, Tellurium, Thallium, Thorium, Tiglylglycine (TG), Tin, Triclosan (TCS), Tungsten, Uranium, Urine Creatinine, Verrucarin A, Verrucarin J, Zearalenone (ZEN)
