Optimal Result:
60 - 565 pg/MM WBC.
Common food sources:
Soybeans, beef, lamb, sunflower seeds, chicken, oats
Physiological Function:
→ Cysteine has antioxidant properties itself, but is also a precursor molecule to glutathione production, the master antioxidant.
→ Cysteine is also an important source of sulfide for iron-sulfide metabolism.
→ Cysteine will bind metals easily to its thiol group, such as iron, nickel, copper, zinc, and heavy metals such as mercury and lead, which may confer some chelation benefits.
→ Cysteine counteracts acetaldehyde effects from consumption of alcohol and can reduce hangovers.
Correlation between serum and WBC ("Cellular") levels:
WBC - normal and...
Serum levels deficient:
Long term nutrient status is optiomal, but short term needs improvement.
Possible interventions:
- increase dietary intake of nutrient
- increase supplementation dosage
- medications may have an effect on depletion
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What does it mean if your Cysteine (WBC) result is too low?
How it gets depleted:
Cysteine can be synthesized endogenously as long as sufficient methionine is available in the diet. Depletion is extremely rare.
Clinical Manifestations of Depletion:
Depletion or deficiency of cysteine is not common, as cysteine can be made endogenously, but can conditionally be required in greater amounts due to its strong antioxidant and detoxification properties.
Food Sources:
Dietary sources of cysteine include: meat, poultry, eggs, dairy, red peppers, garlic, onions, broccoli, Brussels sprouts, oats, granola, wheat germ, and lentils.
Supplement Options:
→ There is currently no established RDA, AI, or UL for cysteine.
→ Cysteine is typically purchased in supplement form as N-acetyl-cysteine (NAC).
→ Cysteine can be purchased as L-cysteine in powder form.
→ For general antioxidant support, doses start at 500mg/day and can increase depending upon direction from medical provider.
AVOID: D-cysteine or D-cystine, which are toxic.
Correlation between WBC ("Cellular") and serum levels:
WBC - deficient and...
Serum levels normal/excess:
Short term status of micronutrients is optiomal, but cellular absorption may be a problem.
Possible interventions:
- Increase dietary intake of nutrient
- increase supplementation dosage
- consider status of synergistic nutrients for cellular absorption
- consider levels of oxidative stress on nutrient depletion
- consider follow up testing to identify the source of malabsorption
Serum levels deficient:
Short term and long term status of micronutrients is not optimal, suggesting low dietary intake and both intestinal and cellular malabsorption as possible causes.
Possible interventions:
- Increase dietary intake of nutrient
- increase supplementation dosage
- medications may have an effect on depletion
- consider follow up testing to identify the source of malabsorption
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